Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE-RelB
Location 563757..564316 Replicon chromosome
Accession NZ_CP021981
Organism Vibrio anguillarum strain 87-9-116

Toxin (Protein)


Gene name relE Uniprot ID F7YRQ7
Locus tag CEA93_RS17505 Protein ID WP_010320663.1
Coordinates 564038..564316 (+) Length 93 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A233HRF0
Locus tag CEA93_RS17500 Protein ID WP_017040620.1
Coordinates 563757..564041 (+) Length 95 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CEA93_RS17475 560443..560910 - 468 WP_001289286.1 OsmC family protein -
CEA93_RS17480 561067..561507 - 441 WP_040122767.1 hypothetical protein -
CEA93_RS17490 562198..562557 - 360 WP_019281417.1 VOC family protein -
CEA93_RS17500 563757..564041 + 285 WP_017040620.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
CEA93_RS17505 564038..564316 + 279 WP_010320663.1 type II toxin-antitoxin system mRNA interferase toxin, RelE/StbE family Toxin
CEA93_RS17515 565389..565676 - 288 WP_013868556.1 type II toxin-antitoxin system RelE/ParE family toxin -
CEA93_RS17520 565666..565917 - 252 WP_013868555.1 type II toxin-antitoxin system Phd/YefM family antitoxin -
CEA93_RS17530 566131..566616 - 486 WP_107489895.1 hypothetical protein -
CEA93_RS17540 566863..567696 + 834 Protein_529 IS30-like element ISVa6 family transposase -
CEA93_RS17545 567779..568096 + 318 WP_011154648.1 IS66 family insertion sequence hypothetical protein -
CEA93_RS17550 568093..568446 + 354 WP_011154649.1 IS66 family insertion sequence element accessory protein TnpB -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Integron - - 559860..572146 12286


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(2-89)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(5-44)


Sequences

Toxin        


Download         Length: 93 a.a.        Molecular weight: 10878.58 Da        Isoelectric Point: 4.3430

>T78054 WP_010320663.1 NZ_CP021981:564038-564316 [Vibrio anguillarum]
MILWEEESLNDREKIFEFLYDFNPDAAEKTDDIIEAKVENLLEQPLMGVQRDGIRGRLLIIPEISMIVSYWVEGSIIRIM
RVLHQKQKFPTD

Download         Length: 279 bp

>T78054 NZ_CP021981:564038-564316 [Vibrio anguillarum]
ATGATTTTATGGGAAGAGGAATCGCTAAATGATCGTGAGAAGATCTTTGAGTTTCTTTATGACTTTAACCCTGATGCGGC
TGAAAAAACTGATGACATTATTGAGGCTAAAGTAGAAAACTTACTCGAACAACCATTGATGGGTGTTCAACGGGATGGAA
TTCGAGGACGATTACTCATTATTCCCGAAATCTCAATGATCGTTTCGTACTGGGTAGAAGGTTCAATTATTCGCATAATG
CGAGTTCTACACCAGAAGCAGAAATTCCCTACCGATTGA

Antitoxin


Download         Length: 95 a.a.        Molecular weight: 10957.29 Da        Isoelectric Point: 9.2173

>AT78054 WP_017040620.1 NZ_CP021981:563757-564041 [Vibrio anguillarum]
MDTRIQFRVDDEIKRLAQQMAESQGRTLSDACRELTEQMAEQQRKTLSHDAWLTEQINLAFEKFDSGKSSFVEHNSAKAR
MAERKAKIRNRGQQ

Download         Length: 285 bp

>AT78054 NZ_CP021981:563757-564041 [Vibrio anguillarum]
ATGGACACTCGAATTCAATTTCGTGTTGATGACGAAATTAAACGTTTAGCCCAACAAATGGCTGAGAGCCAAGGTCGCAC
ACTCAGCGATGCTTGCCGTGAACTTACTGAACAAATGGCTGAGCAACAAAGAAAAACATTATCTCATGACGCTTGGTTAA
CTGAACAAATAAACCTAGCATTTGAGAAGTTTGACTCAGGAAAATCTTCATTTGTTGAACATAATTCAGCTAAAGCACGA
ATGGCTGAACGAAAGGCCAAAATTCGTAATCGAGGCCAGCAATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0F2IQF3

Antitoxin

Source ID Structure
AlphaFold DB A0A233HRF0

References