Detailed information of TA system
Overview
TA module
| Type | VIII | Classification (family/domain) | SdsR-RyeA/- |
| Location | 2025399..2025544 | Replicon | chromosome |
| Accession | NZ_CP021833 | ||
| Organism | Klebsiella pneumoniae strain AR_0120 | ||
Toxin (RNA)
| Gene name | SdsR | ||
| Locus tag | - | ||
| Coordinates | 2025406..2025508 (-) |
Antitoxin (RNA)
| Gene name | RyeA | ||
| Locus tag | - | ||
| Coordinates | 2025399..2025544 (+) |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| AM367_RS10275 | 2020931..2022364 | + | 1434 | WP_004148845.1 | 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF | - |
| AM367_RS10280 | 2022480..2022719 | + | 240 | WP_002911393.1 | YebV family protein | - |
| AM367_RS10285 | 2022817..2023008 | + | 192 | WP_002911395.1 | YebW family protein | - |
| AM367_RS10290 | 2023005..2023658 | - | 654 | WP_002911396.1 | protein-serine/threonine phosphatase | - |
| AM367_RS10295 | 2023815..2024783 | + | 969 | WP_004151446.1 | VirK/YbjX family protein | - |
| AM367_RS30780 | 2024888..2025031 | + | 144 | WP_002911398.1 | Ecr family regulatory small membrane protein | - |
| - | 2025399..2025544 | + | 146 | - | - | Antitoxin |
| - | 2025406..2025508 | - | 103 | - | - | Toxin |
| AM367_RS10305 | 2025667..2026005 | - | 339 | WP_002911404.1 | YebY family protein | - |
| AM367_RS10310 | 2026022..2026891 | - | 870 | WP_004151447.1 | copper homeostasis membrane protein CopD | - |
| AM367_RS10315 | 2026895..2027269 | - | 375 | WP_004151448.1 | CopC domain-containing protein YobA | - |
| AM367_RS10320 | 2027382..2027612 | + | 231 | WP_002911406.1 | DNA polymerase III subunit theta | - |
| AM367_RS10325 | 2027691..2028350 | + | 660 | WP_002911407.1 | exodeoxyribonuclease X | - |
| AM367_RS10330 | 2028354..2030414 | - | 2061 | WP_004151449.1 | oligopeptidase B | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 103 bp
>T77567 NZ_CP021833:c2025508-2025406 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT
Antitoxin
Download Length: 146 bp
>AT77567 NZ_CP021833:2025399-2025544 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT
