Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1109036..1109181 Replicon chromosome
Accession NZ_CP021859
Organism Klebsiella pneumoniae strain AR_0125

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1109043..1109145 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1109036..1109181 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
AM372_RS07500 1104568..1106001 + 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
AM372_RS07505 1106117..1106356 + 240 WP_002911393.1 YebV family protein -
AM372_RS07510 1106454..1106645 + 192 WP_002911395.1 YebW family protein -
AM372_RS07515 1106642..1107295 - 654 WP_002911396.1 protein-serine/threonine phosphatase -
AM372_RS07520 1107452..1108420 + 969 WP_004151446.1 VirK/YbjX family protein -
AM372_RS29385 1108525..1108668 + 144 WP_002911398.1 Ecr family regulatory small membrane protein -
- 1109036..1109181 + 146 - - Antitoxin
- 1109043..1109145 - 103 - - Toxin
AM372_RS07530 1109304..1109642 - 339 WP_002911404.1 YebY family protein -
AM372_RS07535 1109659..1110528 - 870 WP_004151447.1 copper homeostasis membrane protein CopD -
AM372_RS07540 1110532..1110906 - 375 WP_004151448.1 CopC domain-containing protein YobA -
AM372_RS07545 1111019..1111249 + 231 WP_002911406.1 DNA polymerase III subunit theta -
AM372_RS07550 1111328..1111987 + 660 WP_002911407.1 exodeoxyribonuclease X -
AM372_RS07555 1111991..1114051 - 2061 WP_004151449.1 oligopeptidase B -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T77698 NZ_CP021859:c1109145-1109043 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT77698 NZ_CP021859:1109036-1109181 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References