Detailed information of TA system TA078474

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): parDE/RHH(antitoxin)
• Location: 1456832..1457321
• Replicon: chromosome
• Accession: NZ_CP022111
• Organism: Nitrospirillum amazonense CBAmc

Toxin (Protein)

• Gene name: parE
• Uniprot ID: -
• Locus tag: Y958_RS19655
• Protein ID: WP_088873611.1
• Coordinates: 1456832..1457074 (-)
• Length: 81 a.a.

Antitoxin (Protein)

• Gene name: parD
• Uniprot ID: -
• Locus tag: Y958_RS19660
• Protein ID: WP_211098627.1
• Coordinates: 1457067..1457321 (-)
• Length: 85 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
Y958_RS19650	1453248..1456439	-	3192	WP_088874104.1	metallophosphoesterase	-
Y958_RS19655	1456832..1457074	-	243	WP_088873611.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
Y958_RS19660	1457067..1457321	-	255	WP_211098627.1	type II toxin-antitoxin system ParD family antitoxin	Antitoxin
Y958_RS19665	1457491..1458624	+	1134	WP_088873612.1	serine hydrolase	-
Y958_RS19670	1458674..1458928	+	255	WP_211098628.1	AbrB/MazE/SpoVT family DNA-binding domain-containing protein	-
Y958_RS19675	1458925..1459314	+	390	WP_088873613.1	type II toxin-antitoxin system VapC family toxin	-
Y958_RS19680	1459392..1461212	-	1821	WP_088873614.1	aspartate--tRNA ligase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Genomic island	-	-	1446815..1457321	10506

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (5-75)

Antitoxin

• Antitoxin ParD (1-71)

Sequences

Toxin

Protein

• Length: 81 a.a.
• Molecular weight: 9074.33 Da
• Isoelectric Point: 9.9759

>T78474 WP_088873611.1 NZ_CP022111:c1457074-1456832 [Nitrospirillum amazonense CBAmc]
MGEYALSGKARNDLKRIAQQSLTQWGMAQAERYVVGLHELFGRLVTFPDLGRDAGEIRPGYLRIESGSHVVFYRQSSTRM

Nucleotide

• Length: 243 bp

>T78474 NZ_CP022111:c1457074-1456832 [Nitrospirillum amazonense CBAmc]
ATGGGTGAGTACGCGCTTTCCGGCAAGGCGCGGAACGATCTGAAGCGCATCGCTCAGCAGTCGTTGACGCAGTGGGGCAT
GGCGCAGGCGGAGCGCTATGTAGTCGGGCTGCACGAATTGTTCGGGCGGCTGGTCACGTTCCCCGATTTGGGGCGTGATG
CCGGGGAGATACGTCCGGGCTATCTGCGGATTGAGAGCGGAAGCCACGTTGTCTTCTATCGCCAGTCTTCCACGCGCATG
TGA

Antitoxin

Protein

• Length: 85 a.a.
• Molecular weight: 8865.82 Da
• Isoelectric Point: 4.4423

>AT78474 WP_211098627.1 NZ_CP022111:c1457321-1457067 [Nitrospirillum amazonense CBAmc]
MGKNTSVSLGEHFTQFVETQVAQGRYGSASEVMRAGLRLLEEREAKLAALRAALDEGEASGISSQNVLDIWAEVKAEAGE
AGNG

Nucleotide

• Length: 255 bp

>AT78474 NZ_CP022111:c1457321-1457067 [Nitrospirillum amazonense CBAmc]
ATGGGCAAGAACACGTCGGTCAGCTTGGGTGAGCATTTCACCCAATTCGTGGAAACACAGGTCGCCCAAGGCCGTTACGG
CAGCGCCAGCGAGGTCATGCGGGCAGGCCTTCGTCTGCTGGAAGAGCGTGAGGCCAAACTCGCCGCCCTCCGCGCGGCCC
TGGACGAGGGGGAGGCCAGCGGCATCAGCAGCCAGAACGTCCTGGATATCTGGGCTGAGGTGAAGGCTGAGGCGGGCGAA
GCCGGGAATGGGTGA