78476

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) tad-ata/Tad-HTH_37
Location 1755912..1756593 Replicon chromosome
Accession NZ_CP022111
Organism Nitrospirillum amazonense CBAmc

Toxin (Protein)


Gene name tad Uniprot ID -
Locus tag Y958_RS21015 Protein ID WP_088873817.1
Coordinates 1756216..1756593 (-) Length 126 a.a.

Antitoxin (Protein)


Gene name ata Uniprot ID -
Locus tag Y958_RS21010 Protein ID WP_088873816.1
Coordinates 1755912..1756223 (-) Length 104 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
Y958_RS20980 1751737..1751964 - 228 WP_145727655.1 hypothetical protein -
Y958_RS20985 1751994..1753337 + 1344 WP_088873812.1 MFS transporter -
Y958_RS20990 1753307..1753876 - 570 WP_088873813.1 hypothetical protein -
Y958_RS21000 1754307..1754828 - 522 WP_186291384.1 META domain-containing protein -
Y958_RS21005 1755041..1755901 - 861 WP_088873815.1 class I SAM-dependent methyltransferase -
Y958_RS21010 1755912..1756223 - 312 WP_088873816.1 helix-turn-helix domain-containing protein Antitoxin
Y958_RS21015 1756216..1756593 - 378 WP_088873817.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
Y958_RS21020 1756849..1757997 - 1149 WP_088873818.1 tRNA 2-thiouridine(34) synthase MnmA -
Y958_RS21025 1758202..1758516 - 315 WP_040848268.1 ferredoxin family 2Fe-2S iron-sulfur cluster binding protein -
Y958_RS21030 1758763..1759452 + 690 WP_145727654.1 hypothetical protein -
Y958_RS21035 1759601..1761574 + 1974 WP_088874133.1 CocE/NonD family hydrolase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-like

(16-109)

Antitoxin

Cro/C1-type helix-turn-helix domain

(31-87)


Sequences

Toxin        


Download         Length: 126 a.a.        Molecular weight: 14489.54 Da        Isoelectric Point: 9.9467

>T78476 WP_088873817.1 NZ_CP022111:c1756593-1756216 [Nitrospirillum amazonense CBAmc]
MVLGRREVRWVASSHKDLREFPEDVQDLVGFGLYQAQIGKKHPNAKPLKGFGGSQILELLDDHDGDAYRCVYTVRFEAAI
YVLHAFQKKSKRGIATPQADMDLIRTRLKLAEEDHRRRQKDKRNE

Download         Length: 378 bp

>T78476 NZ_CP022111:c1756593-1756216 [Nitrospirillum amazonense CBAmc]
ATGGTTTTGGGAAGACGAGAAGTCCGATGGGTAGCCTCAAGCCATAAGGATTTGAGGGAATTTCCTGAGGATGTTCAAGA
TTTGGTGGGCTTCGGACTTTACCAAGCCCAAATTGGGAAAAAGCATCCCAATGCGAAGCCGCTGAAGGGCTTTGGCGGCA
GTCAGATTTTAGAATTGCTTGATGACCATGATGGGGATGCGTACCGGTGCGTCTATACGGTCCGCTTTGAAGCCGCCATC
TATGTCCTTCATGCCTTTCAGAAGAAATCGAAGAGGGGTATCGCTACCCCTCAAGCCGATATGGATTTAATTCGGACCCG
CCTGAAGTTGGCTGAAGAAGATCATCGTCGGCGCCAAAAGGATAAGCGCAATGAGTAA

Antitoxin


Download         Length: 104 a.a.        Molecular weight: 11138.84 Da        Isoelectric Point: 5.8355

>AT78476 WP_088873816.1 NZ_CP022111:c1756223-1755912 [Nitrospirillum amazonense CBAmc]
MSNDVMVSSGNIFADLGLPDPEIRQVKAEIASRISDVIEERKLTQAQAAQILGIDQPKVSALVRGKLSGFTLDRLLRFLN
DLDVDVEIRLTPAKGKAHTAVAA

Download         Length: 312 bp

>AT78476 NZ_CP022111:c1756223-1755912 [Nitrospirillum amazonense CBAmc]
ATGAGTAACGACGTAATGGTGAGTAGCGGCAACATCTTCGCGGACTTAGGCTTGCCTGACCCGGAAATACGCCAGGTCAA
GGCGGAAATTGCGTCGCGCATCAGTGACGTGATCGAAGAACGTAAGCTGACCCAGGCCCAGGCGGCGCAAATCCTGGGCA
TTGATCAGCCCAAGGTGTCCGCCCTGGTCCGGGGCAAGCTGTCGGGTTTTACCCTGGATCGGTTGCTGCGTTTCCTGAAT
GATCTGGACGTGGACGTGGAAATTCGCCTGACGCCGGCCAAGGGTAAGGCGCACACCGCCGTCGCTGCTTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References