78098

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/upstrm_HI1419-dnstrm_HI1420
Location 2147211..2147786 Replicon chromosome
Accession NZ_CP022006
Organism Burkholderia gladioli pv. gladioli strain KACC 11889

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag CEJ98_RS29400 Protein ID WP_036054553.1
Coordinates 2147211..2147498 (+) Length 96 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A560UNM0
Locus tag CEJ98_RS29405 Protein ID WP_036030606.1
Coordinates 2147502..2147786 (+) Length 95 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CEJ98_RS29380 2143327..2144388 - 1062 WP_013689307.1 selenide, water dikinase SelD -
CEJ98_RS29385 2144633..2145469 + 837 WP_036054549.1 DMT family transporter -
CEJ98_RS29390 2145513..2145983 - 471 WP_013689305.1 Lrp/AsnC family transcriptional regulator -
CEJ98_RS29395 2146140..2147078 + 939 WP_036054551.1 2-dehydropantoate 2-reductase -
CEJ98_RS29400 2147211..2147498 + 288 WP_036054553.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
CEJ98_RS29405 2147502..2147786 + 285 WP_036030606.1 putative addiction module antidote protein Antitoxin
CEJ98_RS29410 2147844..2148170 - 327 WP_036054555.1 hypothetical protein -
CEJ98_RS29415 2148319..2149446 - 1128 WP_167547494.1 ABC transporter substrate-binding protein -
CEJ98_RS29420 2149632..2151269 - 1638 WP_036054559.1 PLP-dependent aminotransferase family protein -
CEJ98_RS29425 2151405..2152688 + 1284 WP_013689299.1 4-aminobutyrate--2-oxoglutarate transaminase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Addiction module killer protein, predicted

(5-94)

Antitoxin

Uncharacterized protein HI1420

(11-89)


Sequences

Toxin        


Download         Length: 96 a.a.        Molecular weight: 10959.72 Da        Isoelectric Point: 10.4966

>T78098 WP_036054553.1 NZ_CP022006:2147211-2147498 [Burkholderia gladioli pv. gladioli]
MLRSSEFTNWLSSLRDQRGKARIAARLISAQLGNFGEYRVIGEGVREMKVDFGPGYRIYYVRRAEIVYVLLCGGDKSTQK
KDIKRALQMARELKE

Download         Length: 288 bp

>T78098 NZ_CP022006:2147211-2147498 [Burkholderia gladioli pv. gladioli]
TTGCTGCGCTCCAGTGAATTCACAAACTGGCTTTCCAGCCTGCGTGATCAGCGCGGCAAAGCCCGAATCGCCGCACGCCT
GATCAGTGCCCAGCTAGGCAATTTTGGCGAGTACCGCGTGATAGGCGAAGGCGTCCGCGAAATGAAGGTCGACTTCGGGC
CGGGTTATCGCATCTACTATGTCCGTCGCGCCGAGATCGTCTATGTCCTTCTCTGCGGTGGCGATAAATCTACACAGAAA
AAAGACATCAAGCGCGCGCTCCAGATGGCGCGCGAACTGAAGGAGTAA

Antitoxin


Download         Length: 95 a.a.        Molecular weight: 10072.47 Da        Isoelectric Point: 5.0484

>AT78098 WP_036030606.1 NZ_CP022006:2147502-2147786 [Burkholderia gladioli pv. gladioli]
MPDYAEFDAADYLDNDETVAEFLAVAAEDPDPAVFLAAVAAVARARGMTKVASEAGLGRVTLHKALTPGAHPRYETVQKI
LRSLGLRMTFTVAH

Download         Length: 285 bp

>AT78098 NZ_CP022006:2147502-2147786 [Burkholderia gladioli pv. gladioli]
ATGCCCGATTACGCCGAATTCGATGCGGCCGACTATCTCGACAATGACGAAACCGTGGCGGAATTTCTCGCGGTTGCGGC
AGAGGATCCCGATCCCGCAGTGTTCCTTGCTGCCGTGGCCGCTGTCGCACGCGCGCGCGGGATGACCAAGGTGGCGTCGG
AAGCCGGCCTTGGACGGGTCACCTTGCACAAGGCGCTGACGCCTGGCGCTCACCCTCGATATGAGACCGTGCAGAAGATC
CTGCGCTCGCTGGGCCTTCGCATGACCTTCACCGTCGCCCACTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A560UNM0

References