78461

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) pmenTA/darT(toxin)
Location 443893..445613 Replicon chromosome
Accession NZ_CP022110
Organism Nitrospirillum amazonense CBAmc

Toxin (Protein)


Gene name pmenT Uniprot ID -
Locus tag Y958_RS02215 Protein ID WP_088870737.1
Coordinates 443893..444537 (+) Length 215 a.a.

Antitoxin (Protein)


Gene name pmenA Uniprot ID -
Locus tag Y958_RS02220 Protein ID WP_088870738.1
Coordinates 444537..445613 (+) Length 359 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
Y958_RS02195 439333..439881 + 549 WP_088872427.1 ActR/PrrA/RegA family redox response regulator transcription factor -
Y958_RS02200 439914..441668 - 1755 WP_088870735.1 potassium/proton antiporter -
Y958_RS02205 441885..442340 - 456 WP_088870736.1 DUF488 domain-containing protein -
Y958_RS02210 442456..443568 - 1113 WP_088870575.1 ISAs1 family transposase -
Y958_RS02215 443893..444537 + 645 WP_088870737.1 DUF4433 domain-containing protein Toxin
Y958_RS02220 444537..445613 + 1077 WP_088870738.1 macro domain-containing protein Antitoxin
Y958_RS02225 445850..446050 + 201 WP_004271784.1 50S ribosomal protein L35 -
Y958_RS02230 446064..446426 + 363 WP_040843389.1 50S ribosomal protein L20 -
Y958_RS02235 446690..447766 + 1077 WP_040843390.1 phenylalanine--tRNA ligase subunit alpha -
Y958_RS02240 447833..450226 + 2394 WP_088870739.1 phenylalanine--tRNA ligase subunit beta -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- flank IS/Tn - - 442456..443568 1112


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

ssDNA thymidine ADP-ribosyltransferase, DarT

(13-214)

Antitoxin

Macro domain

(18-130)


Sequences

Toxin        


Download         Length: 215 a.a.        Molecular weight: 23707.05 Da        Isoelectric Point: 7.4805

>T78461 WP_088870737.1 NZ_CP022110:443893-444537 [Nitrospirillum amazonense CBAmc]
VALNLTPERGLLFRITHVSNLPWLLANGLHCANGAANDPNFVAIGNPDLIGKRTHRQVPIPPGGTLADYVPFYFTPKSPM
LFNIKTGYNGIICRSNQEIAILVSSCQIMNSNGVSMLFTDRHAYTATATWSNNHADLQHMIDWDILNRHDFSRNDSYPDK
MERYQAEALAHKHVPPDALLGIGCVSETVKPAIEASVQAASRALQVIVRPGWYF

Download         Length: 645 bp

>T78461 NZ_CP022110:443893-444537 [Nitrospirillum amazonense CBAmc]
GTGGCGCTTAACCTGACCCCGGAGCGGGGCTTATTGTTTCGCATCACCCATGTCTCCAATTTGCCCTGGTTGCTGGCAAA
CGGGCTGCATTGTGCCAATGGCGCTGCCAACGATCCGAATTTCGTTGCTATCGGCAACCCCGACTTGATTGGCAAGCGCA
CCCATCGCCAGGTACCTATCCCTCCCGGCGGAACGTTGGCCGATTACGTTCCCTTTTACTTTACACCGAAATCGCCGATG
CTTTTCAATATCAAGACGGGATACAATGGCATTATCTGCCGCTCCAATCAGGAAATTGCAATCCTAGTCTCATCCTGCCA
GATTATGAATAGCAATGGTGTATCTATGTTGTTCACAGATCGTCACGCCTATACGGCGACGGCGACATGGAGCAATAATC
ATGCCGATCTGCAACACATGATTGACTGGGATATACTCAATCGGCATGACTTTTCTCGCAATGACAGCTATCCCGATAAG
ATGGAACGTTATCAAGCAGAAGCTCTTGCCCATAAGCACGTTCCGCCGGATGCGCTGCTGGGCATCGGCTGCGTGTCGGA
GACGGTAAAGCCCGCTATCGAGGCGAGCGTTCAAGCGGCAAGTCGAGCACTCCAGGTGATCGTTCGTCCAGGGTGGTATT
TCTGA

