Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) spoIISABC/SpoIISA-SpoIISB
Location 3296093..3297012 Replicon chromosome
Accession NZ_CP021920
Organism Bacillus sonorensis strain SRCM101395

Toxin (Protein)


Gene name spoIISA Uniprot ID M5PDF4
Locus tag S101395_RS17310 Protein ID WP_006638546.1
Coordinates 3296093..3296839 (+) Length 249 a.a.

Antitoxin (Protein)


Gene name spoIISB Uniprot ID A0A7Y8RVI2
Locus tag S101395_RS17315 Protein ID WP_029418621.1
Coordinates 3296839..3297012 (+) Length 58 a.a.

Genomic Context

S101395_RS17300S101395_RS17305S101395_RS17310S101395_RS17315S101395_RS17295S101395_RS17320S101395_RS17325S101395_RS17330S101395_RS17335
Location: 3294352..3294969 (618 bp)
Type: Others
Protein ID: WP_006638544.1
Location: 3294982..3295980 (999 bp)
Type: Others
Protein ID: WP_006638545.1
Location: 3296093..3296839 (747 bp)
Type: Toxin
Protein ID: WP_006638546.1
Location: 3296839..3297012 (174 bp)
Type: Antitoxin
Protein ID: WP_029418621.1
Location: 3292264..3294024 (1761 bp)
Type: Others
Protein ID: WP_006638543.1
Location: 3297312..3298580 (1269 bp)
Type: Others
Protein ID: WP_006638548.1
Location: 3298608..3299624 (1017 bp)
Type: Others
Protein ID: WP_006638549.1
Location: 3299644..3300492 (849 bp)
Type: Others
Protein ID: WP_006638550.1
Location: 3300468..3301565 (1098 bp)
Type: Others
Protein ID: WP_006638551.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
S101395_RS172953292264..3294024-1761WP_006638543.1gamma-glutamyltransferase-
S101395_RS173003294352..3294969+618WP_006638544.1DUF47 domain-containing protein-
S101395_RS173053294982..3295980+999WP_006638545.1inorganic phosphate transporter-
S101395_RS173103296093..3296839+747WP_006638546.1type II toxin-antitoxin system SpoIISA family toxinToxin
S101395_RS173153296839..3297012+174WP_029418621.1type II toxin-antitoxin system SpoIISB family antitoxinAntitoxin
S101395_RS173203297312..3298580-1269WP_006638548.1MFS transporter-
S101395_RS173253298608..3299624-1017WP_006638549.1zinc-binding alcohol dehydrogenase family protein-
S101395_RS173303299644..3300492-849WP_006638550.1SDR family oxidoreductase-
S101395_RS173353300468..3301565-1098WP_006638551.1mannonate dehydratase-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin SpoIISA, type II toxin-antitoxin system

(3-238)

Antitoxin

Antitoxin SpoIISB

(1-57)


Sequences

Toxin        


Download         Length: 249 a.a.        Molecular weight: 29647.11 Da        Isoelectric Point: 4.6172

>T77872 WP_006638546.1 NZ_CP021920:3296093-3296839 [Bacillus sonorensis]
MLLFYQFSVWVIVLALALYVFAVWRFEKKMKEKTIAIRKTWYLLYVIGAVIYWTYNPQSLFTDPLHYLIVAVFFTLTDAF
IFLNAYFKKLGSNELATDTRELLEENNDLLHTYQNRLKTFQYLLKNEPIHIYYGDIEAYAEGIEKLIKRFAEKMNISASL
CEYNSEQSKDHLLEHMENRFAVQEKLERKDVYYEENGKMVLIPFSIHEYDYVMKLTSEDLVTEFDYLLFTSLTSIYDLLL
PYEEEGDE

Download         Length: 747 bp

>T77872 NZ_CP021920:3296093-3296839 [Bacillus sonorensis]
ATGCTGCTTTTTTATCAATTCTCAGTTTGGGTTATCGTTCTGGCTTTGGCTCTGTACGTTTTTGCCGTGTGGCGCTTTGA
AAAAAAGATGAAAGAAAAAACGATTGCCATCCGGAAAACCTGGTATCTCCTTTATGTAATCGGCGCCGTGATTTACTGGA
CGTACAATCCGCAGTCCCTTTTTACAGACCCGCTTCATTATCTGATCGTCGCCGTTTTTTTCACGCTGACCGATGCATTT
ATTTTCTTAAACGCCTACTTTAAAAAACTGGGCAGCAATGAACTGGCGACAGACACAAGAGAGCTGCTCGAAGAAAACAA
CGACCTGCTTCACACCTATCAAAACAGGCTGAAAACGTTCCAATACCTATTGAAAAACGAACCGATTCACATCTATTATG
GAGATATAGAAGCTTATGCAGAAGGCATTGAAAAACTCATTAAACGGTTTGCCGAAAAAATGAATATATCTGCCTCACTC
TGTGAATATAATTCAGAGCAGAGCAAAGATCATTTGCTTGAACACATGGAAAACCGTTTCGCTGTTCAGGAAAAGCTGGA
GCGAAAAGATGTATATTACGAAGAAAACGGAAAAATGGTCCTGATTCCATTTTCTATCCATGAATACGACTATGTCATGA
AACTGACTTCCGAGGACCTTGTCACTGAATTTGATTATCTTCTGTTTACTTCTTTAACGAGCATCTATGATCTCCTGCTA
CCATACGAAGAGGAAGGTGACGAATGA

Antitoxin


Download         Length: 58 a.a.        Molecular weight: 6961.93 Da        Isoelectric Point: 10.7390

>AT77872 WP_029418621.1 NZ_CP021920:3296839-3297012 [Bacillus sonorensis]
MEPVFQHDEDRSIKRGAWKVFKKQSRTNIAKYELSPHTERIFRQNARLIDEYKRKNA

Download         Length: 174 bp

>AT77872 NZ_CP021920:3296839-3297012 [Bacillus sonorensis]
ATGGAGCCGGTTTTTCAGCACGACGAAGACCGTTCAATCAAGCGCGGCGCGTGGAAAGTATTTAAAAAACAATCGAGAAC
AAATATCGCCAAATATGAACTCAGCCCTCATACCGAACGGATTTTCAGACAAAATGCACGGCTGATTGATGAGTATAAAC
GAAAAAATGCCTGA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
AlphaFold DBM5PDF4

Antitoxin

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Source
ID
Structure
AlphaFold DBA0A7Y8RVI2

References