Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | /DUF1778(antitoxin) |
| Location | 536816..537777 | Replicon | chromosome |
| Accession | NZ_CP021981 | ||
| Organism | Vibrio anguillarum strain 87-9-116 | ||
Toxin (Protein)
| Gene name | - | Uniprot ID | F7YRB7 |
| Locus tag | CEA93_RS17355 | Protein ID | WP_013868567.1 |
| Coordinates | 536816..537349 (-) | Length | 178 a.a. |
Antitoxin (Protein)
| Gene name | - | Uniprot ID | - |
| Locus tag | CEA93_RS20455 | Protein ID | WP_013868568.1 |
| Coordinates | 537346..537777 (-) | Length | 144 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| CEA93_RS17305 | 532485..532838 | - | 354 | WP_011154649.1 | IS66 family insertion sequence element accessory protein TnpB | - |
| CEA93_RS17310 | 532835..533152 | - | 318 | WP_011154648.1 | IS66 family insertion sequence hypothetical protein | - |
| CEA93_RS17315 | 533310..533966 | - | 657 | WP_013868559.1 | hypothetical protein | - |
| CEA93_RS17320 | 534006..534122 | - | 117 | WP_080749045.1 | DUF3265 domain-containing protein | - |
| CEA93_RS17325 | 534119..534463 | - | 345 | WP_013868560.1 | hypothetical protein | - |
| CEA93_RS17330 | 534614..535162 | - | 549 | WP_019281391.1 | hypothetical protein | - |
| CEA93_RS17335 | 535216..535341 | - | 126 | WP_013868562.1 | DUF3265 domain-containing protein | - |
| CEA93_RS17345 | 535849..536130 | - | 282 | WP_029190024.1 | hypothetical protein | - |
| CEA93_RS17355 | 536816..537349 | - | 534 | WP_013868567.1 | GNAT family N-acetyltransferase | Toxin |
| CEA93_RS20455 | 537346..537777 | - | 432 | WP_013868568.1 | DUF1778 domain-containing protein | Antitoxin |
| CEA93_RS17365 | 538296..538811 | - | 516 | WP_013868571.1 | GNAT family N-acetyltransferase | - |
| CEA93_RS17370 | 538849..538941 | - | 93 | WP_072600976.1 | DUF3265 domain-containing protein | - |
| CEA93_RS17375 | 539056..540024 | + | 969 | WP_076611895.1 | IS30-like element ISVa6 family transposase | - |
| CEA93_RS17380 | 540066..540380 | - | 315 | WP_006073510.1 | hypothetical protein | - |
| CEA93_RS17385 | 540922..542355 | + | 1434 | Protein_506 | DEAD/DEAH box helicase family protein | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | inside | Integron | - | - | 528286..540024 | 11738 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 178 a.a. Molecular weight: 20222.47 Da Isoelectric Point: 9.1188
>T78053 WP_013868567.1 NZ_CP021981:c537349-536816 [Vibrio anguillarum]
VSWGREFVELSKSKHDRDSFDCGEQELNTFIKTQAAKHMQAGISRTMVLPSGQPLLNQKFAICAFYSVAPSSISRETLPT
QLAKKLPRYPIPVFLLAQLAVHKEFHGSGLGKVSLIRALKYLWEVNHHMRAYAIVVDCLTDSAQAFYTKFGFEVLCEHNE
RIRMYLPMKTVEQLFNQ
VSWGREFVELSKSKHDRDSFDCGEQELNTFIKTQAAKHMQAGISRTMVLPSGQPLLNQKFAICAFYSVAPSSISRETLPT
