Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) mazEF/PRK09907-MazE
Location 1088031..1088614 Replicon chromosome
Accession NZ_CP021983
Organism Halomicronema hongdechloris C2206

Toxin (Protein)


Gene name mazF Uniprot ID -
Locus tag XM38_RS05030 Protein ID WP_080806330.1
Coordinates 1088031..1088378 (-) Length 116 a.a.

Antitoxin (Protein)


Gene name mazE Uniprot ID -
Locus tag XM38_RS05035 Protein ID WP_080806331.1
Coordinates 1088372..1088614 (-) Length 81 a.a.

Genomic Context


XM38_RS05015XM38_RS05020XM38_RS04995XM38_RS05000XM38_RS05005XM38_RS05010XM38_RS05025XM38_RS05030XM38_RS05035XM38_RS05040XM38_RS05045XM38_RS05050
Location: 1085713..1086261 (549 bp)
Type: Others
Protein ID: WP_088429254.1
Location: 1086352..1087104 (753 bp)
Type: Others
Protein ID: WP_080806328.1
Location: 1083379..1083627 (249 bp)
Type: Others
Protein ID: WP_080806320.1
Location: 1083714..1083944 (231 bp)
Type: Others
Protein ID: WP_080806322.1
Location: 1083916..1084926 (1011 bp)
Type: Others
Protein ID: WP_088429252.1
Location: 1084966..1085565 (600 bp)
Type: Others
Protein ID: WP_080806324.1
Location: 1087161..1087856 (696 bp)
Type: Others
Protein ID: WP_088429256.1
Location: 1088031..1088378 (348 bp)
Type: Toxin
Protein ID: WP_080806330.1
Location: 1088372..1088614 (243 bp)
Type: Antitoxin
Protein ID: WP_080806331.1
Location: 1088774..1088959 (186 bp)
Type: Others
Protein ID: WP_088429258.1
Location: 1089108..1091225 (2118 bp)
Type: Others
Protein ID: WP_080806335.1
Location: 1091790..1092188 (399 bp)
Type: Others
Protein ID: WP_088429260.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
XM38_RS049951083379..1083627-249WP_080806320.1hypothetical protein-
XM38_RS050001083714..1083944-231WP_080806322.1transposase-
XM38_RS050051083916..1084926-1011WP_088429252.1pyridoxamine 5'-phosphate oxidase family protein-
XM38_RS050101084966..1085565-600WP_080806324.1glutathione S-transferase-
XM38_RS050151085713..1086261+549WP_088429254.1TetR/AcrR family transcriptional regulator-
XM38_RS050201086352..1087104+753WP_080806328.1aquaporin family protein-
XM38_RS050251087161..1087856-696WP_088429256.1glutathione S-transferase N-terminal domain-containing protein-
XM38_RS050301088031..1088378-348WP_080806330.1endoribonuclease MazFToxin
XM38_RS050351088372..1088614-243WP_080806331.1AbrB/MazE/SpoVT family DNA-binding domain-containing proteinAntitoxin
XM38_RS050401088774..1088959-186WP_088429258.1hypothetical protein-
XM38_RS050451089108..1091225-2118WP_080806335.1tetratricopeptide repeat protein-
XM38_RS050501091790..1092188-399WP_088429260.1rhodanese-like domain-containing protein-

Associated MGEs


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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin

(12-111)

Antitoxin

(7-49)


Sequences


Toxin        


Download         Length: 116 a.a.        Molecular weight: 13207.36 Da        Isoelectric Point: 6.7174

>T78057 WP_080806330.1 NZ_CP021983:c1088378-1088031 [Halomicronema hongdechloris C2206]
MVNPAERYIPDRGHILYLDFNPTKGHEQRGHRPAFVLSPRSYNAKSTLALFMPITRQQKGYPFEVLLPPELQIQGVILVD
QIKCLDWTARNVQFVEIVPDSLVEEVQAKIEPLIL

Download         Length: 348 bp

>T78057 NZ_CP021983:c1088378-1088031 [Halomicronema hongdechloris C2206]
TTGGTAAATCCGGCAGAGCGCTACATTCCTGATAGGGGCCACATCCTTTACCTAGACTTTAATCCAACTAAAGGTCATGA
ACAGCGAGGACACCGACCTGCGTTCGTACTGTCGCCTCGCAGTTACAACGCCAAAAGCACCCTGGCACTGTTTATGCCTA
TTACTAGGCAGCAAAAGGGGTATCCCTTTGAAGTTCTCTTACCGCCTGAACTACAGATTCAAGGGGTGATTCTTGTTGAT
CAGATCAAGTGTCTAGATTGGACAGCCCGTAACGTTCAGTTCGTTGAGATTGTTCCAGATAGCTTAGTTGAAGAGGTGCA
GGCAAAAATCGAACCCCTGATTTTGTAG

Antitoxin


Download         Length: 81 a.a.        Molecular weight: 8787.09 Da        Isoelectric Point: 5.0509

>AT78057 WP_080806331.1 NZ_CP021983:c1088614-1088372 [Halomicronema hongdechloris C2206]
MVATVTKWGNSLALRIPQHIAKEIQLTEGAEVDLAVIDGNLVIKPRPRRRYSLEELIAAITPETLHSEVETGVAVGNEAW

Download         Length: 243 bp

>AT78057 NZ_CP021983:c1088614-1088372 [Halomicronema hongdechloris C2206]
ATGGTTGCGACAGTTACCAAGTGGGGCAATAGTTTGGCCCTTCGGATTCCCCAACACATCGCCAAAGAGATTCAGCTAAC
TGAAGGCGCTGAAGTTGATCTAGCGGTGATTGACGGTAATTTGGTAATCAAACCGAGACCTCGTAGGCGCTATTCTTTAG
AGGAGTTAATAGCGGCTATCACACCAGAGACTTTGCATTCTGAAGTGGAGACTGGAGTCGCTGTGGGGAATGAGGCTTGG
TAA

Similar Proteins


Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures


Toxin

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Source
ID
Structure
No matching records found


Antitoxin

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Source
ID
Structure
No matching records found

References