78094

Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) vapBC/-
Location 3511542..3512780 Replicon chromosome
Accession NZ_CP022005
Organism Burkholderia gladioli pv. gladioli strain KACC 11889

Toxin (Protein)


Gene name vapC Uniprot ID A0A808W951
Locus tag CEJ98_RS15650 Protein ID WP_036049937.1
Coordinates 3511542..3512126 (-) Length 195 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag CEJ98_RS15655 Protein ID WP_196788438.1
Coordinates 3512229..3512780 (-) Length 184 a.a.

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CEJ98_RS15625 3507316..3507732 + 417 WP_036053101.1 DUF302 domain-containing protein -
CEJ98_RS15630 3507857..3508819 - 963 WP_036040951.1 AraC family transcriptional regulator -
CEJ98_RS39630 3509014..3509832 - 819 WP_052710575.1 lytic transglycosylase domain-containing protein -
CEJ98_RS15640 3510237..3510983 - 747 WP_052409298.1 hypothetical protein -
CEJ98_RS15650 3511542..3512126 - 585 WP_036049937.1 HD domain-containing protein Toxin
CEJ98_RS15655 3512229..3512780 - 552 WP_196788438.1 helix-turn-helix domain-containing protein Antitoxin
CEJ98_RS15660 3512976..3513239 - 264 WP_013698802.1 PAAR domain-containing protein -
CEJ98_RS15665 3513306..3513729 - 424 Protein_3098 hypothetical protein -
CEJ98_RS15670 3513773..3515788 - 2016 WP_036049934.1 VC_2705 family sodium/solute symporter -
CEJ98_RS15675 3515782..3516219 - 438 WP_080742279.1 DUF4212 domain-containing protein -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin

(8-187)

Antitoxin

(11-61)


Sequences


Toxin        


Download         Length: 195 a.a.        Molecular weight: 21529.30 Da        Isoelectric Point: 5.0096

>T78094 WP_036049937.1 NZ_CP022005:c3512126-3511542 [Burkholderia gladioli pv. gladioli]
MDDALIDARLDFLRGCERLKDVLRSGHTSGGRRESTAEHSWRLALMAMVLMDQLGEVDPGRVLELCLVHDLGEALGGDVP
APEQAPGSDKDAAERRDLLRLGDALDAPMRERIVALWDEYARAATPEARAVKALDKIETILQHTQGENPPDFDYAFNLAY
GQAHTRKVPALQRFRERVDEATRERMARAGGPSC

Download         Length: 585 bp

>T78094 NZ_CP022005:c3512126-3511542 [Burkholderia gladioli pv. gladioli]
ATGGACGACGCGTTGATCGACGCACGACTGGATTTCCTGCGCGGCTGCGAGCGCCTGAAGGATGTGCTGCGCAGCGGCCA
TACCTCGGGCGGGCGACGCGAGAGCACGGCCGAGCACAGCTGGCGGCTCGCGCTGATGGCGATGGTGCTGATGGATCAAT
TGGGCGAGGTCGACCCCGGCAGGGTGCTCGAGCTCTGCCTGGTGCATGACCTGGGCGAAGCGCTGGGCGGCGACGTGCCG
GCGCCCGAGCAGGCCCCGGGCAGCGACAAGGATGCCGCCGAGCGACGCGACCTGCTGCGCCTCGGCGACGCGCTCGATGC
GCCGATGCGCGAGAGGATCGTCGCGTTGTGGGACGAGTATGCGCGGGCGGCCACGCCGGAAGCACGCGCGGTGAAGGCGC
TCGACAAGATCGAGACGATCCTGCAGCACACGCAGGGCGAGAATCCGCCCGATTTCGACTATGCGTTCAACCTCGCGTAT
GGACAGGCGCATACCCGCAAGGTGCCGGCGCTGCAGCGGTTTCGCGAGCGCGTCGACGAGGCGACGCGCGAGCGGATGGC
CCGTGCTGGCGGGCCTTCGTGCTGA

Antitoxin


Download         Length: 184 a.a.        Molecular weight: 20143.87 Da        Isoelectric Point: 8.3940

>AT78094 WP_196788438.1 NZ_CP022005:c3512780-3512229 [Burkholderia gladioli pv. gladioli]
MPPSALACSPGASLRRWRTLRRIKQEHAAALFGVSQSTISRWEAGTQAVSHEELRRIEACLSARLDSAADRALERLVSHH
TRPVHLVCDLTHRLLACSAPRAAEFAAPLSSLMGASLWPFATAEIVAREQSLRDAGWQDHPAPSIEFDTGSNDSPQVPIR
ASRCRWTRFTLSDGTLARLVETL

Download         Length: 552 bp

>AT78094 NZ_CP022005:c3512780-3512229 [Burkholderia gladioli pv. gladioli]
TTGCCGCCGTCCGCGCTGGCCTGTTCGCCGGGCGCGAGCTTGCGTCGATGGCGCACGCTGCGCCGGATCAAGCAGGAACA
TGCAGCGGCGCTGTTCGGCGTATCGCAGTCGACGATATCGCGCTGGGAAGCCGGCACGCAGGCGGTGTCGCACGAGGAAC
TGCGGCGCATCGAGGCCTGCTTGTCGGCGCGCCTCGACTCGGCGGCGGATCGCGCGCTCGAGCGCCTCGTCAGCCATCAC
ACCCGTCCCGTTCATCTCGTCTGCGACCTCACGCACCGGCTGCTGGCCTGCTCCGCGCCGCGAGCCGCGGAGTTCGCGGC
GCCGCTGTCGTCGCTGATGGGCGCGTCGCTCTGGCCGTTCGCGACGGCCGAGATCGTGGCGCGCGAGCAGTCGTTGCGCG
ATGCGGGCTGGCAAGATCATCCGGCACCCTCGATCGAATTCGATACCGGGTCCAACGATTCGCCTCAGGTGCCGATTCGT
GCGAGCCGCTGCCGCTGGACGCGTTTCACCTTGTCCGACGGGACGCTGGCGCGCCTGGTCGAGACGCTTTGA

Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure
AlphaFold DB A0A808W951


Antitoxin

Source ID Structure

References