Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) tsbAT/-
Location 779014..779764 Replicon chromosome
Accession NZ_CP022046
Organism Mammaliicoccus sciuri strain FDAARGOS_285

Toxin (Protein)


Gene name tsbT Uniprot ID -
Locus tag CEP64_RS18075 Protein ID WP_101494413.1
Coordinates 779657..779764 (+) Length 36 a.a.

Antitoxin (Protein)


Gene name tsbA Uniprot ID -
Locus tag CEP64_RS18070 Protein ID WP_048539838.1
Coordinates 779014..779613 (+) Length 200 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CEP64_RS18050 774617..775378 + 762 WP_048539835.1 acetylglutamate kinase -
CEP64_RS18055 775948..777075 + 1128 WP_078355955.1 tRNA epoxyqueuosine(34) reductase QueG -
CEP64_RS18060 777079..777552 + 474 WP_025904798.1 tRNA (uridine(34)/cytosine(34)/5- carboxymethylaminomethyluridine(34)-2'-O)- methyltransferase TrmL -
CEP64_RS28240 777587..777727 - 141 WP_162841915.1 hypothetical protein -
CEP64_RS18065 777814..778965 + 1152 WP_078355954.1 N-acetylglucosamine-6-phosphate deacetylase -
CEP64_RS18070 779014..779613 + 600 WP_048539838.1 glucosamine-6-phosphate isomerase Antitoxin
CEP64_RS18075 779657..779764 + 108 WP_101494413.1 hypothetical protein Toxin
CEP64_RS18080 779917..781305 + 1389 WP_048539839.1 class II fumarate hydratase -
CEP64_RS18085 781395..782921 + 1527 WP_058591068.1 exopolyphosphatase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Glucosamine-6-phosphate isomerase

(134-195)


Sequences

Toxin        


Download         Length: 36 a.a.        Molecular weight: 4130.43 Da        Isoelectric Point: 3.7615

>T78234 WP_101494413.1 NZ_CP022046:779657-779764 [Mammaliicoccus sciuri]
MVQDLEDVKELGKEMEQISEQNDEAFEEKKSEQES

Download         Length: 108 bp

>T78234 NZ_CP022046:779657-779764 [Mammaliicoccus sciuri]
ATGGTTCAAGACCTAGAAGATGTTAAAGAACTAGGTAAAGAAATGGAACAAATATCAGAACAAAATGATGAAGCTTTTGA
AGAAAAGAAATCTGAACAAGAGTCTTAA

Antitoxin


Download         Length: 200 a.a.        Molecular weight: 22290.17 Da        Isoelectric Point: 4.9758

>AT78234 WP_048539838.1 NZ_CP022046:779014-779613 [Mammaliicoccus sciuri]
MALNFKVFETKDIAARYAADVVRKQFNSDSTSVVGVHLEAEQTSFFDELLDDVKKNPVNFSQIHILDFDGKEDYYTELGV
PAKQVLKTDVGSDVEAFIKEKVNTDKKKNKLMLDVVTLTEDSRTGLDYNQAIHPAREVIVLVTGKEKAKAVSQLYQEPAN
GSVESAKLKQHRMVTVVLDNEAAQGLPEDVRSYFSIQFS

Download         Length: 600 bp

>AT78234 NZ_CP022046:779014-779613 [Mammaliicoccus sciuri]
ATGGCTTTAAACTTTAAAGTATTTGAAACAAAAGATATTGCTGCACGATATGCTGCAGATGTAGTTCGCAAACAATTTAA
TTCAGACAGCACTTCAGTTGTCGGTGTACATTTAGAAGCTGAGCAAACATCATTTTTCGATGAACTATTAGATGATGTTA
AGAAAAATCCTGTGAACTTCAGTCAAATTCATATTTTAGATTTTGACGGTAAAGAAGATTATTACACAGAATTAGGTGTC
CCAGCTAAACAAGTATTAAAAACTGATGTCGGTAGTGATGTTGAAGCATTTATTAAAGAAAAAGTGAATACTGACAAAAA
GAAAAACAAATTGATGTTAGATGTTGTCACTTTAACTGAAGATAGTAGAACTGGATTAGACTATAATCAAGCAATTCACC
CAGCAAGAGAAGTTATCGTACTTGTCACTGGTAAAGAAAAAGCTAAAGCAGTAAGTCAGTTATATCAAGAACCTGCAAAT
GGTTCTGTTGAATCCGCTAAATTAAAACAACATAGAATGGTAACAGTTGTATTAGATAATGAAGCGGCACAAGGCTTACC
TGAAGACGTTAGATCTTACTTCTCAATTCAATTTTCATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References