Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/YafQ-RelB
Location 458471..459011 Replicon chromosome
Accession NZ_CP022104
Organism Vibrio anguillarum strain CNEVA NB11008

Toxin (Protein)


Gene name relE Uniprot ID A0A7Y3QIZ2
Locus tag CEQ50_RS16600 Protein ID WP_039428600.1
Coordinates 458471..458740 (-) Length 90 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A1T4SKS5
Locus tag CEQ50_RS16605 Protein ID WP_032480862.1
Coordinates 458733..459011 (-) Length 93 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CEQ50_RS16565 453572..454252 + 681 WP_198300524.1 hypothetical protein -
CEQ50_RS16570 454427..455527 + 1101 WP_088733278.1 hypothetical protein -
CEQ50_RS16580 456224..456472 + 249 WP_026028286.1 DUF3297 family protein -
CEQ50_RS16585 456701..457339 + 639 WP_088733279.1 hypothetical protein -
CEQ50_RS16590 457518..458336 + 819 WP_157724329.1 DUF2971 domain-containing protein -
CEQ50_RS16600 458471..458740 - 270 WP_039428600.1 type II toxin-antitoxin system YafQ family toxin Toxin
CEQ50_RS16605 458733..459011 - 279 WP_032480862.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
CEQ50_RS16615 459809..460780 + 972 WP_088733281.1 immunity 49 family protein -
CEQ50_RS19980 460764..460976 + 213 WP_157724337.1 DUF3265 domain-containing protein -
CEQ50_RS16625 461034..461282 + 249 WP_026028286.1 DUF3297 family protein -
CEQ50_RS16630 461520..462302 + 783 WP_088733282.1 hypothetical protein -
CEQ50_RS16635 462463..463233 + 771 WP_088729508.1 alpha/beta hydrolase -
CEQ50_RS16640 463516..463800 + 285 WP_088733598.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Integron - - 416630..557447 140817


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, YafQ-like toxin

(2-89)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(1-85)


Sequences

Toxin        


Download         Length: 90 a.a.        Molecular weight: 10250.91 Da        Isoelectric Point: 8.9357

>T78447 WP_039428600.1 NZ_CP022104:c458740-458471 [Vibrio anguillarum]
MYSLEYSTQFKKDFKKITKMPISDIIEVGNIISKLQRGEKLDPKNVDHPLTGGWVGFRDCHVKPDLVLIYRIFDGQLQLA
RIGSHSDLF

Download         Length: 270 bp

>T78447 NZ_CP022104:c458740-458471 [Vibrio anguillarum]
ATGTATAGCTTAGAATACTCAACACAATTCAAAAAAGACTTCAAAAAAATCACCAAAATGCCGATTTCGGACATCATTGA
AGTCGGCAACATCATATCAAAGCTACAAAGAGGCGAAAAACTCGACCCTAAAAATGTTGATCACCCTTTAACTGGCGGAT
GGGTTGGATTCCGTGACTGTCACGTTAAACCAGATCTAGTGCTCATTTATCGCATTTTTGATGGCCAGCTCCAGTTAGCA
AGAATTGGCTCTCATAGTGATTTGTTCTGA

Antitoxin


Download         Length: 93 a.a.        Molecular weight: 10053.51 Da        Isoelectric Point: 6.0643

>AT78447 WP_032480862.1 NZ_CP022104:c459011-458733 [Vibrio anguillarum]
MRTEMLSTRIDHDTKVAFTSICDEMGLSTSQAIKIFAKAVINHGGIPFDLRVPQPNETTISAMNELVQGHGHKAESVDAM
LTELTEGKVKNV

Download         Length: 279 bp

>AT78447 NZ_CP022104:c459011-458733 [Vibrio anguillarum]
ATGAGAACAGAAATGCTAAGTACTCGCATAGACCATGATACCAAAGTTGCTTTTACTAGCATCTGTGACGAAATGGGTCT
TAGTACATCACAAGCTATTAAAATTTTTGCAAAAGCCGTGATTAATCATGGTGGTATTCCATTTGACTTACGTGTGCCTC
AACCAAATGAAACAACGATTTCTGCAATGAATGAACTTGTTCAAGGCCATGGGCATAAAGCAGAATCTGTTGACGCTATG
CTTACTGAGCTAACTGAAGGCAAAGTTAAGAATGTATAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A7Y3QIZ2

Antitoxin

Source ID Structure
AlphaFold DB A0A1T4SKS5

References