Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 5138322..5138467 Replicon chromosome
Accession NZ_CP021960
Organism Klebsiella pneumoniae strain AR_0139

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 5138329..5138431 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 5138322..5138467 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
AM386_RS27590 5133855..5135288 + 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
AM386_RS27595 5135404..5135643 + 240 WP_002911393.1 YebV family protein -
AM386_RS27600 5135741..5135932 + 192 WP_002911395.1 YebW family protein -
AM386_RS27605 5135929..5136582 - 654 WP_071570906.1 protein-serine/threonine phosphatase -
AM386_RS27610 5136739..5137707 + 969 WP_168786284.1 VirK/YbjX family protein -
AM386_RS31340 5137812..5137955 + 144 WP_002911398.1 Ecr family regulatory small membrane protein -
- 5138322..5138467 + 146 - - Antitoxin
- 5138329..5138431 - 103 - - Toxin
AM386_RS27620 5138590..5138928 - 339 WP_004189269.1 YebY family protein -
AM386_RS27625 5138945..5139814 - 870 WP_004189267.1 copper homeostasis membrane protein CopD -
AM386_RS27630 5139818..5140192 - 375 WP_004151448.1 CopC domain-containing protein YobA -
AM386_RS27635 5140305..5140535 + 231 WP_002911406.1 DNA polymerase III subunit theta -
AM386_RS27640 5140614..5141273 + 660 WP_002911407.1 exodeoxyribonuclease X -
AM386_RS27645 5141277..5143337 - 2061 WP_004151449.1 oligopeptidase B -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T78022 NZ_CP021960:c5138431-5138329 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT78022 NZ_CP021960:5138322-5138467 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References