Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE-RelB
Location 126392..126990 Replicon plasmid psymA
Accession NZ_CP021824
Organism Sinorhizobium meliloti strain KH46

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag CDO24_RS27120 Protein ID WP_013845238.1
Coordinates 126697..126990 (+) Length 98 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag CDO24_RS27115 Protein ID WP_014989717.1
Coordinates 126392..126700 (+) Length 103 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CDO24_RS27080 121477..123003 + 1527 WP_088200012.1 amidohydrolase -
CDO24_RS27090 124249..124572 - 324 WP_003526806.1 DNA-binding transcriptional regulator -
CDO24_RS27095 124562..124916 - 355 Protein_124 type II toxin-antitoxin system RelE/ParE family toxin -
CDO24_RS35110 125273..126175 + 903 Protein_125 ParB N-terminal domain-containing protein -
CDO24_RS27115 126392..126700 + 309 WP_014989717.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
CDO24_RS27120 126697..126990 + 294 WP_013845238.1 type II toxin-antitoxin system mRNA interferase toxin, RelE/StbE family Toxin
CDO24_RS27125 127252..128451 - 1200 WP_164828738.1 NAD-dependent formate dehydrogenase -
CDO24_RS27130 128845..129617 + 773 Protein_129 ParB N-terminal domain-containing protein -
CDO24_RS27135 129741..130412 - 672 Protein_130 inositol monophosphatase family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Conjugative plasmid - htpB 1..1597380 1597380


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-90)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(1-53)


Sequences

Toxin        


Download         Length: 98 a.a.        Molecular weight: 11202.84 Da        Isoelectric Point: 6.4735

>T77534 WP_013845238.1 NZ_CP021824:126697-126990 [Sinorhizobium meliloti]
MRLVWARYALDDRDTIFSSIERENPRAAVHVDEEIVSAVRRLLDFPESGRPGRIAGTRELVIPRTPYIAAYMVMEDRIRI
LRVLHGAQKWPSELDDG

Download         Length: 294 bp

>T77534 NZ_CP021824:126697-126990 [Sinorhizobium meliloti]
ATGAGGCTCGTCTGGGCGCGATATGCGCTTGACGATCGCGACACCATCTTCAGTTCCATCGAAAGGGAGAATCCGAGGGC
GGCGGTCCACGTCGACGAGGAGATCGTCAGCGCGGTACGTCGTCTGCTTGATTTTCCGGAAAGCGGCCGCCCTGGCCGGA
TTGCCGGAACTCGAGAGCTTGTTATCCCTCGGACCCCCTACATTGCAGCCTACATGGTAATGGAGGATAGAATTCGAATT
CTGCGTGTCCTGCACGGCGCCCAGAAGTGGCCCAGCGAGCTCGACGACGGGTAG

Antitoxin


Download         Length: 103 a.a.        Molecular weight: 11228.61 Da        Isoelectric Point: 5.6604

>AT77534 WP_014989717.1 NZ_CP021824:126392-126700 [Sinorhizobium meliloti]
MASNALVQTRIDAEVKERATAVLENMGLTVSDAVRILLTRTANEGALPLELFSHSEAHDAWFRAKVLRALEDTRPDVDDA
DADAHFRERRAAAMRKAAAGDR

Download         Length: 309 bp

>AT77534 NZ_CP021824:126392-126700 [Sinorhizobium meliloti]
ATGGCTTCAAATGCACTTGTTCAGACTCGAATCGATGCCGAGGTCAAAGAGCGCGCCACGGCGGTTTTAGAGAACATGGG
TCTGACGGTCTCGGACGCTGTTCGAATCCTGTTAACTCGGACGGCGAATGAGGGCGCCCTGCCGCTGGAACTCTTCAGCC
ACAGCGAGGCGCACGACGCTTGGTTCCGCGCCAAAGTGTTGCGGGCACTCGAGGATACCCGACCCGACGTCGACGATGCC
GACGCCGATGCGCACTTTCGAGAGCGCCGGGCGGCAGCTATGCGCAAGGCTGCGGCGGGTGATCGATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References