Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapC-mazE/VapC-MazE
Location 81022..81683 Replicon plasmid pAP1468-2
Accession NZ_CP021924
Organism Acetobacter pasteurianus subsp. Pasteurianus strain SRCM101468

Toxin (Protein)


Gene name vapC Uniprot ID C7JIL1
Locus tag S101468_RS15515 Protein ID WP_006115553.1
Coordinates 81022..81330 (+) Length 103 a.a.

Antitoxin (Protein)


Gene name mazE Uniprot ID C7JIL0
Locus tag S101468_RS15520 Protein ID WP_006115554.1
Coordinates 81429..81683 (+) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
S101468_RS15480 76375..76524 - 150 WP_007397858.1 DUF2474 domain-containing protein -
S101468_RS15485 76511..77530 - 1020 WP_006115550.1 cytochrome d ubiquinol oxidase subunit II -
S101468_RS15490 77533..78966 - 1434 WP_006115551.1 cytochrome ubiquinol oxidase subunit I -
S101468_RS15500 79402..80362 - 961 Protein_70 IS481 family transposase -
S101468_RS15505 80420..80680 + 261 Protein_71 hypothetical protein -
S101468_RS15510 80753..81025 + 273 WP_006115552.1 AbrB/MazE/SpoVT family DNA-binding domain-containing protein -
S101468_RS15515 81022..81330 + 309 WP_006115553.1 PIN domain-containing protein Toxin
S101468_RS15520 81429..81683 + 255 WP_006115554.1 AbrB/MazE/SpoVT family DNA-binding domain-containing protein Antitoxin
S101468_RS15525 81685..82014 + 330 WP_012813213.1 endoribonuclease MazF -
S101468_RS15530 82071..82271 + 201 WP_012813212.1 hypothetical protein -
S101468_RS15535 82301..82621 + 321 WP_012813211.1 hypothetical protein -
S101468_RS15540 82678..83082 - 405 WP_006115557.1 hypothetical protein -
S101468_RS15545 83095..83910 - 816 WP_012813210.1 hypothetical protein -
S101468_RS16770 83995..84180 + 186 WP_041633309.1 hypothetical protein -
S101468_RS15555 84232..85415 + 1184 WP_088365127.1 IS3 family transposase -
S101468_RS15560 85622..85900 + 279 WP_006115563.1 HU family DNA-binding protein -
S101468_RS15565 85979..86197 + 219 WP_170315285.1 WGR domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..184348 184348


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-73)

Antitoxin

Toxin YoeB

(5-84)


Sequences

Toxin        


Download         Length: 103 a.a.        Molecular weight: 13219.95 Da        Isoelectric Point: 12.8085

>T77877 WP_006115553.1 NZ_CP021924:81022-81330 [Acetobacter pasteurianus subsp. Pasteurianus]
KKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKK
KKKKKKKKKKKKKKKKKKKKKKK

Download         Length: 309 bp

>T77877 NZ_CP021924:81022-81330 [Acetobacter pasteurianus subsp. Pasteurianus]
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 10912.81 Da        Isoelectric Point: 12.7242

>AT77877 WP_006115554.1 NZ_CP021924:81429-81683 [Acetobacter pasteurianus subsp. Pasteurianus]
KKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKK
KKKKK

Download         Length: 255 bp

>AT77877 NZ_CP021924:81429-81683 [Acetobacter pasteurianus subsp. Pasteurianus]
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A401X8Y0

Antitoxin

Source ID Structure
AlphaFold DB A0A6P1QDC4

References