Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) rlegTA/AbiEii(toxin)
Location 3757330..3758809 Replicon chromosome
Accession NZ_CP021804
Organism Sinorhizobium meliloti strain T073

Toxin (Protein)


Gene name rlegT Uniprot ID -
Locus tag CDO28_RS18555 Protein ID WP_088195685.1
Coordinates 3757940..3758809 (+) Length 290 a.a.

Antitoxin (Protein)


Gene name rlegA Uniprot ID -
Locus tag CDO28_RS18550 Protein ID WP_094182592.1
Coordinates 3757330..3757947 (+) Length 206 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CDO28_RS18540 3752654..3753574 + 921 WP_088195683.1 hypothetical protein -
CDO28_RS18545 3753575..3757168 + 3594 WP_088195684.1 DEAD/DEAH box helicase -
CDO28_RS18550 3757330..3757947 + 618 WP_094182592.1 type IV toxin-antitoxin system AbiEi family antitoxin domain-containing protein Antitoxin
CDO28_RS18555 3757940..3758809 + 870 WP_088195685.1 nucleotidyl transferase AbiEii/AbiGii toxin family protein Toxin
CDO28_RS18560 3759089..3760159 - 1071 WP_088195686.1 site-specific integrase -
CDO28_RS18565 3760274..3761419 + 1146 WP_088195687.1 tRNA dihydrouridine(20/20a) synthase DusA -
CDO28_RS18570 3761547..3761759 - 213 WP_003535347.1 cold-shock protein -
CDO28_RS18585 3762591..3763208 + 618 WP_010969551.1 J domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Integrative and Conjugative Element - - 3731388..3760159 28771


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Nucleotidyl transferase AbiEii toxin, Type IV TA system

(38-261)

Antitoxin

Transcriptional regulator, AbiEi antitoxin

(16-55)


Sequences

Toxin        


Download         Length: 290 a.a.        Molecular weight: 32463.27 Da        Isoelectric Point: 5.2700

>T77471 WP_088195685.1 NZ_CP021804:3757940-3758809 [Sinorhizobium meliloti]
MAKEIKNIGASVRARLLQVAKVSGQSFDLVLTRFALERLLFRLSQSPHADRFVLKGAMLMMSWFDDPHRGTRDLDLLGFG
DPSPEPMLATFREILAQDAGDGVEFDADALRVDRIREELEYGGLRLRTTGSISGARISLTIDIGFGDALEPGAEELEYPS
MLDFPIPRLRGYARETVIAEKFQAMVALGRANTRMKDFYDIWILSRSFEFGNDRLMRAIIATFERRETPIPTVLPDALTE
AFAKDQQKQRQWRAFVEDVAHNPGELMDVITDIAAFLMPHAVVAASRGK

Download         Length: 870 bp

>T77471 NZ_CP021804:3757940-3758809 [Sinorhizobium meliloti]
ATGGCTAAAGAGATCAAGAACATTGGCGCCTCGGTGCGCGCACGTCTGCTGCAGGTCGCCAAGGTAAGTGGCCAGAGCTT
CGATCTGGTTCTGACCCGCTTCGCCCTCGAGCGGCTGCTTTTCCGGCTTAGCCAGTCACCCCACGCCGACCGCTTCGTGC
TGAAGGGCGCGATGTTGATGATGAGCTGGTTCGATGATCCGCATCGCGGCACGCGTGACCTTGATTTGCTGGGCTTCGGT
GACCCCAGCCCGGAGCCGATGCTCGCGACGTTTCGGGAGATCTTGGCGCAGGATGCGGGTGATGGTGTGGAATTCGACGC
TGATGCACTTCGCGTCGACCGCATTCGCGAGGAGCTGGAGTATGGCGGACTCAGACTGAGGACGACGGGCTCGATCAGCG
GCGCCCGGATCAGTCTGACGATCGACATCGGCTTTGGCGATGCACTGGAGCCTGGTGCCGAAGAACTGGAATATCCTTCC
ATGCTCGACTTCCCAATACCCCGACTACGGGGCTATGCGCGTGAAACCGTCATTGCCGAGAAGTTTCAGGCGATGGTGGC
GCTGGGGCGTGCCAACACTCGGATGAAAGATTTCTACGACATCTGGATTCTCAGCAGGTCATTCGAGTTTGGTAATGACA
GGTTGATGCGGGCAATTATCGCCACTTTCGAACGGCGTGAGACGCCGATCCCAACGGTACTACCGGATGCTTTGACGGAA
GCATTTGCCAAGGATCAGCAAAAGCAACGGCAATGGCGAGCGTTTGTTGAAGACGTTGCCCATAATCCGGGTGAATTGAT
GGATGTCATCACGGATATCGCCGCATTCCTGATGCCTCATGCCGTTGTAGCCGCGAGCCGGGGCAAATGA

Antitoxin


Download         Length: 206 a.a.        Molecular weight: 22276.74 Da        Isoelectric Point: 9.8952

>AT77471 WP_094182592.1 NZ_CP021804:3757330-3757947 [Sinorhizobium meliloti]
MPEPISQRQIAHALLTARGIARLVELRDAGVTAATMSRMERNGEVLRLARGLYQLSDAPLDANHSLAEAAKRVPKGVVCL
VSALAFHGLTDQLPRQIWLAIGQKDWAPKSDGTPIHIVRFTESLLNDSVETHVVEGVTVKVFGVVKTIADCFRYRNKIGL
SVAIEGLQEALRQRKATPGEIARQAERGGVATVIRPYIEALTANG

Download         Length: 618 bp

>AT77471 NZ_CP021804:3757330-3757947 [Sinorhizobium meliloti]
ATGCCCGAACCTATCTCCCAGCGCCAAATCGCCCACGCCCTACTGACGGCGCGTGGGATCGCGCGTCTTGTAGAGCTGCG
CGACGCTGGCGTAACAGCCGCCACGATGAGCCGCATGGAGCGGAATGGGGAGGTGCTCCGGCTTGCACGGGGCCTTTATC
AGCTCTCCGACGCGCCGCTCGACGCCAATCATAGCCTGGCTGAAGCCGCCAAACGGGTACCCAAGGGCGTTGTCTGCCTT
GTGTCGGCCCTGGCATTCCACGGGCTGACTGACCAGCTTCCGAGACAGATATGGCTGGCCATCGGCCAGAAAGACTGGGC
TCCCAAATCCGACGGTACACCCATTCACATCGTGCGTTTTACCGAAAGTCTGCTCAACGATAGCGTCGAAACTCATGTTG
TCGAGGGCGTGACTGTAAAGGTCTTTGGGGTTGTCAAAACAATCGCGGACTGTTTTCGATATCGCAACAAGATCGGCTTG
TCGGTGGCGATTGAGGGCCTCCAGGAAGCGCTTCGCCAGCGCAAGGCCACGCCCGGCGAAATTGCCAGACAGGCCGAGCG
TGGCGGTGTCGCCACGGTCATCCGGCCGTATATCGAGGCGCTGACTGCCAATGGCTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References