QLAKKLPRYPIPVFLLAQLAVHKEFHGSGLGKVSLIRALKYLWEVNHHMRAYAIVVDCLTDSAQAFYTKFGFEVLCEHNE
RIRMYLPMKTVEQLFNQ
Download Length: 534 bp
>T78053 NZ_CP021981:c537349-536816 [Vibrio anguillarum]
GTGAGTTGGGGCAGAGAGTTTGTAGAACTTAGTAAATCAAAGCATGACCGCGACTCATTTGACTGTGGTGAGCAAGAGCT
AAACACATTTATCAAAACTCAAGCTGCAAAGCACATGCAAGCAGGTATTAGCCGAACAATGGTTTTACCTAGTGGTCAAC
CGCTGTTAAATCAAAAATTCGCTATTTGTGCCTTTTATAGTGTTGCACCGAGCTCAATCAGCCGAGAAACATTACCGACA
CAGTTAGCAAAGAAACTACCGAGATATCCAATCCCTGTTTTTCTGTTGGCTCAATTAGCTGTGCACAAAGAATTTCACGG
TTCTGGACTTGGAAAGGTCAGTCTAATTCGTGCGCTGAAGTACTTGTGGGAAGTAAATCATCACATGAGGGCATACGCAA
TAGTTGTGGATTGTCTGACAGATTCCGCTCAAGCGTTCTATACGAAGTTCGGCTTTGAAGTATTGTGCGAACATAATGAG
CGTATTCGTATGTACTTACCGATGAAAACGGTAGAACAGCTTTTTAATCAATAG
GTGAGTTGGGGCAGAGAGTTTGTAGAACTTAGTAAATCAAAGCATGACCGCGACTCATTTGACTGTGGTGAGCAAGAGCT
AAACACATTTATCAAAACTCAAGCTGCAAAGCACATGCAAGCAGGTATTAGCCGAACAATGGTTTTACCTAGTGGTCAAC
CGCTGTTAAATCAAAAATTCGCTATTTGTGCCTTTTATAGTGTTGCACCGAGCTCAATCAGCCGAGAAACATTACCGACA
CAGTTAGCAAAGAAACTACCGAGATATCCAATCCCTGTTTTTCTGTTGGCTCAATTAGCTGTGCACAAAGAATTTCACGG
TTCTGGACTTGGAAAGGTCAGTCTAATTCGTGCGCTGAAGTACTTGTGGGAAGTAAATCATCACATGAGGGCATACGCAA
TAGTTGTGGATTGTCTGACAGATTCCGCTCAAGCGTTCTATACGAAGTTCGGCTTTGAAGTATTGTGCGAACATAATGAG
CGTATTCGTATGTACTTACCGATGAAAACGGTAGAACAGCTTTTTAATCAATAG
Antitoxin
Download Length: 144 a.a. Molecular weight: 15859.40 Da Isoelectric Point: 7.0831
>AT78053 WP_013868568.1 NZ_CP021981:c537777-537346 [Vibrio anguillarum]
VFTVCFLSSAVRCQPLSRALYSPSFRKLSVRIECALSLAYNRSTDGMYPYAGGVMATARLDIRLDEEIKAKAEKASALLG
LKSLTEYVVRLMDEDATHVIEEHESIMVKDSVFDEFMAACNKVKAPNQALLEAVKFTEKSGIK
VFTVCFLSSAVRCQPLSRALYSPSFRKLSVRIECALSLAYNRSTDGMYPYAGGVMATARLDIRLDEEIKAKAEKASALLG
LKSLTEYVVRLMDEDATHVIEEHESIMVKDSVFDEFMAACNKVKAPNQALLEAVKFTEKSGIK
Download Length: 432 bp
>AT78053 NZ_CP021981:c537777-537346 [Vibrio anguillarum]
GTGTTTACAGTGTGTTTTTTGAGTTCGGCGGTGCGTTGTCAACCCCTTAGCCGGGCGTTATATTCTCCCTCGTTCCGTAA
ACTTTCCGTACGAATTGAATGTGCTTTAAGTTTGGCCTATAATCGCTCAACTGACGGAATGTATCCGTATGCAGGAGGGG
TTATGGCAACGGCACGTTTAGATATCCGCCTTGATGAAGAGATCAAGGCAAAAGCCGAAAAGGCATCGGCTTTACTTGGC
TTAAAAAGTCTCACTGAATACGTGGTGAGACTTATGGACGAAGATGCGACTCATGTTATTGAGGAGCATGAAAGTATTAT
GGTTAAAGACAGTGTTTTTGACGAGTTTATGGCTGCGTGTAATAAAGTAAAAGCACCGAATCAAGCTTTGCTTGAAGCTG
TTAAATTTACAGAGAAGAGCGGTATCAAGTGA
GTGTTTACAGTGTGTTTTTTGAGTTCGGCGGTGCGTTGTCAACCCCTTAGCCGGGCGTTATATTCTCCCTCGTTCCGTAA
ACTTTCCGTACGAATTGAATGTGCTTTAAGTTTGGCCTATAATCGCTCAACTGACGGAATGTATCCGTATGCAGGAGGGG
TTATGGCAACGGCACGTTTAGATATCCGCCTTGATGAAGAGATCAAGGCAAAAGCCGAAAAGGCATCGGCTTTACTTGGC
TTAAAAAGTCTCACTGAATACGTGGTGAGACTTATGGACGAAGATGCGACTCATGTTATTGAGGAGCATGAAAGTATTAT
GGTTAAAGACAGTGTTTTTGACGAGTTTATGGCTGCGTGTAATAAAGTAAAAGCACCGAATCAAGCTTTGCTTGAAGCTG
TTAAATTTACAGAGAAGAGCGGTATCAAGTGA
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|