Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) chpIK/MazF(toxin)
Location 868298..868872 Replicon chromosome
Accession NZ_CP021983
Organism Halomicronema hongdechloris C2206

Toxin (Protein)


Gene name chpK Uniprot ID -
Locus tag XM38_RS04060 Protein ID WP_080809502.1
Coordinates 868298..868642 (-) Length 115 a.a.

Antitoxin (Protein)


Gene name chpI Uniprot ID -
Locus tag XM38_RS04065 Protein ID WP_080809499.1
Coordinates 868636..868872 (-) Length 79 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
XM38_RS04040 863896..864207 - 312 WP_080809508.1 DMT family transporter -
XM38_RS04045 864269..865245 - 977 Protein_807 NAD-dependent epimerase/dehydratase family protein -
XM38_RS04050 865536..866510 - 975 WP_080809588.1 NAD(P)-dependent alcohol dehydrogenase -
XM38_RS04055 867034..868206 + 1173 WP_080809504.1 transposase -
XM38_RS04060 868298..868642 - 345 WP_080809502.1 type II toxin-antitoxin system PemK/MazF family toxin Toxin
XM38_RS04065 868636..868872 - 237 WP_080809499.1 ribbon-helix-helix domain-containing protein Antitoxin
XM38_RS04070 868966..869357 - 392 Protein_812 type II toxin-antitoxin system VapC family toxin -
XM38_RS04075 869344..869589 - 246 WP_080809496.1 AbrB/MazE/SpoVT family DNA-binding domain-containing protein -
XM38_RS04080 870236..870787 - 552 WP_080809494.1 hypothetical protein -
XM38_RS04085 870798..871127 - 330 WP_202978986.1 DUF5615 family PIN-like protein -
XM38_RS04090 871142..871456 - 315 WP_080809488.1 DUF433 domain-containing protein -
XM38_RS04095 871502..871876 - 375 WP_080809485.1 hypothetical protein -
XM38_RS04100 871921..873378 - 1458 WP_080809482.1 IS66 family transposase -
XM38_RS04105 873440..873670 - 231 WP_088429152.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase PemK-like

(1-113)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 115 a.a.        Molecular weight: 12819.84 Da        Isoelectric Point: 4.7204

>T78056 WP_080809502.1 NZ_CP021983:c868642-868298 [Halomicronema hongdechloris C2206]
MVMYRGEIWWANLPDPMGSEPRYRRPVLVIQDDTFTQSQISTVIVVIITSNIRLAEAPGNVLLPHGVSGLSRDSVVNVSQ
IFTIDKTFLVECIGSLPNYLQKEIDEGLRTVLYL

Download         Length: 345 bp

>T78056 NZ_CP021983:c868642-868298 [Halomicronema hongdechloris C2206]
TTGGTAATGTATCGGGGAGAAATTTGGTGGGCGAACCTACCCGATCCAATGGGCTCAGAACCTCGATATCGTCGTCCCGT
CTTGGTGATTCAGGATGATACTTTTACCCAGAGCCAGATTAGCACTGTTATCGTCGTTATTATCACTTCAAATATTCGGT
TAGCGGAAGCACCAGGCAATGTACTGTTACCGCATGGGGTATCGGGTTTGTCGAGAGATTCCGTTGTAAATGTCTCTCAA
ATTTTCACGATCGATAAGACGTTTTTGGTTGAGTGTATTGGTTCGCTACCTAACTACTTGCAGAAGGAGATAGATGAGGG
TTTACGAACAGTTTTGTATCTCTAG

Antitoxin


Download         Length: 79 a.a.        Molecular weight: 9021.40 Da        Isoelectric Point: 6.4599

>AT78056 WP_080809499.1 NZ_CP021983:c868872-868636 [Halomicronema hongdechloris C2206]
MKTAISLPDAVFEQAEVLAQQLGVSRSELYTKALQAYLKRHNRDQILLKLNQVYAKESSELDPVMARMQFMSLPHEDW

Download         Length: 237 bp

>AT78056 NZ_CP021983:c868872-868636 [Halomicronema hongdechloris C2206]
ATGAAAACTGCAATTTCACTTCCAGATGCAGTCTTTGAACAGGCGGAAGTACTTGCTCAGCAGTTAGGGGTGTCACGCAG
TGAGCTTTACACAAAAGCGCTACAGGCATACCTGAAAAGGCACAACCGTGATCAAATCTTGCTCAAATTGAACCAAGTTT
ACGCTAAAGAGTCCTCTGAACTTGATCCAGTTATGGCAAGGATGCAGTTTATGTCTTTGCCCCACGAGGATTGGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References