Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) TacT2-ataR/DUF1778(antitoxin)
Location 3309125..3309900 Replicon chromosome
Accession NZ_CP022129
Organism Methylovulum psychrotolerans strain HV10_M2

Toxin (Protein)


Gene name TacT2 Uniprot ID -
Locus tag CEK71_RS15105 Protein ID WP_088620162.1
Coordinates 3309412..3309900 (+) Length 163 a.a.

Antitoxin (Protein)


Gene name ataR Uniprot ID -
Locus tag CEK71_RS15100 Protein ID WP_088620161.1
Coordinates 3309125..3309412 (+) Length 96 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CEK71_RS15085 3305042..3308095 + 3054 WP_088620158.1 efflux RND transporter permease subunit -
CEK71_RS15090 3308313..3308552 + 240 WP_088620159.1 hypothetical protein -
CEK71_RS15095 3308540..3308953 + 414 WP_088620160.1 type II toxin-antitoxin system VapC family toxin -
CEK71_RS15100 3309125..3309412 + 288 WP_088620161.1 DUF1778 domain-containing protein Antitoxin
CEK71_RS15105 3309412..3309900 + 489 WP_088620162.1 GNAT family N-acetyltransferase Toxin
CEK71_RS15110 3309963..3310469 + 507 WP_088620163.1 hypothetical protein -
CEK71_RS15115 3310490..3311440 + 951 WP_198328256.1 Fic family protein -
CEK71_RS15120 3311532..3311768 - 237 WP_088620164.1 DUF2281 domain-containing protein -
CEK71_RS15125 3311728..3312075 - 348 WP_157679288.1 hypothetical protein -
CEK71_RS15130 3312150..3312359 - 210 WP_157679290.1 hypothetical protein -
CEK71_RS15135 3312511..3314121 - 1611 WP_088620167.1 tetratricopeptide repeat protein -
CEK71_RS15140 3314428..3314733 + 306 WP_088621643.1 DUF3240 family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

GNAT domain

(41-142)

Antitoxin

Vibrio phage ICP1, Orf50

(16-79)


Sequences

Toxin        


Download         Length: 163 a.a.        Molecular weight: 17437.11 Da        Isoelectric Point: 8.4825

>T78524 WP_088620162.1 NZ_CP022129:3309412-3309900 [Methylovulum psychrotolerans]
MLSSPLLLAADHQLEHFACGTDSLDDWLKKRAYPNQLSGASRTYVVLDEARVVGYYCLASGALALNDAPSPVRRNMPNPI
PVAILGRLAIDQSYQGKGLGVALLQDATLRTAQASGILGIRGLLVHALSIQAKAFYEHHGFIASPTQEMTLILSLNGKIQ
SR

Download         Length: 489 bp

>T78524 NZ_CP022129:3309412-3309900 [Methylovulum psychrotolerans]
ATGCTGTCTTCGCCCTTGCTGCTGGCGGCGGATCATCAGCTTGAACATTTTGCTTGTGGTACCGACAGCCTTGATGATTG
GCTAAAGAAACGGGCATACCCCAATCAGCTCAGCGGAGCCTCCCGCACTTATGTGGTTTTAGACGAAGCAAGGGTTGTCG
GCTACTATTGCCTAGCGTCAGGCGCACTGGCATTAAACGATGCGCCTAGCCCTGTGCGCCGCAATATGCCCAACCCTATC
CCCGTCGCCATTCTTGGCCGTCTTGCCATTGACCAATCTTATCAGGGCAAAGGGCTAGGGGTTGCTTTGCTGCAAGATGC
CACCTTGCGCACCGCCCAAGCCAGCGGCATTCTTGGCATACGCGGCCTGCTGGTCCACGCGCTGTCCATTCAGGCTAAAG
CTTTTTATGAGCATCATGGTTTTATCGCCTCACCGACCCAGGAGATGACCTTAATACTTTCTTTGAATGGAAAAATACAA
AGCCGATAA

Antitoxin


Download         Length: 96 a.a.        Molecular weight: 10708.11 Da        Isoelectric Point: 6.7252

>AT78524 WP_088620161.1 NZ_CP022129:3309125-3309412 [Methylovulum psychrotolerans]
MPDKHTLTDNQTHAVNLRVRHDIRSLIDRAAKAQGKTRSDFMIDAARRAAEESLLDQALVQVDPATYAQFLEVLDLPPNG
EGFARLMNAPRPWDK

Download         Length: 288 bp

>AT78524 NZ_CP022129:3309125-3309412 [Methylovulum psychrotolerans]
ATGCCTGACAAACACACCCTAACCGACAACCAAACCCATGCCGTTAACCTGCGTGTCCGCCATGACATCCGCAGCCTGAT
TGATAGGGCGGCAAAGGCGCAAGGTAAAACCCGTTCGGATTTTATGATTGATGCCGCCCGCCGCGCAGCGGAAGAGTCCC
TGCTTGACCAAGCGCTCGTGCAAGTTGACCCGGCCACTTACGCGCAGTTTCTTGAAGTGCTGGACTTACCGCCTAACGGC
GAGGGCTTTGCAAGGCTTATGAACGCGCCTAGGCCTTGGGATAAATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References