Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) /BrnT(toxin)
Location 4003988..4004468 Replicon chromosome
Accession NZ_CP021983
Organism Halomicronema hongdechloris C2206

Toxin (Protein)


Gene name - Uniprot ID -
Locus tag XM38_RS18135 Protein ID WP_088430608.1
Coordinates 4003988..4004251 (+) Length 88 a.a.

Antitoxin (Protein)


Gene name - Uniprot ID -
Locus tag XM38_RS18140 Protein ID WP_080806923.1
Coordinates 4004241..4004468 (+) Length 76 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
XM38_RS18120 3999503..4002787 - 3285 WP_088430606.1 carbamoyl-phosphate synthase large subunit -
XM38_RS18125 4003456..4003662 - 207 WP_137455165.1 hypothetical protein -
XM38_RS18130 4003782..4003985 + 204 WP_080806919.1 DUF433 domain-containing protein -
XM38_RS18135 4003988..4004251 + 264 WP_088430608.1 BrnT family toxin Toxin
XM38_RS18140 4004241..4004468 + 228 WP_080806923.1 CopG family transcriptional regulator Antitoxin
XM38_RS18145 4004491..4004724 + 234 WP_088430610.1 hypothetical protein -
XM38_RS18150 4004840..4005402 + 563 Protein_3619 DEAD/DEAH box helicase family protein -
XM38_RS18160 4005848..4006234 + 387 WP_080806927.1 DUF4359 domain-containing protein -
XM38_RS18165 4006476..4007366 + 891 WP_137455166.1 sirohydrochlorin chelatase -
XM38_RS18170 4007402..4008184 + 783 WP_202979056.1 uroporphyrinogen-III C-methyltransferase -
XM38_RS18175 4008280..4008843 + 564 WP_080806929.1 peptide deformylase -
XM38_RS18180 4008916..4009113 + 198 WP_080806931.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Ribonuclease toxin, BrnT, of type II toxin-antitoxin system

(6-81)

Antitoxin

CopG antitoxin

(4-68)


Sequences

Toxin        


Download         Length: 88 a.a.        Molecular weight: 10104.39 Da        Isoelectric Point: 7.2020

>T78059 WP_088430608.1 NZ_CP021983:4003988-4004251 [Halomicronema hongdechloris C2206]
MPTFEYDENKSQSNLAKHGIDFVEAQKLWDAPNTFVIPAKTEDETRFLIIGKIGDKHWTAVITYRGQNTRIISVRRSRKE
EVAFYEG

Download         Length: 264 bp

>T78059 NZ_CP021983:4003988-4004251 [Halomicronema hongdechloris C2206]
ATGCCTACGTTTGAGTACGATGAAAACAAAAGCCAGTCAAACTTGGCGAAGCATGGCATCGACTTTGTGGAAGCCCAAAA
ACTGTGGGATGCCCCCAACACCTTTGTGATTCCTGCTAAAACCGAAGACGAAACCCGATTTTTGATCATCGGTAAGATAG
GGGATAAGCATTGGACAGCAGTGATCACCTACCGAGGGCAGAATACGCGCATTATTTCCGTTCGGCGATCGCGCAAAGAA
GAGGTGGCATTCTATGAAGGCTAA

Antitoxin


Download         Length: 76 a.a.        Molecular weight: 8430.32 Da        Isoelectric Point: 4.0808

>AT78059 WP_080806923.1 NZ_CP021983:4004241-4004468 [Halomicronema hongdechloris C2206]
MKAKDFDQQFEDGEDLTPYLDLSQAKRLGSDRQSISIDLPVWLLERINEEANRLGTTAQDVIQTSLAEHLAASEP

Download         Length: 228 bp

>AT78059 NZ_CP021983:4004241-4004468 [Halomicronema hongdechloris C2206]
ATGAAGGCTAAAGACTTCGACCAACAATTTGAGGATGGAGAAGACCTCACCCCCTACCTTGACCTCTCCCAGGCGAAGCG
ATTGGGGAGCGATCGGCAAAGCATCAGTATCGATCTTCCTGTCTGGCTGCTAGAGCGCATTAACGAAGAAGCCAACCGCT
TAGGCACCACCGCTCAAGATGTGATTCAAACGTCTCTGGCAGAGCATCTTGCCGCCAGCGAGCCCTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References