Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 4375058..4375329 Replicon chromosome
Accession NZ_CP021840
Organism Escherichia coli strain EC974

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 4375096..4375199 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 4375058..4375329 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CDH88_RS21915 4372216..4373655 + 1440 WP_024248364.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
CDH88_RS21920 4373772..4374008 + 237 WP_001295499.1 DUF1480 family protein -
CDH88_RS21925 4374113..4374304 + 192 WP_001296140.1 YebW family protein -
CDH88_RS21930 4374305..4374961 - 657 WP_088172433.1 protein-serine/threonine phosphatase -
- 4375058..4375329 + 272 - - Antitoxin
- 4375096..4375199 - 104 - - Toxin
CDH88_RS21935 4375357..4375698 - 342 WP_000976472.1 YebY family protein -
CDH88_RS21940 4375711..4376583 - 873 WP_000879298.1 copper homeostasis membrane protein CopD -
CDH88_RS21945 4376587..4376961 - 375 WP_021577594.1 CopC domain-containing protein YobA -
CDH88_RS21950 4377100..4377330 + 231 WP_000916763.1 DNA polymerase III subunit theta -
CDH88_RS21955 4377432..4378088 + 657 WP_021577595.1 carbon-nitrogen hydrolase family protein -
CDH88_RS21960 4378111..4378773 + 663 WP_088172434.1 exodeoxyribonuclease X -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T77605 NZ_CP021840:c4375199-4375096 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT77605 NZ_CP021840:4375058-4375329 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References