Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 29815..30086 Replicon chromosome
Accession NZ_CP022050
Organism Escherichia coli O157 strain FDAARGOS_293

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 29853..29956 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 29815..30086 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CEP72_RS00160 26972..28411 + 1440 WP_001302304.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
CEP72_RS00165 28529..28765 + 237 WP_001295499.1 DUF1480 family protein -
CEP72_RS00170 28870..29061 + 192 WP_001296140.1 YebW family protein -
CEP72_RS00175 29062..29718 - 657 WP_000812736.1 protein-serine/threonine phosphatase -
- 29815..30086 + 272 - - Antitoxin
- 29853..29956 - 104 - - Toxin
CEP72_RS00180 30114..30455 - 342 WP_000976483.1 YebY family protein -
CEP72_RS00185 30468..31340 - 873 WP_000879314.1 copper homeostasis membrane protein CopD -
CEP72_RS00190 31344..31718 - 375 WP_000168751.1 CopC domain-containing protein YobA -
CEP72_RS00195 31857..32087 + 231 WP_000916763.1 DNA polymerase III subunit theta -
CEP72_RS00200 32189..32845 + 657 WP_000011656.1 carbon-nitrogen hydrolase family protein -
CEP72_RS00205 32869..33531 + 663 WP_000944243.1 exodeoxyribonuclease X -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T78254 NZ_CP022050:c29956-29853 [Escherichia coli O157]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT78254 NZ_CP022050:29815-30086 [Escherichia coli O157]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References