Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) parDE/RelE-RHH
Location 18340..18887 Replicon plasmid unnamed4
Accession NZ_CP022064
Organism Salmonella enterica subsp. enterica serovar Typhimurium var. 5- strain FDAARGOS_312

Toxin (Protein)


Gene name parE Uniprot ID W0LWB3
Locus tag CEP90_RS26505 Protein ID WP_000970007.1
Coordinates 18606..18887 (+) Length 94 a.a.

Antitoxin (Protein)


Gene name parD Uniprot ID E1QMW3
Locus tag CEP90_RS26500 Protein ID WP_000079941.1
Coordinates 18340..18609 (+) Length 90 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CEP90_RS26455 13984..14517 - 534 WP_001303319.1 transcription termination factor NusG -
CEP90_RS26465 14959..15246 - 288 WP_000074849.1 conjugal transfer protein TraA -
CEP90_RS26470 15164..15427 - 264 WP_001324596.1 ash family protein -
CEP90_RS26485 16400..17431 + 1032 WP_000907873.1 replication initiation protein -
CEP90_RS26500 18340..18609 + 270 WP_000079941.1 hypothetical protein Antitoxin
CEP90_RS26505 18606..18887 + 282 WP_000970007.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
CEP90_RS26510 18927..19775 + 849 WP_001057992.1 3'-5' exonuclease -
CEP90_RS26515 19892..20365 + 474 WP_001334658.1 hypothetical protein -
CEP90_RS26525 20842..21108 - 267 WP_000955263.1 hypothetical protein -
CEP90_RS26530 21108..21602 - 495 WP_001459505.1 hypothetical protein -
CEP90_RS26535 21658..22260 - 603 WP_000517695.1 hypothetical protein -
CEP90_RS26545 22614..23498 + 885 Protein_26 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..109170 109170


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 94 a.a.        Molecular weight: 12066.38 Da        Isoelectric Point: 12.7685

>T78338 WP_000970007.1 NZ_CP022064:18606-18887 [Salmonella enterica subsp. enterica serovar Typhimurium var. 5-]
KKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKK
KKKKKKKKKKKKKK

Download         Length: 282 bp

>T78338 NZ_CP022064:18606-18887 [Salmonella enterica subsp. enterica serovar Typhimurium var. 5-]
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA

Antitoxin


Download         Length: 90 a.a.        Molecular weight: 11553.68 Da        Isoelectric Point: 12.7493

>AT78338 WP_000079941.1 NZ_CP022064:18340-18609 [Salmonella enterica subsp. enterica serovar Typhimurium var. 5-]
KKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKK
KKKKKKKKKK

Download         Length: 270 bp

>AT78338 NZ_CP022064:18340-18609 [Salmonella enterica subsp. enterica serovar Typhimurium var. 5-]
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A7G1GDN5

Antitoxin

Source ID Structure
AlphaFold DB A0A629TXC5

References