Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) tacT-ataR/DUF1778(antitoxin)
Location 2774685..2775465 Replicon chromosome
Accession NZ_CP022110
Organism Nitrospirillum amazonense CBAmc

Toxin (Protein)


Gene name tacT Uniprot ID -
Locus tag Y958_RS12805 Protein ID WP_186291186.1
Coordinates 2774685..2775170 (-) Length 162 a.a.

Antitoxin (Protein)


Gene name ataR Uniprot ID -
Locus tag Y958_RS12810 Protein ID WP_211098497.1
Coordinates 2775184..2775465 (-) Length 94 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
Y958_RS12775 2769755..2770453 - 699 WP_088872270.1 cytochrome c-type biogenesis protein CcmH -
Y958_RS12780 2770450..2770995 - 546 WP_088872271.1 DsbE family thiol:disulfide interchange protein -
Y958_RS12785 2771006..2773006 - 2001 WP_088872272.1 heme lyase CcmF/NrfE family subunit -
Y958_RS12790 2773031..2773522 - 492 WP_088872273.1 cytochrome c maturation protein CcmE -
Y958_RS12795 2773519..2773740 - 222 WP_088872274.1 heme exporter protein CcmD -
Y958_RS12800 2773868..2774584 - 717 WP_088872275.1 heme ABC transporter permease -
Y958_RS12805 2774685..2775170 - 486 WP_186291186.1 GNAT family N-acetyltransferase Toxin
Y958_RS12810 2775184..2775465 - 282 WP_211098497.1 DUF1778 domain-containing protein Antitoxin
Y958_RS12815 2775535..2776191 - 657 WP_088872276.1 heme exporter protein CcmB -
Y958_RS12820 2776191..2776850 - 660 WP_088872277.1 heme ABC exporter ATP-binding protein CcmA -
Y958_RS12825 2777794..2778924 + 1131 WP_088872278.1 type III PLP-dependent enzyme -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

GNAT domain

(42-143)

Antitoxin

Vibrio phage ICP1, Orf50

(14-85)


Sequences

Toxin        


Download         Length: 162 a.a.        Molecular weight: 17355.77 Da        Isoelectric Point: 9.8544

>T78470 WP_186291186.1 NZ_CP022110:c2775170-2774685 [Nitrospirillum amazonense CBAmc]
VTLTAPTPLGETHDLDQFQSGHDTLDHWLRRRARANQVNGASRTYVVAEGRRVVGYYCLASGALDISDAPGAIRRNMPDP
IPMAVLGRLAIDRTWQGRGLGTALLQDAVLRSSQAASILGIRGLLVHAISDAAKAFYERYGFVGTPNHPLTLVLSLKAQG
N

Download         Length: 486 bp

>T78470 NZ_CP022110:c2775170-2774685 [Nitrospirillum amazonense CBAmc]
GTGACGCTGACAGCGCCAACACCGCTGGGCGAAACGCACGACCTCGACCAATTCCAAAGCGGCCATGACACGCTGGACCA
TTGGCTGCGGCGGCGCGCCCGCGCCAATCAGGTCAATGGCGCTTCCCGCACCTATGTCGTGGCCGAAGGCCGGCGGGTGG
TCGGCTATTACTGCCTCGCGTCCGGGGCGCTGGACATATCTGACGCGCCTGGCGCTATCCGGCGCAACATGCCCGATCCT
ATTCCCATGGCCGTACTCGGCCGGCTGGCCATCGATCGGACCTGGCAGGGCAGAGGCCTGGGTACCGCGTTGTTGCAGGA
CGCAGTGCTGCGCAGCTCGCAGGCCGCATCGATCCTGGGGATACGCGGTCTGCTCGTCCACGCGATCTCGGATGCGGCTA
AGGCGTTTTATGAGCGCTACGGCTTCGTGGGCACGCCCAACCATCCGCTGACGCTCGTGCTGTCGCTCAAGGCCCAAGGT
AACTAA

Antitoxin


Download         Length: 94 a.a.        Molecular weight: 10533.10 Da        Isoelectric Point: 9.5887

>AT78470 WP_211098497.1 NZ_CP022110:c2775465-2775184 [Nitrospirillum amazonense CBAmc]
MTKPSVGTHAKPVNLRIREDVRRVIDRAAGLRGKTRSDFMIEAAYRAAEDTLLDQALVRVDVDSYRHYLALLDQPPGGEG
FERLMKAPKPWEV

Download         Length: 282 bp

>AT78470 NZ_CP022110:c2775465-2775184 [Nitrospirillum amazonense CBAmc]
ATGACCAAGCCATCCGTGGGAACCCATGCGAAGCCCGTGAACCTGCGCATCCGCGAGGATGTTCGGCGGGTGATAGATCG
TGCGGCCGGCTTGCGCGGCAAAACCCGGTCGGACTTCATGATCGAGGCGGCCTATCGCGCCGCTGAAGACACGCTGCTGG
ACCAGGCGCTGGTGCGGGTCGATGTCGATAGCTATCGGCACTATCTCGCCCTTCTAGACCAGCCACCCGGCGGTGAAGGG
TTTGAGCGCCTGATGAAGGCACCCAAGCCTTGGGAAGTATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References