Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 286097..286242 Replicon chromosome
Accession NZ_CP021944
Organism Klebsiella pneumoniae strain AR_0152

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 286104..286206 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 286097..286242 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
AM399_RS01525 281628..283061 + 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
AM399_RS01530 283177..283416 + 240 WP_002911393.1 YebV family protein -
AM399_RS01535 283514..283705 + 192 WP_002911395.1 YebW family protein -
AM399_RS01540 283702..284355 - 654 WP_024622748.1 protein-serine/threonine phosphatase -
AM399_RS01545 284512..285480 + 969 WP_014907334.1 VirK/YbjX family protein -
AM399_RS29145 285585..285728 + 144 WP_038431282.1 Ecr family regulatory small membrane protein -
- 286097..286242 + 146 - - Antitoxin
- 286104..286206 - 103 - - Toxin
AM399_RS01555 286365..286703 - 339 WP_002911404.1 YebY family protein -
AM399_RS01560 286720..287589 - 870 WP_004175431.1 copper homeostasis membrane protein CopD -
AM399_RS01565 287593..287967 - 375 WP_039819395.1 CopC domain-containing protein YobA -
AM399_RS01570 288080..288310 + 231 WP_002911406.1 DNA polymerase III subunit theta -
AM399_RS01575 288389..289048 + 660 WP_002911407.1 exodeoxyribonuclease X -
AM399_RS01580 289052..291112 - 2061 WP_004151449.1 oligopeptidase B -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T77947 NZ_CP021944:c286206-286104 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT77947 NZ_CP021944:286097-286242 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References