Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | VII | Classification (family/domain) | HepT-MntA/HepT(toxin) |
Location | 173563..174379 | Replicon | chromosome |
Accession | NZ_CP022089 | ||
Organism | Shewanella sp. FDAARGOS_354 |
Toxin (Protein)
Gene name | hepT | Uniprot ID | A0A252EQR5 |
Locus tag | CEQ32_RS00885 | Protein ID | WP_069455295.1 |
Coordinates | 173563..173964 (-) | Length | 134 a.a. |
Antitoxin (Protein)
Gene name | mntA | Uniprot ID | A0A501X4H4 |
Locus tag | CEQ32_RS00890 | Protein ID | WP_069455294.1 |
Coordinates | 173957..174379 (-) | Length | 141 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
CEQ32_RS00865 | 168632..168922 | + | 291 | WP_052184036.1 | transposase | - |
CEQ32_RS00870 | 168943..170352 | - | 1410 | WP_088585341.1 | ammonia-forming cytochrome c nitrite reductase subunit c552 | - |
CEQ32_RS00875 | 170336..171547 | - | 1212 | WP_088585342.1 | NnrS family protein | - |
CEQ32_RS00880 | 172338..173369 | + | 1032 | WP_088585343.1 | dTDP-glucose 4,6-dehydratase | - |
CEQ32_RS00885 | 173563..173964 | - | 402 | WP_069455295.1 | type II toxin-antitoxin system toxin | Toxin |
CEQ32_RS00890 | 173957..174379 | - | 423 | WP_069455294.1 | type II toxin-antitoxin system antitoxin | Antitoxin |
CEQ32_RS00895 | 174486..175253 | - | 768 | WP_086904479.1 | HutD family protein | - |
CEQ32_RS00900 | 175529..175975 | - | 447 | WP_192959140.1 | copper resistance protein NlpE | - |
CEQ32_RS00905 | 176149..177357 | + | 1209 | WP_001206290.1 | IS4-like element IS10A family transposase | - |
CEQ32_RS00910 | 177703..179064 | + | 1362 | WP_088585345.1 | GAF domain-containing sensor histidine kinase | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|---|---|---|---|---|---|---|
- | flank | IS/Tn | - | - | 176149..177357 | 1208 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 134 a.a. Molecular weight: 15296.57 Da Isoelectric Point: 6.3185
>T78403 WP_069455295.1 NZ_CP022089:c173964-173563 [Shewanella sp. FDAARGOS_354]
MNDIIINKIATIKRCIKRIQQVYGDGSQFKQDFTLQDSVILNLQRCCEACIDIANHINRQQQLGIPQSSRDSFTLLAQNN
LITQPLADNLKKMVGLRNIAVHDYQELNLDIVVHVVQHHLEDFEQFIDVIKAE
MNDIIINKIATIKRCIKRIQQVYGDGSQFKQDFTLQDSVILNLQRCCEACIDIANHINRQQQLGIPQSSRDSFTLLAQNN
LITQPLADNLKKMVGLRNIAVHDYQELNLDIVVHVVQHHLEDFEQFIDVIKAE
Download Length: 402 bp
>T78403 NZ_CP022089:c173964-173563 [Shewanella sp. FDAARGOS_354]
TTGAATGACATTATTATCAATAAAATAGCCACCATCAAACGCTGTATAAAGCGCATCCAACAAGTCTATGGTGATGGAAG
