Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PanAT/DUF4065(antitoxin)
Location 173419..175106 Replicon chromosome
Accession NZ_CP022103
Organism Vibrio anguillarum strain CNEVA NB11008

Toxin (Protein)


Gene name panT Uniprot ID -
Locus tag CEQ50_RS00865 Protein ID WP_088731417.1
Coordinates 173883..175106 (+) Length 408 a.a.

Antitoxin (Protein)


Gene name panA Uniprot ID -
Locus tag CEQ50_RS00860 Protein ID WP_005378671.1
Coordinates 173419..173886 (+) Length 156 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CEQ50_RS00830 168619..168840 - 222 WP_005378664.1 AlpA family transcriptional regulator -
CEQ50_RS00835 168918..169907 + 990 WP_088731409.1 50S ribosome-binding GTPase -
CEQ50_RS00840 170018..170464 + 447 WP_088731411.1 hypothetical protein -
CEQ50_RS00845 170505..171146 - 642 WP_088731413.1 inovirus Gp2 family protein -
CEQ50_RS00850 171313..172350 - 1038 WP_088731415.1 hypothetical protein -
CEQ50_RS00855 172495..173165 + 671 Protein_162 hypothetical protein -
CEQ50_RS00860 173419..173886 + 468 WP_005378671.1 DUF4065 domain-containing protein Antitoxin
CEQ50_RS00865 173883..175106 + 1224 WP_088731417.1 RelA/SpoT domain-containing protein Toxin
CEQ50_RS00870 175297..176406 - 1110 WP_029388281.1 tRNA (uridine(54)-C5)-methyltransferase TrmA -
CEQ50_RS00875 176757..178166 + 1410 WP_000572558.1 site-specific integrase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

RelA/SpoT

(111-228)

Antitoxin

Antitoxin SocA-like, Panacea domain

(32-123)


Sequences

Toxin        


Download         Length: 408 a.a.        Molecular weight: 45947.69 Da        Isoelectric Point: 5.2469

>T78446 WP_088731417.1 NZ_CP022103:173883-175106 [Vibrio anguillarum]
VSNKENSVVSFYIDDTPTAEQASKTFQDDYELDFQDFIERTVNESAAEDFSYSNNGVKKAGRRLRKREGDLKSATATIQQ
FRAAHEKPLNTIAYLVGRCCRELGIDVKPVTRLKRLETIVDKLQRKSLDGETANATCVTNMNDIGGCRAIFPDLISLEKV
QSQLQLTVEKVGRVRIKDIDDYITSPKPNDCGYRSLHVIYRYDHASGKSFNIEAQLRTRLQHLWATTVEIVDILEGTKIK
THSHSSNEDKSSLQIQWEELLSIMSQYIADAEGAIELSDIDKANFSKRLIVLDREINALNRLSSFKILSEKVNSCCDNSI
EHVLLVINETSRELIFSEEFENYSQAISVYNAAEKVTRSYSRSTSRLNTLLISTKNMGQLSEAYPNYLGDCASFITLLED
AMLSGES

Download         Length: 1224 bp

>T78446 NZ_CP022103:173883-175106 [Vibrio anguillarum]
GTGAGTAACAAAGAAAATAGTGTTGTCAGTTTTTACATTGACGACACTCCTACCGCAGAGCAAGCTTCAAAAACCTTCCA
AGACGACTACGAGCTGGACTTTCAGGATTTTATAGAAAGAACGGTAAATGAAAGTGCTGCTGAAGACTTCTCGTACTCAA
ATAATGGAGTAAAGAAAGCTGGAAGACGGCTGCGCAAGAGAGAGGGCGACCTCAAGTCAGCTACTGCTACAATCCAACAG
TTTCGAGCCGCACACGAAAAGCCATTAAACACTATCGCATATCTTGTTGGTCGCTGTTGCCGGGAACTGGGTATAGATGT
AAAACCAGTTACACGGTTAAAGCGTTTAGAAACAATCGTAGATAAGTTGCAGCGTAAATCTCTTGATGGTGAAACGGCAA
ATGCTACTTGTGTGACCAATATGAATGATATTGGCGGTTGCAGGGCGATTTTCCCGGATTTAATTTCCTTGGAGAAGGTG
CAATCTCAACTGCAACTTACCGTTGAAAAGGTAGGCCGAGTTAGAATCAAAGATATTGACGATTATATTACTAGCCCTAA
GCCTAATGATTGTGGTTACCGAAGCTTGCATGTGATTTATCGCTATGACCATGCTAGCGGTAAAAGTTTTAACATTGAGG
CTCAGCTACGTACTCGACTTCAACATCTTTGGGCAACTACTGTGGAAATTGTCGACATCCTGGAAGGCACCAAGATTAAG
ACTCACTCTCACAGTTCAAATGAAGATAAGAGCAGTTTACAGATTCAATGGGAAGAATTGCTTTCGATCATGAGCCAGTA
CATTGCTGATGCTGAAGGGGCTATAGAGCTAAGTGATATCGATAAAGCCAATTTTTCAAAGCGCTTGATCGTCTTGGACC
GCGAAATCAATGCGCTGAATCGATTGAGTAGTTTTAAAATTTTATCTGAAAAGGTGAATTCTTGCTGTGATAACTCTATT
GAGCACGTATTGCTAGTTATTAACGAAACCTCACGAGAATTGATCTTTAGTGAAGAGTTTGAAAATTACAGTCAGGCAAT
TTCAGTTTACAACGCGGCTGAGAAAGTCACTCGTAGCTACTCAAGATCAACCTCGAGACTCAATACCCTTCTCATCTCCA
CAAAAAATATGGGGCAACTTTCGGAAGCCTACCCTAACTATCTAGGTGATTGTGCCTCATTCATCACTCTGCTTGAAGAC
GCAATGCTTTCTGGTGAAAGTTAA

Antitoxin


Download         Length: 156 a.a.        Molecular weight: 17516.97 Da        Isoelectric Point: 7.9061

>AT78446 WP_005378671.1 NZ_CP022103:173419-173886 [Vibrio anguillarum]
MKAYHTYSAVDVAWSLLKHAKEQGKCFSNLQLQKLTYVCHGLSLAHFQRPLVVDDVFAWKFGPVVPSVYFRFKSYGSSVI
TEQCDVALDQESESIVKDVVSKLGHLTGPQLVDLTHREGSPWHQVWDGTHQKVIPDHLIQAHYTQIKQSGRTASL

Download         Length: 468 bp

>AT78446 NZ_CP022103:173419-173886 [Vibrio anguillarum]
ATGAAAGCATATCACACATACAGTGCTGTAGACGTTGCATGGAGCTTGCTCAAGCATGCGAAAGAGCAAGGTAAATGCTT
CTCCAATTTGCAGCTACAAAAACTTACCTATGTTTGTCATGGTTTATCATTGGCGCATTTCCAGCGTCCTCTCGTCGTAG
ATGATGTATTTGCTTGGAAGTTTGGTCCAGTGGTGCCATCTGTTTACTTCCGCTTTAAATCTTACGGTAGTAGTGTGATC
ACTGAACAATGTGATGTAGCACTAGACCAAGAAAGTGAGTCTATTGTCAAAGATGTTGTATCTAAACTGGGCCATTTGAC
GGGGCCTCAACTTGTAGATTTAACTCACCGAGAGGGAAGTCCATGGCATCAGGTATGGGATGGCACACACCAAAAAGTGA
TTCCGGATCATTTGATTCAAGCCCATTACACTCAAATCAAACAATCCGGACGAACAGCTAGCCTGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References