Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) TsdAT/-
Location 924903..925415 Replicon chromosome
Accession NZ_CP022096
Organism Staphylococcus pettenkoferi strain FDAARGOS_288

Toxin (Protein)


Gene name TsdT Uniprot ID -
Locus tag CEP67_RS04405 Protein ID WP_002471114.1
Coordinates 924903..925109 (-) Length 69 a.a.

Antitoxin (Protein)


Gene name TsdA Uniprot ID -
Locus tag CEP67_RS04410 Protein ID WP_049405729.1
Coordinates 925131..925415 (-) Length 95 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CEP67_RS04385 920333..921697 - 1365 WP_002471093.1 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase -
CEP67_RS04390 921709..922779 - 1071 WP_002471090.1 D-alanine--D-alanine ligase -
CEP67_RS04395 923006..924199 + 1194 WP_002471106.1 rod shape-determining protein RodA -
CEP67_RS04400 924497..924637 - 141 WP_088606361.1 hypothetical protein -
CEP67_RS04405 924903..925109 - 207 WP_002471114.1 hypothetical protein Toxin
CEP67_RS04410 925131..925415 - 285 WP_049405729.1 copper-sensing transcriptional repressor CsoR Antitoxin
CEP67_RS04415 925575..927047 + 1473 WP_088606653.1 cardiolipin synthase -
CEP67_RS04420 927097..927774 + 678 WP_002471110.1 HD domain-containing protein -
CEP67_RS04425 927914..928780 - 867 WP_049405723.1 membrane protein insertase YidC -
CEP67_RS04430 928860..929507 - 648 WP_002471096.1 thiamine phosphate synthase -
CEP67_RS04435 929507..930298 - 792 WP_040806045.1 hydroxyethylthiazole kinase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Metal-sensitive transcriptional repressor

(11-89)


Sequences

Toxin        


Download         Length: 69 a.a.        Molecular weight: 7578.49 Da        Isoelectric Point: 3.9936

>T78424 WP_002471114.1 NZ_CP022096:c925109-924903 [Staphylococcus pettenkoferi]
METKHVYTETISTQDQIEELKHILSDMIGVSEVDIDGAKGGITITFETPANLNAIEKEIYDAGYTILY

Download         Length: 207 bp

>T78424 NZ_CP022096:c925109-924903 [Staphylococcus pettenkoferi]
ATGGAAACTAAACATGTTTATACAGAAACCATTTCTACGCAAGATCAAATCGAAGAATTAAAGCACATCTTATCTGATAT
GATTGGTGTGAGTGAGGTAGATATTGACGGTGCGAAAGGGGGTATTACGATTACCTTTGAAACGCCTGCGAATTTGAATG
CGATTGAGAAAGAAATTTATGATGCAGGTTACACGATTCTTTATTAA

Antitoxin


Download         Length: 95 a.a.        Molecular weight: 10837.37 Da        Isoelectric Point: 6.4786

>AT78424 WP_049405729.1 NZ_CP022096:c925415-925131 [Staphylococcus pettenkoferi]
MDRAHHSEQTKANLKSRLNRIEGQVRAINRMIDEDVYCDDVLTQIRATRSALNSVATQLLDHHMKGCILNKVNKGEEEEA
MEELLVTFQKLMKD

Download         Length: 285 bp

>AT78424 NZ_CP022096:c925415-925131 [Staphylococcus pettenkoferi]
ATGGACCGTGCGCATCATTCTGAACAGACCAAAGCAAATTTGAAGTCTCGATTAAATCGGATTGAAGGACAAGTGAGAGC
CATTAATCGCATGATTGATGAAGATGTCTATTGTGATGATGTTCTCACACAAATTAGAGCAACACGTTCAGCGTTAAATA
GTGTTGCCACGCAATTGTTAGACCATCACATGAAAGGTTGCATTCTGAACAAAGTGAATAAAGGTGAAGAAGAGGAAGCG
ATGGAAGAACTGCTCGTCACATTTCAGAAATTGATGAAAGATTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References