Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) tacT-ataR/DUF1778(antitoxin)
Location 392896..393628 Replicon chromosome
Accession NZ_CP022010
Organism Mergibacter septicus strain 27643-20-I1

Toxin (Protein)


Gene name tacT Uniprot ID -
Locus tag CEP45_RS01860 Protein ID WP_261919529.1
Coordinates 392896..393363 (-) Length 156 a.a.

Antitoxin (Protein)


Gene name ataR Uniprot ID -
Locus tag CEP45_RS01865 Protein ID WP_261919528.1
Coordinates 393365..393628 (-) Length 88 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CEP45_RS01845 (CEP45_01825) 389308..390381 + 1074 WP_265491235.1 alanine racemase -
CEP45_RS01850 (CEP45_01830) 390398..392047 + 1650 WP_265490911.1 glucose-6-phosphate isomerase -
CEP45_RS01855 (CEP45_01835) 392120..392647 - 528 WP_265490912.1 peptide-methionine (S)-S-oxide reductase MsrA -
CEP45_RS01860 (CEP45_01840) 392896..393363 - 468 WP_261919529.1 GNAT family N-acetyltransferase Toxin
CEP45_RS01865 (CEP45_01845) 393365..393628 - 264 WP_261919528.1 DUF1778 domain-containing protein Antitoxin
CEP45_RS01870 (CEP45_01850) 393847..396705 - 2859 WP_265490913.1 valine--tRNA ligase -
CEP45_RS01875 (CEP45_01855) 396742..397188 - 447 WP_265490914.1 DNA polymerase III subunit chi -
CEP45_RS01880 (CEP45_01860) 397326..397937 - 612 WP_261919525.1 recombination mediator RecR -
CEP45_RS01885 (CEP45_01865) 397981..398310 - 330 WP_265490915.1 YbaB/EbfC family nucleoid-associated protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

GNAT domain

(41-143)

Antitoxin

Vibrio phage ICP1, Orf50

(3-86)


Sequences

Toxin        


Download         Length: 156 a.a.        Molecular weight: 17426.33 Da        Isoelectric Point: 10.1606

>T78100 WP_261919529.1 NZ_CP022010:c393363-392896 [Mergibacter septicus]
MYSAPELLTHNHRLDFFDCGEESLNIWLRRNALKNQQNQASRTFVICKENIVVGFYALAAGAVTHQFASSTLRRNMPEPI
PVVVLGRLAIDVKHQGKKLGAALLKDVVLRSKSISEQIGVRALLVHALNNKAKQFYLHYGFQPSPIDDMSLMLKL

Download         Length: 468 bp

>T78100 NZ_CP022010:c393363-392896 [Mergibacter septicus]
ATGTATTCAGCACCTGAATTACTAACGCATAATCATCGCCTAGATTTCTTTGATTGCGGAGAAGAATCATTAAATATATG
GCTTAGACGAAATGCACTTAAAAATCAACAAAACCAAGCAAGTAGAACATTTGTGATCTGTAAGGAAAATATTGTTGTTG
GTTTTTATGCTTTAGCAGCAGGGGCGGTTACTCATCAATTTGCATCAAGTACATTAAGACGTAATATGCCAGAACCTATC
CCTGTCGTTGTTTTAGGGCGATTAGCCATAGATGTAAAACATCAAGGAAAAAAATTAGGTGCTGCACTACTCAAAGATGT
TGTGTTAAGATCGAAATCCATATCAGAACAAATTGGAGTAAGGGCATTGCTAGTTCATGCTTTGAATAATAAAGCAAAGC
AATTCTATTTACATTATGGTTTTCAACCATCTCCAATTGATGATATGTCACTAATGTTGAAGTTGTAA

Antitoxin


Download         Length: 88 a.a.        Molecular weight: 9916.59 Da        Isoelectric Point: 6.2649

>AT78100 WP_261919528.1 NZ_CP022010:c393628-393365 [Mergibacter septicus]
MRTAAINLRAKPMQRDLIDQAAALLGKTRSDFMLDAACTYAQNVILERTVFQLSEEKFNCFIEVLEQPNIANTKLEKLMA
IKSPWEV

Download         Length: 264 bp

>AT78100 NZ_CP022010:c393628-393365 [Mergibacter septicus]
ATGCGTACCGCTGCAATTAATTTACGAGCCAAACCAATGCAACGTGATTTGATTGATCAAGCTGCTGCATTATTAGGCAA
AACACGTTCTGATTTTATGCTAGATGCGGCTTGTACCTATGCACAAAACGTCATTTTAGAGAGAACAGTATTTCAATTAA
GTGAAGAGAAATTTAACTGTTTTATTGAGGTACTAGAACAACCTAACATCGCTAATACTAAATTAGAAAAATTAATGGCT
ATTAAATCCCCTTGGGAAGTATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References