78095

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-StbC
Location 115874..116516 Replicon chromosome
Accession NZ_CP022006
Organism Burkholderia gladioli pv. gladioli strain KACC 11889

Toxin (Protein)


Gene name vapC Uniprot ID A0A808W1S4
Locus tag CEJ98_RS21580 Protein ID WP_036055816.1
Coordinates 116094..116516 (+) Length 141 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID A0A808W4F3
Locus tag CEJ98_RS21575 Protein ID WP_036033948.1
Coordinates 115874..116107 (+) Length 78 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CEJ98_RS21560 111842..112090 - 249 WP_013690725.1 acyl carrier protein -
CEJ98_RS21565 112215..113981 - 1767 WP_036055814.1 AMP-binding protein -
CEJ98_RS21570 114569..115558 + 990 WP_036055815.1 LysR family transcriptional regulator -
CEJ98_RS21575 115874..116107 + 234 WP_036033948.1 DNA-binding protein Antitoxin
CEJ98_RS21580 116094..116516 + 423 WP_036055816.1 type II toxin-antitoxin system VapC family toxin Toxin
CEJ98_RS21585 116638..117318 - 681 WP_036055817.1 deoxyribose-phosphate aldolase -
CEJ98_RS21590 117468..118238 + 771 WP_036055818.1 DNA-binding transcriptional repressor DeoR -
CEJ98_RS21595 118258..119340 - 1083 WP_036055819.1 aldose 1-epimerase family protein -
CEJ98_RS21600 119343..120716 - 1374 WP_036055820.1 L-fucose:H+ symporter permease -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(2-124)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 141 a.a.        Molecular weight: 15659.95 Da        Isoelectric Point: 8.5438

>T78095 WP_036055816.1 NZ_CP022006:116094-116516 [Burkholderia gladioli pv. gladioli]
MYLIDTNVVSEVRKRDRADKGVMAFFRQAARDDAGLYLSVVTVGELRRGVEIIRHRGDESQATRLANWLDGVLREFAANI
LVVDKEIGQMWGYLRVPRPEHSLDKVIAATALIHDLTVVTRNVDDFAGTGARVLNPFKGP

Download         Length: 423 bp

>T78095 NZ_CP022006:116094-116516 [Burkholderia gladioli pv. gladioli]
ATGTATTTGATTGACACCAATGTGGTCAGCGAAGTCCGGAAACGGGATCGTGCGGACAAGGGTGTGATGGCCTTCTTTCG
CCAGGCGGCCCGCGACGATGCCGGCCTGTACCTGTCGGTGGTGACGGTGGGCGAACTGCGGCGAGGTGTGGAAATCATCC
GTCACCGTGGCGACGAATCCCAGGCAACGCGTCTCGCGAACTGGCTCGATGGCGTGCTCCGGGAGTTTGCCGCGAACATT
CTCGTGGTGGACAAGGAGATCGGGCAGATGTGGGGCTACCTGCGTGTACCTCGCCCGGAACACTCGCTGGATAAGGTGAT
CGCCGCCACGGCCTTGATTCACGATCTGACCGTGGTGACGCGCAACGTGGATGATTTCGCCGGAACCGGTGCCCGTGTGC
TGAACCCGTTCAAGGGCCCATAG

Antitoxin


Download         Length: 78 a.a.        Molecular weight: 8484.61 Da        Isoelectric Point: 5.5741

>AT78095 WP_036033948.1 NZ_CP022006:115874-116107 [Burkholderia gladioli pv. gladioli]
MANLLVRNVDEMLVQILRERAAAHGHSAEAEHRAILARALREPQRKTFAQVLMGMPNVGSDADFARVDDGEAANVFD

Download         Length: 234 bp

>AT78095 NZ_CP022006:115874-116107 [Burkholderia gladioli pv. gladioli]
ATGGCGAATCTTCTGGTGAGAAACGTGGACGAAATGCTTGTTCAAATCTTGCGCGAGCGGGCTGCCGCTCACGGGCACAG
CGCGGAAGCCGAGCATCGTGCAATCCTGGCAAGGGCGCTGCGCGAGCCGCAACGCAAGACATTCGCGCAAGTGCTGATGG
GCATGCCGAACGTCGGTAGCGATGCCGATTTTGCGCGCGTGGACGATGGCGAGGCGGCGAATGTATTTGATTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A808W1S4

Antitoxin

Source ID Structure
AlphaFold DB A0A808W4F3

References