Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 3337823..3337968 Replicon chromosome
Accession NZ_CP021955
Organism Klebsiella pneumoniae strain AR_0107

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 3337830..3337932 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 3337823..3337968 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
AM486_RS17015 3333356..3334789 + 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
AM486_RS17020 3334905..3335144 + 240 WP_002911393.1 YebV family protein -
AM486_RS17025 3335242..3335433 + 192 WP_002911395.1 YebW family protein -
AM486_RS17030 3335430..3336083 - 654 WP_020802220.1 protein-serine/threonine phosphatase -
AM486_RS17035 3336240..3337208 + 969 WP_004151446.1 VirK/YbjX family protein -
AM486_RS29135 3337313..3337456 + 144 WP_002911398.1 Ecr family regulatory small membrane protein -
- 3337823..3337968 + 146 - - Antitoxin
- 3337830..3337932 - 103 - - Toxin
AM486_RS17045 3338091..3338429 - 339 WP_016529031.1 YebY family protein -
AM486_RS17050 3338446..3339315 - 870 WP_004189267.1 copper homeostasis membrane protein CopD -
AM486_RS17055 3339319..3339693 - 375 WP_004151448.1 CopC domain-containing protein YobA -
AM486_RS17060 3339806..3340036 + 231 WP_002911406.1 DNA polymerase III subunit theta -
AM486_RS17065 3340115..3340774 + 660 WP_002911407.1 exodeoxyribonuclease X -
AM486_RS17070 3340778..3342838 - 2061 WP_048289976.1 oligopeptidase B -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T77994 NZ_CP021955:c3337932-3337830 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT77994 NZ_CP021955:3337823-3337968 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References