Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 3750157..3750297 Replicon chromosome
Accession NZ_CP022073
Organism Citrobacter koseri strain FDAARGOS_287

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 3750192..3750295 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 3750157..3750297 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CEP66_RS18330 3746613..3747275 - 663 WP_012132019.1 exodeoxyribonuclease X -
CEP66_RS18335 3747299..3747955 - 657 WP_024130258.1 carbon-nitrogen hydrolase family protein -
CEP66_RS18340 3748061..3748291 - 231 WP_024130259.1 DNA polymerase III subunit theta -
CEP66_RS18345 3748432..3748806 + 375 WP_012132022.1 CopC domain-containing protein YobA -
CEP66_RS18350 3748806..3749681 + 876 WP_077956859.1 copper homeostasis membrane protein CopD -
CEP66_RS18355 3749698..3750036 + 339 WP_012132024.1 YebY family protein -
- 3750157..3750297 - 141 - - Antitoxin
- 3750192..3750295 + 104 - - Toxin
CEP66_RS18365 3750425..3751504 - 1080 WP_060816000.1 phage integrase Arm DNA-binding domain-containing protein -
CEP66_RS18370 3751479..3751751 - 273 WP_060816001.1 excisionase -
CEP66_RS18375 3751813..3752052 - 240 WP_060816002.1 DUF4060 family protein -
CEP66_RS18380 3752060..3752332 - 273 WP_060816003.1 hypothetical protein -
CEP66_RS18385 3752322..3752930 - 609 WP_060816004.1 hypothetical protein -
CEP66_RS18390 3752923..3753267 - 345 WP_060816005.1 hypothetical protein -
CEP66_RS18395 3753302..3754411 - 1110 WP_060816006.1 recombinase RecT -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 3744556..3805498 60942


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T78348 NZ_CP022073:3750192-3750295 [Citrobacter koseri]
GGCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 141 bp

>AT78348 NZ_CP022073:c3750297-3750157 [Citrobacter koseri]
ATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGC
ATTAATGCAGGCTAAGTCGCCTTGCCCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References