78404

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) parDE/ParE-YefM
Location 1012499..1013070 Replicon chromosome
Accession NZ_CP022089
Organism Shewanella sp. FDAARGOS_354

Toxin (Protein)


Gene name parE Uniprot ID A0A2I8S8S5
Locus tag CEQ32_RS04635 Protein ID WP_011918375.1
Coordinates 1012499..1012810 (-) Length 104 a.a.

Antitoxin (Protein)


Gene name parD Uniprot ID A0A1Z3MW28
Locus tag CEQ32_RS04640 Protein ID WP_011787805.1
Coordinates 1012810..1013070 (-) Length 87 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CEQ32_RS04625 1008889..1009341 + 453 Protein_875 family 43 glycosylhydrolase -
CEQ32_RS04630 1009395..1012475 - 3081 WP_088585589.1 Tn3 family transposase -
CEQ32_RS04635 1012499..1012810 - 312 WP_011918375.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
CEQ32_RS04640 1012810..1013070 - 261 WP_011787805.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
CEQ32_RS04645 1013240..1013860 + 621 WP_011787804.1 recombinase family protein -
CEQ32_RS04650 1013978..1014310 - 333 WP_011787803.1 TraR/DksA C4-type zinc finger protein -
CEQ32_RS04655 1014401..1015255 - 855 WP_011787802.1 universal stress protein -
CEQ32_RS04660 1015290..1016780 - 1491 WP_011787801.1 SulP family inorganic anion transporter -
CEQ32_RS04665 1017275..1017790 + 516 Protein_883 family 43 glycosylhydrolase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(6-92)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-61)


Sequences

Toxin        


Download         Length: 104 a.a.        Molecular weight: 11862.70 Da        Isoelectric Point: 8.5341

>T78404 WP_011918375.1 NZ_CP022089:c1012810-1012499 [Shewanella sp. FDAARGOS_354]
MPVTYHLTPDAQSDLIGIHRFTLAQWGTTQSKTYLSGLRQTIQLLAETPTLGKNRPEVRMNVFSFPYSSHVIYYIQHEHQ
FVVFGILHKSMVPLAHLAEREII

Download         Length: 312 bp

>T78404 NZ_CP022089:c1012810-1012499 [Shewanella sp. FDAARGOS_354]
ATGCCGGTAACTTATCATTTAACGCCCGATGCACAATCTGATCTGATAGGTATTCACCGCTTTACGTTAGCCCAATGGGG
AACGACTCAGTCGAAGACCTATTTATCAGGACTTAGACAAACGATTCAACTGCTGGCTGAAACACCCACCCTTGGGAAAA
ATAGACCCGAGGTACGCATGAATGTGTTTAGCTTCCCTTATTCAAGTCATGTCATCTATTACATCCAACATGAGCATCAA
TTCGTTGTATTTGGGATCTTACATAAAAGTATGGTTCCACTTGCACATCTCGCGGAGCGGGAAATTATTTGA

Antitoxin


Download         Length: 87 a.a.        Molecular weight: 9312.71 Da        Isoelectric Point: 6.4546

>AT78404 WP_011787805.1 NZ_CP022089:c1013070-1012810 [Shewanella sp. FDAARGOS_354]
MNTLSANEAKIHFGDLLLKAQQAPIQINKNGKPVAVVISADAYQSIETLKLHLLQSKAVKAITDIKMGNLVDGNTFFDEL
AAGQYD

Download         Length: 261 bp

>AT78404 NZ_CP022089:c1013070-1012810 [Shewanella sp. FDAARGOS_354]
ATGAACACTCTTTCAGCCAATGAAGCAAAAATTCACTTTGGAGATTTGTTGCTCAAAGCTCAACAAGCTCCAATCCAAAT
TAATAAAAATGGCAAGCCTGTGGCCGTTGTTATTTCAGCTGATGCATACCAAAGTATCGAGACACTAAAATTACATTTGC
TTCAATCCAAAGCGGTGAAAGCCATAACTGACATCAAAATGGGCAATTTGGTTGATGGTAATACCTTTTTTGATGAGCTG
GCCGCAGGGCAGTATGACTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2I8S8S5

Antitoxin

Source ID Structure
AlphaFold DB A0A1Z3MW28

References