Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) mazEF/PRK09907-MazE
Location 1301462..1302096 Replicon chromosome
Accession NZ_CP021850
Organism Pseudoclostridium thermosuccinogenes strain DSM 5807

Toxin (Protein)


Gene name mazF Uniprot ID -
Locus tag CDO33_RS05615 Protein ID WP_103080159.1
Coordinates 1301462..1301845 (-) Length 128 a.a.

Antitoxin (Protein)


Gene name mazE Uniprot ID -
Locus tag CDO33_RS05620 Protein ID WP_202849473.1
Coordinates 1301845..1302096 (-) Length 84 a.a.

Genomic Context

CDO33_RS05600CDO33_RS05610CDO33_RS05605CDO33_RS05615CDO33_RS05620CDO33_RS05625CDO33_RS05630CDO33_RS05635CDO33_RS05640CDO33_RS20770
Location: 1297191..1298858 (1668 bp)
Type: Others
Protein ID: WP_103080156.1
Location: 1300646..1301089 (444 bp)
Type: Others
Protein ID: WP_103080158.1
Location: 1298924..1300183 (1260 bp)
Type: Others
Protein ID: WP_103080157.1
Location: 1301462..1301845 (384 bp)
Type: Toxin
Protein ID: WP_103080159.1
Location: 1301845..1302096 (252 bp)
Type: Antitoxin
Protein ID: WP_202849473.1
Location: 1302577..1302696 (120 bp)
Type: Others
Protein ID: WP_103080161.1
Location: 1302699..1303517 (819 bp)
Type: Others
Protein ID: WP_133158673.1
Location: 1303881..1304000 (120 bp)
Type: Others
Protein ID: WP_103080163.1
Location: 1304002..1304970 (969 bp)
Type: Others
Protein ID: WP_133158674.1
Location: 1305520..1306554 (1035 bp)
Type: Others
Protein ID: WP_161496430.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
CDO33_RS056001297191..1298858+1668WP_103080156.1ribonuclease J-
CDO33_RS056051298924..1300183-1260WP_103080157.1nucleotidyltransferase-
CDO33_RS056101300646..1301089+444WP_103080158.1DUF2383 domain-containing protein-
CDO33_RS056151301462..1301845-384WP_103080159.1type II toxin-antitoxin system PemK/MazF family toxinToxin
CDO33_RS056201301845..1302096-252WP_202849473.1AbrB/MazE/SpoVT family DNA-binding domain-containing proteinAntitoxin
CDO33_RS056251302577..1302696-120WP_103080161.1cyclic lactone autoinducer peptide-
CDO33_RS056301302699..1303517-819WP_133158673.1hypothetical protein-
CDO33_RS056351303881..1304000-120WP_103080163.1cyclic lactone autoinducer peptide-
CDO33_RS056401304002..1304970-969WP_133158674.1hypothetical protein-
CDO33_RS207701305520..1306554-1035WP_161496430.1hypothetical protein-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase PemK-like

(6-116)

Antitoxin

Antitoxin PemI-like

(4-81)


Sequences

Toxin        


Download         Length: 128 a.a.        Molecular weight: 14016.11 Da        Isoelectric Point: 5.8508

>T77665 WP_103080159.1 NZ_CP021850:c1301845-1301462 [Pseudoclostridium thermosuccinogenes]
MADIPERGAFIVLNFNPQAGHEQAGRRNAIVLSPKEFNRKTGFVVVCPITNQKKGYPFEVDLPVNGIFLDSGGSPITGVI
LTDQVKSLDWTARNIKILKNYDPNDAQIKEIDAIIDECLAKIATYLT

Download         Length: 384 bp

>T77665 NZ_CP021850:c1301845-1301462 [Pseudoclostridium thermosuccinogenes]
ATGGCAGATATACCTGAGAGAGGTGCTTTTATTGTTTTAAACTTTAATCCACAAGCTGGTCATGAGCAAGCTGGGAGAAG
GAATGCTATTGTTTTATCACCTAAAGAATTCAATAGAAAAACAGGATTTGTAGTTGTTTGTCCGATCACTAATCAGAAGA
AGGGATATCCTTTTGAAGTGGACTTACCAGTTAATGGGATATTCCTTGATAGTGGTGGCAGCCCAATAACAGGGGTAATT
TTAACTGATCAAGTTAAATCATTGGATTGGACAGCCCGTAATATAAAAATATTGAAAAACTACGATCCAAATGATGCACA
AATAAAAGAAATAGATGCAATAATTGATGAATGTCTAGCTAAAATAGCCACATACCTTACATAA

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9370.77 Da        Isoelectric Point: 5.1667

>AT77665 WP_202849473.1 NZ_CP021850:c1302096-1301845 [Pseudoclostridium thermosuccinogenes]
MATVIAQKWGNSLGIRIPKEAAEKVGIKQGSEIELIIAENDEIITLKPKRLQKKYTLEDLLSQITPENRHNEIDFGSEGR
ELI

Download         Length: 252 bp

>AT77665 NZ_CP021850:c1302096-1301845 [Pseudoclostridium thermosuccinogenes]
ATGGCTACAGTCATTGCCCAAAAGTGGGGAAACAGCTTGGGAATACGTATTCCAAAAGAAGCTGCCGAGAAAGTAGGCAT
CAAACAAGGTTCCGAAATTGAATTGATTATTGCTGAAAACGATGAAATCATCACATTAAAACCAAAAAGATTACAAAAGA
AATACACATTAGAAGATCTTTTATCACAAATTACTCCTGAAAACCGACACAATGAAATTGATTTTGGAAGCGAAGGGCGT
GAATTAATTTAA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
No matching records found

Antitoxin

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Source
ID
Structure
No matching records found

References