Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PumA-relB/upstrm_HI1419-dnstrm_HI1420
Location 3743804..3744278 Replicon chromosome
Accession NZ_CP021983
Organism Halomicronema hongdechloris C2206

Toxin (Protein)


Gene name PumA Uniprot ID -
Locus tag XM38_RS16995 Protein ID WP_080806606.1
Coordinates 3744117..3744278 (-) Length 54 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag XM38_RS16990 Protein ID WP_080806608.1
Coordinates 3743804..3744106 (-) Length 101 a.a.

Genomic Context

XM38_RS16955XM38_RS16960XM38_RS16965XM38_RS17020XM38_RS17025XM38_RS17030XM38_RS16950XM38_RS26070XM38_RS16975XM38_RS16980XM38_RS16985XM38_RS16990XM38_RS16995XM38_RS17000XM38_RS17005XM38_RS17010
Location: 3740414..3741064 (651 bp)
Type: Others
Protein ID: WP_202979051.1
Location: 3741133..3741573 (441 bp)
Type: Others
Protein ID: WP_088430496.1
Location: 3741608..3741998 (391 bp)
Type: Others
Protein ID: Protein_3385
Location: 3746694..3747809 (1116 bp)
Type: Others
Protein ID: WP_088430498.1
Location: 3747939..3748151 (213 bp)
Type: Others
Protein ID: WP_080806597.1
Location: 3748747..3748995 (249 bp)
Type: Others
Protein ID: WP_137455151.1
Location: 3738831..3740291 (1461 bp)
Type: Others
Protein ID: WP_088430494.1
Location: 3741936..3742301 (366 bp)
Type: Others
Protein ID: WP_187329584.1
Location: 3742298..3742678 (381 bp)
Type: Others
Protein ID: WP_080806612.1
Location: 3742675..3743043 (369 bp)
Type: Others
Protein ID: WP_080806611.1
Location: 3743072..3743680 (609 bp)
Type: Others
Protein ID: WP_080806610.1
Location: 3743804..3744106 (303 bp)
Type: Antitoxin
Protein ID: WP_080806608.1
Location: 3744117..3744278 (162 bp)
Type: Toxin
Protein ID: WP_080806606.1
Location: 3744493..3744978 (486 bp)
Type: Others
Protein ID: WP_080806604.1
Location: 3745696..3745941 (246 bp)
Type: Others
Protein ID: WP_080806600.1
Location: 3745925..3746200 (276 bp)
Type: Others
Protein ID: WP_080806598.1
ToxinAntitoxinOther genes
Loading, please wait
Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
XM38_RS169503738831..3740291-1461WP_088430494.1PLP-dependent aminotransferase family protein-
XM38_RS169553740414..3741064+651WP_202979051.1pyridoxamine 5'-phosphate oxidase family protein-
XM38_RS169603741133..3741573+441WP_088430496.1gamma-glutamylcyclotransferase-
XM38_RS169653741608..3741998+391Protein_3385RidA family protein-
XM38_RS260703741936..3742301-366WP_187329584.1hypothetical protein-
XM38_RS169753742298..3742678-381WP_080806612.1HEPN domain-containing protein-
XM38_RS169803742675..3743043-369WP_080806611.1nucleotidyltransferase domain-containing protein-
XM38_RS169853743072..3743680-609WP_080806610.1Uma2 family endonuclease-
XM38_RS169903743804..3744106-303WP_080806608.1putative addiction module antidote proteinAntitoxin
XM38_RS169953744117..3744278-162WP_080806606.1addiction module killer proteinToxin
XM38_RS170003744493..3744978-486WP_080806604.1hypothetical protein-
XM38_RS170053745696..3745941-246WP_080806600.1hypothetical protein-
XM38_RS170103745925..3746200-276WP_080806598.1BrnT family toxin-
XM38_RS170203746694..3747809+1116WP_088430498.1IS66 family transposase-
XM38_RS170253747939..3748151+213WP_080806597.1hypothetical protein-
XM38_RS170303748747..3748995+249WP_137455151.1hypothetical protein-

Associated MGEs

Loading, please wait
MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
-flankIS/Tn--3746694..37478091115


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Addiction module killer protein, predicted

(1-52)

Antitoxin

Uncharacterized protein HI1420

(7-92)


Sequences

Toxin        


Download         Length: 54 a.a.        Molecular weight: 5991.93 Da        Isoelectric Point: 9.5923

>T78058 WP_080806606.1 NZ_CP021983:c3744278-3744117 [Halomicronema hongdechloris C2206]
VGQGVSELRINYGPEYRVYFIQRGETLVILLAEGDNKTQKRDIKAALELAKKV

Download         Length: 162 bp

>T78058 NZ_CP021983:c3744278-3744117 [Halomicronema hongdechloris C2206]
GTGGGTCAAGGCGTCTCAGAACTACGGATTAACTATGGCCCAGAGTATCGGGTGTATTTCATCCAACGTGGCGAGACCTT
AGTCATCCTTTTAGCAGAAGGCGATAACAAGACTCAAAAACGCGATATTAAAGCAGCCTTGGAACTAGCGAAAAAGGTAT
AG

Antitoxin


Download         Length: 101 a.a.        Molecular weight: 10828.31 Da        Isoelectric Point: 4.4354

>AT78058 WP_080806608.1 NZ_CP021983:c3744106-3743804 [Halomicronema hongdechloris C2206]
MTKLQTYPWDASDHLETQEDIIAYLQAALEEDDPSLVTAALGDIARSKGMTQLAQATGLGRESLYKALSREGNPEFATVL
KVLRALGLRLQVVAVAVQEG

Download         Length: 303 bp

>AT78058 NZ_CP021983:c3744106-3743804 [Halomicronema hongdechloris C2206]
ATGACCAAACTACAAACCTATCCTTGGGATGCGTCCGACCATCTAGAAACCCAGGAAGATATCATTGCCTATTTGCAAGC
AGCGCTAGAAGAAGACGATCCCAGCCTTGTGACAGCGGCGTTAGGCGATATTGCGCGTTCTAAAGGCATGACCCAGCTCG
CCCAGGCAACCGGATTAGGGCGTGAAAGTCTTTATAAAGCCCTATCGAGGGAAGGTAACCCAGAGTTTGCCACTGTGCTT
AAGGTTTTGCGAGCCTTAGGCTTACGTTTGCAAGTTGTCGCGGTTGCTGTTCAAGAGGGCTAA

Similar Proteins

Only experimentally validated proteins are listed.

Loading, please wait
Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
Loading, please wait
Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

Loading, please wait
Source
ID
Structure
No matching records found

Antitoxin

Loading, please wait
Source
ID
Structure
No matching records found

References