Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relE-parD/RelE(toxin)
Location 169932..170500 Replicon chromosome
Accession NZ_CP022110
Organism Nitrospirillum amazonense CBAmc

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag Y958_RS00835 Protein ID WP_088870526.1
Coordinates 169932..170213 (-) Length 94 a.a.

Antitoxin (Protein)


Gene name parD Uniprot ID -
Locus tag Y958_RS00840 Protein ID WP_088870527.1
Coordinates 170210..170500 (-) Length 97 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
Y958_RS00810 165498..166760 - 1263 WP_088870523.1 tRNA guanosine(34) transglycosylase Tgt -
Y958_RS00815 166796..167596 - 801 WP_050898374.1 queuosine precursor transporter -
Y958_RS00820 167755..168051 - 297 WP_040846783.1 50S ribosomal protein L28 -
Y958_RS00825 168323..168817 - 495 WP_088870524.1 hypothetical protein -
Y958_RS00830 168820..169845 - 1026 WP_088870525.1 methylmalonyl Co-A mutase-associated GTPase MeaB -
Y958_RS00835 169932..170213 - 282 WP_088870526.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
Y958_RS00840 170210..170500 - 291 WP_088870527.1 hypothetical protein Antitoxin
Y958_RS00845 170549..172441 - 1893 WP_088870528.1 ABC transporter ATP-binding protein/permease -
Y958_RS31165 172537..172812 - 276 WP_186291207.1 hypothetical protein -
Y958_RS00855 172860..174617 - 1758 WP_145728003.1 PAS domain-containing sensor histidine kinase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 149250..170500 21250


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(2-81)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 94 a.a.        Molecular weight: 10344.19 Da        Isoelectric Point: 11.3796

>T78460 WP_088870526.1 NZ_CP022110:c170213-169932 [Nitrospirillum amazonense CBAmc]
VKLIWARPSAADRRAIRDYIAQENPAAALALDELFSEKALLLTKHPGIGRPGRIVGTRELVIQRNYILIYRVIGGVVRVL
GLVHAARQWPPTP

Download         Length: 282 bp

>T78460 NZ_CP022110:c170213-169932 [Nitrospirillum amazonense CBAmc]
GTGAAGCTGATTTGGGCACGTCCATCAGCCGCTGACCGCAGGGCAATCCGTGATTACATCGCACAGGAAAACCCGGCCGC
CGCGCTGGCGTTGGATGAGCTGTTTTCAGAAAAGGCCCTGCTTTTGACCAAGCATCCTGGCATCGGCCGGCCAGGACGTA
TCGTCGGTACGCGCGAATTGGTCATACAGCGGAACTACATATTGATCTATCGCGTGATCGGCGGCGTCGTACGGGTGTTG
GGTCTTGTGCATGCGGCGCGCCAATGGCCGCCGACCCCATAG

Antitoxin


Download         Length: 97 a.a.        Molecular weight: 10764.94 Da        Isoelectric Point: 4.4617

>AT78460 WP_088870527.1 NZ_CP022110:c170500-170210 [Nitrospirillum amazonense CBAmc]
MTETTFTFRVDEALKAAFAEAAKTNDRTGAQLLRDYMRDFVRKQQETADYDAWFRAKVQAGIDADDAGDVLSAEEVEAEA
ETWRAAMRRKLVGPAS

Download         Length: 291 bp

>AT78460 NZ_CP022110:c170500-170210 [Nitrospirillum amazonense CBAmc]
ATGACCGAAACGACCTTCACTTTCCGGGTGGATGAAGCCCTGAAAGCCGCGTTCGCTGAAGCCGCCAAAACCAATGATCG
CACCGGTGCGCAATTGCTCCGGGATTACATGCGCGATTTCGTGCGAAAGCAGCAGGAAACCGCGGACTACGACGCCTGGT
TCCGAGCCAAGGTGCAGGCCGGTATTGATGCTGACGACGCAGGTGACGTGCTGTCGGCTGAAGAAGTGGAGGCCGAAGCC
GAAACCTGGCGGGCGGCGATGCGGCGCAAGCTGGTTGGTCCAGCGTCGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References