Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 5180825..5180970 Replicon chromosome
Accession NZ_CP022023
Organism Klebsiella pneumoniae strain 19051

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 5180832..5180934 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 5180825..5180970 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CDA51_RS25800 5176356..5177789 + 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
CDA51_RS25805 5177905..5178144 + 240 WP_002911393.1 YebV family protein -
CDA51_RS25810 5178242..5178433 + 192 WP_002911395.1 YebW family protein -
CDA51_RS25815 5178430..5179083 - 654 WP_004180432.1 protein-serine/threonine phosphatase -
CDA51_RS25820 5179240..5180208 + 969 WP_004151446.1 VirK/YbjX family protein -
CDA51_RS26855 5180313..5180456 + 144 WP_002911398.1 Ecr family regulatory small membrane protein -
- 5180825..5180970 + 146 - - Antitoxin
- 5180832..5180934 - 103 - - Toxin
CDA51_RS25830 5181093..5181431 - 339 WP_002911404.1 YebY family protein -
CDA51_RS25835 5181448..5182317 - 870 WP_004151447.1 copper homeostasis membrane protein CopD -
CDA51_RS25840 5182321..5182695 - 375 WP_004151448.1 CopC domain-containing protein YobA -
CDA51_RS25845 5182808..5183038 + 231 WP_002911406.1 DNA polymerase III subunit theta -
CDA51_RS25850 5183117..5183776 + 660 WP_020324964.1 exodeoxyribonuclease X -
CDA51_RS25855 5183780..5185840 - 2061 WP_004151449.1 oligopeptidase B -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T78213 NZ_CP022023:c5180934-5180832 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT78213 NZ_CP022023:5180825-5180970 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References