Detailed information of TA system TA078477

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/RelE-RelB
• Location: 40575..41173
• Replicon: chromosome
• Accession: NZ_CP022112
• Organism: Nitrospirillum amazonense CBAmc

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: Y958_RS22185
• Protein ID: WP_211098750.1
• Coordinates: 40976..41173 (+)
• Length: 66 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: -
• Locus tag: Y958_RS22180
• Protein ID: WP_088874178.1
• Coordinates: 40575..40889 (+)
• Length: 105 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
Y958_RS22165	36462..38732	-	2271	WP_186291610.1	glycoside hydrolase family 3 C-terminal domain-containing protein	-
Y958_RS22170	39043..39414	+	372	WP_088874176.1	hypothetical protein	-
Y958_RS22175	39419..40411	-	993	WP_088874177.1	transcriptional regulator FtrA	-
Y958_RS22180	40575..40889	+	315	WP_088874178.1	type II toxin-antitoxin system RelB/DinJ family antitoxin	Antitoxin
Y958_RS22185	40976..41173	+	198	WP_211098750.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
Y958_RS22190	41214..41561	-	348	WP_088874179.1	VOC family protein	-
Y958_RS22195	41656..42159	-	504	WP_088875158.1	RES domain-containing protein	-
Y958_RS22200	42171..42539	-	369	WP_088874180.1	DUF2384 domain-containing protein	-
Y958_RS22205	42727..43149	+	423	WP_088874181.1	rhodanese	-
Y958_RS22210	43155..43598	-	444	WP_211098780.1	GNAT family N-acetyltransferase	-
Y958_RS22215	43704..45767	-	2064	WP_186291557.1	HAMP domain-containing protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (2-60)

Antitoxin

• RelB antitoxin/Antitoxin DinJ (1-51)

Sequences

Toxin

Protein

• Length: 66 a.a.
• Molecular weight: 7306.55 Da
• Isoelectric Point: 7.3172

>T78477 WP_211098750.1 NZ_CP022112:40976-41173 [Nitrospirillum amazonense CBAmc]
MDDRIHAAVQGLKAFPEKGRPGRVPPTRELVIPDTPYIAAYHVEKGVILILRVLHTAQLWPEDLP

Nucleotide

• Length: 198 bp

>T78477 NZ_CP022112:40976-41173 [Nitrospirillum amazonense CBAmc]
ATGGATGATCGTATCCATGCCGCCGTTCAAGGCTTGAAGGCCTTTCCCGAAAAAGGTCGGCCCGGGCGTGTGCCGCCGAC
GCGAGAGCTGGTGATCCCCGATACACCGTACATCGCCGCGTATCATGTGGAAAAGGGCGTTATCCTTATTCTACGTGTCC
TGCACACGGCGCAGCTTTGGCCGGAGGATTTGCCCTAA

Antitoxin

Protein

• Length: 105 a.a.
• Molecular weight: 11287.66 Da
• Isoelectric Point: 4.7051

>AT78477 WP_088874178.1 NZ_CP022112:40575-40889 [Nitrospirillum amazonense CBAmc]
MVSNALVQTRIDADVKERAAAVLESMGLTVSDAVRILLTRTANEGALPFLLADGPAHDAWFRAKVRQALEDARPSLEEDE
VEARFAQRRDALRRVAGNADGGDT

Nucleotide

• Length: 315 bp

>AT78477 NZ_CP022112:40575-40889 [Nitrospirillum amazonense CBAmc]
ATGGTCAGCAATGCCTTGGTGCAGACGCGCATTGACGCCGATGTGAAGGAGCGGGCTGCCGCCGTGCTGGAAAGCATGGG
GCTGACAGTATCGGATGCCGTCCGTATCCTGCTGACCCGGACCGCCAATGAGGGGGCGCTGCCCTTCCTGCTAGCGGATG
GTCCGGCCCACGATGCCTGGTTTCGCGCCAAGGTGCGCCAAGCGCTGGAAGATGCCCGCCCCAGCCTGGAGGAAGACGAG
GTGGAGGCCCGTTTCGCGCAGCGGCGCGACGCCCTGCGCCGGGTCGCGGGCAACGCGGACGGGGGTGACACGTGA