Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-YafN
Location 192188..192723 Replicon plasmid unnamed1
Accession NZ_CP022118
Organism Salmonella enterica subsp. enterica serovar Macclesfield str. S-1643

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag LFZ25_RS25495 Protein ID WP_088731528.1
Coordinates 192436..192723 (+) Length 96 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag LFZ25_RS25490 Protein ID WP_088731526.1
Coordinates 192188..192439 (+) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LFZ25_RS25480 189689..190177 - 489 WP_088731522.1 LuxR C-terminal-related transcriptional regulator -
LFZ25_RS25485 190259..191104 - 846 WP_088731524.1 AraC family transcriptional regulator -
LFZ25_RS25490 192188..192439 + 252 WP_088731526.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
LFZ25_RS25495 192436..192723 + 288 WP_088731528.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
LFZ25_RS27315 192992..193255 + 264 WP_198387427.1 hypothetical protein -
LFZ25_RS25500 193230..194209 + 980 Protein_171 IS256 family transposase -
LFZ25_RS25505 194476..194688 - 213 WP_088731779.1 hypothetical protein -
LFZ25_RS27145 194791..194964 - 174 WP_157719624.1 hypothetical protein -
LFZ25_RS25510 194983..195810 - 828 WP_088731782.1 outer membrane protein assembly factor BamE -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..416444 416444


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(3-120)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 96 a.a.        Molecular weight: 12322.73 Da        Isoelectric Point: 12.7777

>T78480 WP_088731528.1 NZ_CP022118:192436-192723 [Salmonella enterica subsp. enterica serovar Macclesfield str.]
KKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKK
KKKKKKKKKKKKKKKK

Download         Length: 288 bp

>T78480 NZ_CP022118:192436-192723 [Salmonella enterica subsp. enterica serovar Macclesfield str.]
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 10784.64 Da        Isoelectric Point: 12.7191

>AT78480 WP_088731526.1 NZ_CP022118:192188-192439 [Salmonella enterica subsp. enterica serovar Macclesfield str.]
KKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKK
KKKK

Download         Length: 252 bp

>AT78480 NZ_CP022118:192188-192439 [Salmonella enterica subsp. enterica serovar Macclesfield str.]
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References