Antitoxin


Download         Length: 359 a.a.        Molecular weight: 39900.67 Da        Isoelectric Point: 7.8928

>AT78461 WP_088870738.1 NZ_CP022110:444537-445613 [Nitrospirillum amazonense CBAmc]
MIRYTQGNLLAADTQALVNTVNTVGVSGKGIALMFKESYPENFRAYEAVSKAGQLAPGGLFITEREDMLGPRFIVNFATK
KHWRHPSKLEWIEHGLTILREEIKARGIRSIAIPPLGAGNGGLEWNNVKPLIVKALADLDCEVVVYEPTQTYQNVVKRNG
VEKLTPARALMAEMIRRYEVLGFDCSILEAQKLAWFLSGAIQRLSLPNLIADDFVANRYGPYSDKVRHLLDGLDGSYLTC
ERRVADARPFDPIRFQHNRQDRITVYLTSPEANLYRPALDAASKIIDGFQSPHGLELLATVDWLNRESHIALKSDAMMSA
IASWPGPEGAAQRKARVFTQHHVNAAVDHLQSIQSEAT

Download         Length: 1077 bp

>AT78461 NZ_CP022110:444537-445613 [Nitrospirillum amazonense CBAmc]
ATGATTCGCTACACTCAAGGCAATCTGCTCGCAGCCGACACGCAAGCGCTGGTGAACACCGTCAACACGGTGGGCGTTAG
CGGTAAGGGCATCGCACTGATGTTCAAGGAAAGCTACCCTGAAAACTTCCGGGCCTATGAAGCAGTCAGTAAGGCAGGTC
AACTCGCCCCTGGCGGTCTGTTTATCACCGAGCGGGAAGACATGCTCGGTCCGCGCTTCATTGTTAATTTTGCGACCAAG
AAACATTGGCGTCATCCCTCCAAGCTGGAATGGATTGAGCATGGACTGACCATACTTAGGGAGGAGATCAAGGCGCGCGG
CATCCGTTCCATCGCCATTCCGCCACTAGGTGCTGGCAACGGCGGGCTCGAATGGAACAATGTGAAGCCATTGATTGTGA
AGGCACTGGCTGATCTCGATTGTGAGGTCGTCGTCTATGAGCCGACCCAGACCTATCAAAATGTCGTGAAGCGCAACGGC
GTCGAGAAGCTGACTCCAGCGCGGGCGCTAATGGCCGAGATGATCCGGCGCTACGAAGTGCTGGGGTTTGATTGTTCGAT
CCTCGAAGCTCAGAAGCTTGCTTGGTTTCTAAGCGGTGCAATACAGCGTCTGAGCTTGCCCAACCTAATCGCAGACGATT
TCGTAGCCAATCGCTACGGCCCCTATTCGGACAAGGTCCGACACTTGTTGGATGGCTTGGACGGCAGCTACCTGACGTGC
GAGCGCCGGGTAGCGGATGCCCGGCCATTCGACCCAATTCGATTCCAGCACAATCGGCAAGACAGAATAACCGTGTATCT
GACGTCGCCCGAGGCCAACCTTTACCGACCAGCGCTGGACGCCGCTAGCAAGATCATCGACGGATTCCAGTCACCCCATG
GTCTGGAGCTTCTCGCGACGGTTGATTGGCTCAACCGTGAATCGCACATAGCATTGAAAAGTGACGCTATGATGTCAGCT
ATTGCCTCTTGGCCTGGCCCAGAAGGGGCAGCCCAGCGCAAAGCCAGAGTTTTCACACAGCATCATGTGAATGCAGCAGT
CGATCACTTGCAGAGCATTCAATCCGAAGCAACGTAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References