Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 5250108..5250252 Replicon chromosome
Accession NZ_CP021950
Organism Klebsiella pneumoniae strain AR_0148

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 5250144..5250246 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 5250108..5250252 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
AM395_RS26370 5245238..5247298 + 2061 WP_004151449.1 oligopeptidase B -
AM395_RS26375 5247302..5247961 - 660 WP_002911407.1 exodeoxyribonuclease X -
AM395_RS26380 5248040..5248270 - 231 WP_002911406.1 DNA polymerase III subunit theta -
AM395_RS26385 5248383..5248757 + 375 WP_004151448.1 CopC domain-containing protein YobA -
AM395_RS26390 5248761..5249630 + 870 WP_020956678.1 copper homeostasis membrane protein CopD -
AM395_RS26395 5249647..5249985 + 339 WP_002911404.1 YebY family protein -
- 5250108..5250252 - 145 - - Antitoxin
- 5250144..5250246 + 103 - - Toxin
AM395_RS26400 5250379..5250738 - 360 WP_077253379.1 tyrosine-type recombinase/integrase -
AM395_RS26405 5250737..5251216 + 480 WP_032419797.1 lysis protein -
AM395_RS26415 5252382..5253509 + 1128 WP_064147220.1 hypothetical protein -
AM395_RS26420 5253759..5254187 - 429 WP_032419788.1 type II toxin-antitoxin system PemK/MazF family toxin -
AM395_RS26425 5254197..5254478 - 282 WP_032419786.1 hypothetical protein -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T77977 NZ_CP021950:5250144-5250246 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 145 bp

>AT77977 NZ_CP021950:c5250252-5250108 [Klebsiella pneumoniae]
ACATATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGT
TGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References