Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) rlegTA/AbiEii-AbiEi
Location 1071190..1072651 Replicon chromosome
Accession NZ_CP022110
Organism Nitrospirillum amazonense CBAmc

Toxin (Protein)


Gene name rlegT Uniprot ID -
Locus tag Y958_RS04965 Protein ID WP_088871130.1
Coordinates 1071740..1072651 (+) Length 304 a.a.

Antitoxin (Protein)


Gene name rlegA Uniprot ID -
Locus tag Y958_RS04960 Protein ID WP_211098532.1
Coordinates 1071190..1071750 (+) Length 187 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
Y958_RS04950 1066811..1067662 + 852 WP_088871127.1 hypothetical protein -
Y958_RS31220 1067681..1069363 + 1683 WP_211098531.1 N-6 DNA methylase -
Y958_RS31225 1069360..1069986 + 627 WP_145727996.1 hypothetical protein -
Y958_RS04955 1070093..1071028 + 936 WP_186291265.1 DUF4365 domain-containing protein -
Y958_RS04960 1071190..1071750 + 561 WP_211098532.1 type IV toxin-antitoxin system AbiEi family antitoxin domain-containing protein Antitoxin
Y958_RS04965 1071740..1072651 + 912 WP_088871130.1 nucleotidyl transferase AbiEii/AbiGii toxin family protein Toxin
Y958_RS04970 1073091..1074686 - 1596 WP_088872484.1 IS66 family transposase -
Y958_RS04975 1074794..1075141 - 348 WP_088871131.1 IS66 family insertion sequence element accessory protein TnpB -
Y958_RS04980 1075138..1075551 - 414 WP_186291266.1 transposase -
Y958_RS04985 1075857..1076498 - 642 WP_088872485.1 DsbA family protein -
Y958_RS04990 1076583..1077509 - 927 WP_088871133.1 SDR family NAD(P)-dependent oxidoreductase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 1009343..1082134 72791


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Nucleotidyl transferase AbiEii toxin, Type IV TA system

(39-258)

Antitoxin

Transcriptional regulator, AbiEi antitoxin

(2-35)


Sequences

Toxin        


Download         Length: 304 a.a.        Molecular weight: 33933.69 Da        Isoelectric Point: 4.8173

>T78464 WP_088871130.1 NZ_CP022110:1071740-1072651 [Nitrospirillum amazonense CBAmc]
MAREPRKNVGASVRARLLDRSRVERTDFQILLTRYALERLLYRLSQSPHRDRFVLKGAMLFVTWVEDPFRPTRDLDFLGY
GENSPESIGGAFREICGQPVDDDGVEFDIVAITAVPIREDVEYGGIRVRTSATIAGARVPIQVDIGFGDAVTPGPVEIVY
PPLLDAPAPRLRAYPVTTVVAEKFQALVQLGIANSRLKDFYDLWLIAQTFEFDRASLEEAVRQTFARRETMLPTENPIGL
SDAYVEAWGRQWQAFLGRERMAAAPADLAVVVSDLAGFLLPLIEPAEKDERWKPGEGWRASNA

Download         Length: 912 bp

>T78464 NZ_CP022110:1071740-1072651 [Nitrospirillum amazonense CBAmc]
ATGGCGCGTGAGCCCAGGAAAAATGTCGGTGCTTCGGTCCGGGCTCGTCTGCTCGACCGGTCTCGCGTCGAACGCACGGA
CTTCCAGATTTTGCTGACGCGCTACGCGCTGGAACGGCTTCTCTACCGGCTGAGCCAGTCACCCCACCGCGACCGCTTTG
TTCTGAAGGGAGCGATGCTGTTCGTGACCTGGGTAGAAGACCCGTTCCGGCCGACACGCGATCTCGATTTCCTCGGCTAT
GGCGAAAACAGCCCTGAGTCGATCGGCGGGGCCTTTCGCGAGATCTGCGGGCAACCGGTCGATGATGATGGCGTGGAGTT
CGATATCGTCGCGATCACGGCTGTTCCGATCCGAGAGGACGTTGAATACGGCGGCATTCGCGTACGCACCTCCGCGACGA
TCGCCGGTGCCCGCGTTCCGATTCAGGTCGACATCGGTTTTGGTGACGCTGTAACTCCGGGACCCGTCGAAATCGTCTAT
CCGCCGCTGCTCGACGCGCCGGCGCCCCGCCTGCGCGCTTATCCGGTGACGACAGTGGTTGCCGAAAAATTCCAGGCGCT
CGTCCAGCTCGGCATCGCGAACAGCCGGCTGAAGGATTTCTACGACCTCTGGCTGATCGCGCAGACATTCGAGTTTGACC
GCGCATCCCTTGAAGAGGCCGTCCGTCAGACCTTTGCACGGCGCGAGACCATGCTTCCAACCGAAAATCCGATCGGTCTG
AGCGATGCTTACGTGGAGGCTTGGGGGCGCCAGTGGCAGGCCTTTCTGGGACGAGAGCGAATGGCCGCGGCGCCGGCCGA
CCTGGCTGTCGTCGTCTCCGACCTCGCCGGATTTCTGCTTCCCCTGATCGAGCCTGCTGAAAAGGATGAGCGTTGGAAGC
CTGGCGAAGGCTGGAGGGCATCGAATGCATAG

Antitoxin


Download         Length: 187 a.a.        Molecular weight: 20585.90 Da        Isoelectric Point: 9.7214

>AT78464 WP_211098532.1 NZ_CP022110:1071190-1071750 [Nitrospirillum amazonense CBAmc]
MRLKDFAARGIAPETLARLVRDGEVVRPARGIYQLADSSGDAARVLAEASLLVPKGIICLTSALQFHELTLQMPSAVWMA
IDRTAWRPKIDYPPIRFVRFTGASLTEGVERHAIDGIEVAITNPARTIVDCFRYRAKVGLDVALEGLREGLRQRKVTSDQ
LWTYGTKGKVWTTMKPYVEAMVADGA

Download         Length: 561 bp

>AT78464 NZ_CP022110:1071190-1071750 [Nitrospirillum amazonense CBAmc]
ATGCGGCTGAAGGACTTTGCCGCCCGCGGCATCGCGCCCGAAACCCTGGCGCGTCTTGTCCGGGACGGCGAGGTTGTTCG
TCCCGCGCGCGGGATCTACCAGCTCGCAGATAGCTCGGGCGATGCGGCGCGCGTCCTGGCCGAAGCATCGCTGCTCGTTC
CCAAAGGCATCATCTGTCTGACCTCGGCGCTGCAGTTCCACGAGCTGACGCTGCAAATGCCGTCGGCCGTTTGGATGGCC
ATCGATCGTACCGCCTGGCGTCCCAAGATCGACTATCCACCCATTCGCTTCGTGCGCTTCACCGGCGCCTCGCTGACAGA
AGGTGTCGAGCGGCACGCCATCGATGGCATCGAGGTGGCGATCACAAATCCGGCGCGCACGATCGTCGATTGCTTCCGCT
ATCGGGCAAAGGTCGGTCTGGATGTCGCTCTGGAAGGTCTGCGTGAGGGGCTTCGACAACGGAAAGTCACAAGCGACCAG
CTCTGGACTTATGGGACCAAAGGCAAGGTTTGGACGACCATGAAACCCTATGTGGAGGCAATGGTAGCCGATGGCGCGTG
A

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References