Detailed information of TA system TA078475

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): vapBC/VapC-VagC
• Location: 1458674..1459314
• Replicon: chromosome
• Accession: NZ_CP022111
• Organism: Nitrospirillum amazonense CBAmc

Toxin (Protein)

• Gene name: vapC
• Uniprot ID: -
• Locus tag: Y958_RS19675
• Protein ID: WP_088873613.1
• Coordinates: 1458925..1459314 (+)
• Length: 130 a.a.

Antitoxin (Protein)

• Gene name: vapB
• Uniprot ID: -
• Locus tag: Y958_RS19670
• Protein ID: WP_211098628.1
• Coordinates: 1458674..1458928 (+)
• Length: 85 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
Y958_RS19655	1456832..1457074	-	243	WP_088873611.1	type II toxin-antitoxin system RelE/ParE family toxin	-
Y958_RS19660	1457067..1457321	-	255	WP_211098627.1	type II toxin-antitoxin system ParD family antitoxin	-
Y958_RS19665	1457491..1458624	+	1134	WP_088873612.1	serine hydrolase	-
Y958_RS19670	1458674..1458928	+	255	WP_211098628.1	AbrB/MazE/SpoVT family DNA-binding domain-containing protein	Antitoxin
Y958_RS19675	1458925..1459314	+	390	WP_088873613.1	type II toxin-antitoxin system VapC family toxin	Toxin
Y958_RS19680	1459392..1461212	-	1821	WP_088873614.1	aspartate--tRNA ligase	-
Y958_RS19685	1461365..1463512	-	2148	WP_088873615.1	TonB-dependent siderophore receptor	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• PIN domain (4-121)

Antitoxin

• SpoVT-AbrB domain (11-48)

Sequences

Toxin

Protein

• Length: 130 a.a.
• Molecular weight: 14325.44 Da
• Isoelectric Point: 6.8814

>T78475 WP_088873613.1 NZ_CP022111:1458925-1459314 [Nitrospirillum amazonense CBAmc]
VKFLLDTNAVIAVMKGDPVFLDRMRQHRPEDFGLPTIVAHELYFGAAKSQRAAENLARVEALRFPVLDLDREDARQAGLI
RAQLAATGTPVGPYDVLIAGQALARGLTLVTHNTREFQRVPGLHLEDWQ

Nucleotide

• Length: 390 bp

>T78475 NZ_CP022111:1458925-1459314 [Nitrospirillum amazonense CBAmc]
GTGAAGTTTCTTCTGGATACCAACGCCGTCATCGCGGTGATGAAGGGCGATCCCGTCTTTCTGGATCGGATGCGGCAGCA
CAGGCCGGAGGATTTCGGCCTGCCCACCATCGTCGCGCATGAACTCTACTTCGGCGCGGCCAAGAGCCAGCGCGCGGCGG
AAAACCTGGCGCGTGTCGAGGCCCTGCGCTTCCCTGTCCTGGACCTCGACCGGGAGGACGCCCGGCAGGCCGGCCTTATC
CGGGCGCAGCTGGCCGCCACCGGCACGCCCGTCGGTCCCTATGATGTGCTGATCGCGGGTCAGGCGCTGGCCCGTGGCCT
GACCCTGGTCACGCACAACACCCGGGAATTCCAGCGCGTGCCGGGGCTGCACCTGGAAGACTGGCAGTAG

Antitoxin

Protein

• Length: 85 a.a.
• Molecular weight: 9665.86 Da
• Isoelectric Point: 4.3217

>AT78475 WP_211098628.1 NZ_CP022111:1458674-1458928 [Nitrospirillum amazonense CBAmc]
MEMAMDTAKLFWSGRSQAVRLPKDFRFEGEEVRIRRHGNAVILEPIADGWEWLADVIGPVDEDFAKAATDRPTDQERPAL
DFFE

Nucleotide

• Length: 255 bp

>AT78475 NZ_CP022111:1458674-1458928 [Nitrospirillum amazonense CBAmc]
ATGGAGATGGCCATGGATACCGCCAAGCTCTTCTGGTCCGGCCGCTCGCAGGCCGTGCGCCTGCCCAAGGACTTCCGGTT
CGAGGGTGAGGAGGTGCGCATCCGCCGTCATGGCAACGCCGTGATCCTGGAACCCATCGCCGACGGCTGGGAGTGGCTGG
CGGATGTCATCGGACCGGTGGATGAGGACTTCGCCAAGGCCGCCACAGACCGGCCGACCGATCAAGAGCGCCCGGCCCTG
GACTTCTTCGAGTGA