Detailed information of TA system TA078462

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/RHH(antitoxin)
• Location: 657040..657575
• Replicon: chromosome
• Accession: NZ_CP022110
• Organism: Nitrospirillum amazonense CBAmc

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: Y958_RS03070
• Protein ID: WP_186291239.1
• Coordinates: 657324..657575 (+)
• Length: 84 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: -
• Locus tag: Y958_RS03065
• Protein ID: WP_088870863.1
• Coordinates: 657040..657288 (+)
• Length: 83 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
Y958_RS03045	652300..653889	-	1590	WP_088870862.1	2,3-bisphosphoglycerate-independent phosphoglycerate mutase	-
Y958_RS03050	654197..655435	+	1239	WP_088872442.1	ornithine--oxo-acid transaminase	-
Y958_RS03055	655489..656388	+	900	WP_211098517.1	amidinotransferase	-
Y958_RS03060	656473..656958	+	486	WP_088872444.1	Lrp/AsnC family transcriptional regulator	-
Y958_RS03065	657040..657288	+	249	WP_088870863.1	ribbon-helix-helix protein, CopG family	Antitoxin
Y958_RS03070	657324..657575	+	252	WP_186291239.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
Y958_RS03075	657716..658747	+	1032	WP_088870865.1	aldo/keto reductase	-
Y958_RS03080	658823..660091	-	1269	WP_088870866.1	MgtC/SapB family protein	-
Y958_RS03085	660184..662127	-	1944	WP_088870867.1	DUF47 family protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (2-77)

Antitoxin

• Ribbon-helix-helix protein, CopG (6-42)

Sequences

Toxin

Protein

• Length: 84 a.a.
• Molecular weight: 9209.51 Da
• Isoelectric Point: 9.8544

>T78462 WP_186291239.1 NZ_CP022110:657324-657575 [Nitrospirillum amazonense CBAmc]
VDIHDYLNQFNSAAALKLVKSLRAQAQGLGSHPQKGRPGRINGTRELVISGTDFIIAYQIAETCVDILAVRHTAREWPAR
LDR

Nucleotide

• Length: 252 bp

>T78462 NZ_CP022110:657324-657575 [Nitrospirillum amazonense CBAmc]
GTGGATATCCACGATTACCTGAACCAGTTCAATTCGGCGGCCGCGCTCAAGCTGGTCAAGTCGCTCCGTGCGCAGGCGCA
AGGGTTGGGTTCTCATCCTCAAAAAGGGCGCCCGGGCCGCATCAACGGTACGCGCGAGTTGGTCATTTCAGGCACGGATT
TCATCATCGCTTACCAAATAGCGGAAACCTGCGTGGATATTCTGGCGGTTCGCCATACCGCTCGTGAATGGCCGGCCCGG
TTGGATCGATAG

Antitoxin

Protein

• Length: 83 a.a.
• Molecular weight: 9094.07 Da
• Isoelectric Point: 4.1196

>AT78462 WP_088870863.1 NZ_CP022110:657040-657288 [Nitrospirillum amazonense CBAmc]
MASQNFSIRTEPAILAELDKLAEAQNRSRNFVVNEAIERYLTEERQWATQVQAGLAAAAAGDFVTDAEMDALFEKFEAAA
DR

Nucleotide

• Length: 249 bp

>AT78462 NZ_CP022110:657040-657288 [Nitrospirillum amazonense CBAmc]
ATGGCCAGCCAGAACTTCTCCATTCGGACCGAGCCCGCCATTCTGGCGGAGTTGGACAAGCTGGCCGAGGCGCAGAACCG
GTCCCGCAATTTCGTGGTCAATGAGGCCATCGAGCGCTATCTCACCGAAGAGCGTCAGTGGGCCACCCAAGTGCAAGCGG
GACTGGCGGCGGCGGCGGCTGGCGACTTCGTCACGGATGCCGAGATGGATGCCTTGTTTGAAAAATTCGAGGCGGCGGCT
GATCGATGA