CCAGTTCAAACAAGACTTCACCTTGCAAGATAGCGTTATCCTCAATTTACAACGCTGCTGCGAAGCCTGTATCGACATAG
CCAATCATATTAACCGCCAACAACAACTAGGCATCCCCCAAAGTAGCCGTGATAGCTTTACATTACTCGCACAAAATAAC
CTTATTACTCAGCCACTCGCAGATAACTTAAAGAAAATGGTCGGCCTGCGAAACATCGCAGTACATGACTACCAAGAACT
CAACCTTGATATCGTTGTCCATGTTGTACAGCATCATCTTGAGGATTTTGAGCAATTTATTGATGTGATAAAAGCAGAGT
GA
TTGAATGACATTATTATCAATAAAATAGCCACCATCAAACGCTGTATAAAGCGCATCCAACAAGTCTATGGTGATGGAAG
CCAGTTCAAACAAGACTTCACCTTGCAAGATAGCGTTATCCTCAATTTACAACGCTGCTGCGAAGCCTGTATCGACATAG
CCAATCATATTAACCGCCAACAACAACTAGGCATCCCCCAAAGTAGCCGTGATAGCTTTACATTACTCGCACAAAATAAC
CTTATTACTCAGCCACTCGCAGATAACTTAAAGAAAATGGTCGGCCTGCGAAACATCGCAGTACATGACTACCAAGAACT
CAACCTTGATATCGTTGTCCATGTTGTACAGCATCATCTTGAGGATTTTGAGCAATTTATTGATGTGATAAAAGCAGAGT
GA
Antitoxin
Download Length: 141 a.a. Molecular weight: 15795.88 Da Isoelectric Point: 5.1520
>AT78403 WP_069455294.1 NZ_CP022089:c174379-173957 [Shewanella sp. FDAARGOS_354]
MQQLNEKKIIKLLRDNIPKLQLIYLFGSYSQGTQHRNSDIDIAVLAADTLDNIARWELAQKLASALDSDVDLVDLRSAST
VLCQQVVTQGKQLWGTQQDDELFAVKTISMYQHLQAERQAIIDDVMANTAAKDHRGSHFE
MQQLNEKKIIKLLRDNIPKLQLIYLFGSYSQGTQHRNSDIDIAVLAADTLDNIARWELAQKLASALDSDVDLVDLRSAST
VLCQQVVTQGKQLWGTQQDDELFAVKTISMYQHLQAERQAIIDDVMANTAAKDHRGSHFE
Download Length: 423 bp
>AT78403 NZ_CP022089:c174379-173957 [Shewanella sp. FDAARGOS_354]
ATGCAACAACTAAATGAAAAGAAAATCATAAAGTTACTGCGAGACAACATCCCAAAGTTGCAATTAATCTACCTGTTTGG
CTCTTATTCGCAGGGAACACAACACCGCAACAGCGATATCGATATCGCGGTACTCGCCGCTGACACTTTAGACAATATTG
CACGCTGGGAACTTGCCCAAAAACTCGCTTCGGCGTTGGACTCAGATGTTGATCTGGTTGATTTACGCTCAGCATCCACA
GTGTTATGCCAACAGGTAGTCACTCAAGGGAAGCAACTTTGGGGAACACAACAAGATGATGAACTTTTTGCCGTAAAGAC
CATCTCAATGTACCAACATCTACAAGCCGAAAGACAGGCAATTATTGATGATGTAATGGCCAACACCGCAGCCAAAGATC
ATAGGGGGAGTCACTTTGAATGA
ATGCAACAACTAAATGAAAAGAAAATCATAAAGTTACTGCGAGACAACATCCCAAAGTTGCAATTAATCTACCTGTTTGG
CTCTTATTCGCAGGGAACACAACACCGCAACAGCGATATCGATATCGCGGTACTCGCCGCTGACACTTTAGACAATATTG
CACGCTGGGAACTTGCCCAAAAACTCGCTTCGGCGTTGGACTCAGATGTTGATCTGGTTGATTTACGCTCAGCATCCACA
GTGTTATGCCAACAGGTAGTCACTCAAGGGAAGCAACTTTGGGGAACACAACAAGATGATGAACTTTTTGCCGTAAAGAC
CATCTCAATGTACCAACATCTACAAGCCGAAAGACAGGCAATTATTGATGATGTAATGGCCAACACCGCAGCCAAAGATC
ATAGGGGGAGTCACTTTGAATGA
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Structures
Toxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A252EQR5 |
Antitoxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A501X4H4 |