Detailed information of TA system TA078406

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): parDE/ParE-YefM
• Location: 4013594..4014144
• Replicon: chromosome
• Accession: NZ_CP022089
• Organism: Shewanella sp. FDAARGOS_354

Toxin (Protein)

• Gene name: parE
• Uniprot ID: -
• Locus tag: CEQ32_RS18070
• Protein ID: WP_088586540.1
• Coordinates: 4013594..4013893 (-)
• Length: 100 a.a.

Antitoxin (Protein)

• Gene name: parD
• Uniprot ID: -
• Locus tag: CEQ32_RS18075
• Protein ID: WP_011621139.1
• Coordinates: 4013902..4014144 (-)
• Length: 81 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
CEQ32_RS18070	4013594..4013893	-	300	WP_088586540.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
CEQ32_RS18075	4013902..4014144	-	243	WP_011621139.1	type II toxin-antitoxin system Phd/YefM family antitoxin	Antitoxin
CEQ32_RS18080	4014339..4015082	-	744	WP_088586541.1	hypothetical protein	-
CEQ32_RS18085	4015093..4016355	-	1263	WP_055647370.1	beta-ketoacyl-ACP synthase	-
CEQ32_RS18090	4016356..4017081	-	726	WP_055647371.1	3-ketoacyl-ACP reductase FabG2	-
CEQ32_RS18095	4017182..4017724	-	543	WP_055647372.1	hotdog family protein	-
CEQ32_RS18100	4017730..4018947	-	1218	WP_055647373.1	beta-ketoacyl-[acyl-carrier-protein] synthase family protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (6-90)

Antitoxin

• Type II toxin-antitoxin system, antitoxin Phd/YefM (1-64)

Sequences

Toxin

Protein

• Length: 100 a.a.
• Molecular weight: 11552.35 Da
• Isoelectric Point: 10.0231

>T78406 WP_088586540.1 NZ_CP022089:c4013893-4013594 [Shewanella sp. FDAARGOS_354]
MNNKRYKLSRLAQAHLLKIKDYTLQHFSESQWHKYKQSLISGLQMLANHPGLGRSCNDIYPNGFYFPIGKHTAYFTKEDD
FILIVALLGQPQLPQHHLK

Nucleotide

• Length: 300 bp

>T78406 NZ_CP022089:c4013893-4013594 [Shewanella sp. FDAARGOS_354]
ATGAATAATAAACGCTATAAACTGAGTAGGTTAGCTCAGGCTCACCTACTAAAGATTAAAGACTACACCCTTCAACACTT
TTCTGAGTCGCAGTGGCACAAATACAAACAAAGCCTAATATCCGGCTTGCAAATGTTAGCCAATCACCCCGGATTAGGCA
GAAGCTGCAACGATATTTACCCCAACGGTTTCTACTTTCCTATCGGTAAACACACAGCCTACTTCACCAAAGAAGACGAC
TTTATCCTTATCGTTGCCCTGTTAGGTCAACCACAACTACCCCAACATCATCTGAAATAG

Antitoxin

Protein

• Length: 81 a.a.
• Molecular weight: 8954.18 Da
• Isoelectric Point: 5.0621

>AT78406 WP_011621139.1 NZ_CP022089:c4014144-4013902 [Shewanella sp. FDAARGOS_354]
MQTLTANDAKRNFGELLLNAQREPIKISKNSKDAVVVMSIHDYEQLEAMKADYLKHCFNAAKEDLAKGNVVDGEDFLNAL

Nucleotide

• Length: 243 bp

>AT78406 NZ_CP022089:c4014144-4013902 [Shewanella sp. FDAARGOS_354]
ATGCAAACATTAACCGCCAATGACGCCAAACGAAATTTCGGTGAGTTGCTGCTAAACGCTCAACGTGAACCCATCAAGAT
CAGCAAAAACAGTAAAGATGCGGTTGTGGTTATGTCTATCCACGATTACGAACAGCTTGAGGCGATGAAAGCCGACTATC
TGAAGCACTGTTTCAACGCAGCCAAAGAAGATTTAGCGAAGGGCAATGTGGTAGATGGCGAAGATTTTCTTAACGCCCTG
TAG