Detailed information of TA system TA077411

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relB-parE/ParE-RHH
• Location: 2925643..2926199
• Replicon: chromosome
• Accession: NZ_CP021789
• Organism: Xanthomonas oryzae pv. oryzae strain PXO61

Toxin (Protein)

• Gene name: parE
• Uniprot ID: -
• Locus tag: CDO11_RS14550
• Protein ID: WP_229001948.1
• Coordinates: 2925643..2925894 (-)
• Length: 84 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: A0A854CIX2
• Locus tag: CDO11_RS14555
• Protein ID: WP_011408759.1
• Coordinates: 2925921..2926199 (-)
• Length: 93 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
CDO11_RS14500 (CDO11_14280)	2921413..2922504	+	1092	WP_041182166.1	ribonuclease D	-
CDO11_RS14505 (CDO11_14285)	2922580..2922917	-	338	Protein_2641	ATP-dependent DNA ligase	-
CDO11_RS25580 (CDO11_14295)	2923199..2923375	-	177	Protein_2642	DUF3606 domain-containing protein	-
CDO11_RS14520 (CDO11_14300)	2923597..2923998	+	402	WP_011259345.1	H-NS family nucleoid-associated regulatory protein	-
CDO11_RS25990	2924429..2924557	-	129	WP_012444694.1	hypothetical protein	-
CDO11_RS25585 (CDO11_14315)	2924526..2924645	-	120	Protein_2645	IS3 family transposase	-
CDO11_RS14540 (CDO11_14320)	2924862..2925116	-	255	WP_223293127.1	hypothetical protein	-
CDO11_RS25995	2925185..2925319	-	135	WP_011051575.1	hypothetical protein	-
CDO11_RS25590 (CDO11_14325)	2925312..2925566	-	255	WP_198912806.1	hypothetical protein	-
CDO11_RS14550 (CDO11_14330)	2925643..2925894	-	252	WP_229001948.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
CDO11_RS14555 (CDO11_14335)	2925921..2926199	-	279	WP_011408759.1	CopG family ribbon-helix-helix protein	Antitoxin
CDO11_RS14560 (CDO11_14340)	2926395..2926739	-	345	WP_199285675.1	hypothetical protein	-
CDO11_RS14570 (CDO11_14350)	2927645..2928829	-	1185	WP_011408760.1	IS256-like element IS1113 family transposase	-
CDO11_RS14580 (CDO11_14355)	2929410..2930375	+	966	WP_109181928.1	IS1595-like element ISXo5 family transposase	-
CDO11_RS14585 (CDO11_14360)	2930525..2931082	+	558	WP_011259349.1	DNA-3-methyladenine glycosylase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (3-81)

Antitoxin

• Ribbon-helix-helix protein, CopG (5-42)

Sequences

Toxin

Protein

• Length: 84 a.a.
• Molecular weight: 9603.92 Da
• Isoelectric Point: 9.9718

>T77411 WP_229001948.1 NZ_CP021789:c2925894-2925643 [Xanthomonas oryzae pv. oryzae]
MLRLREFLRPKNPDAARRAGEAIRRGVQALGAHPRMGRLIEDLSEQYREWLIDFGDSGYVARYRFDGDTVTILAVRHQKE
AGY

Nucleotide

• Length: 252 bp

>T77411 NZ_CP021789:c2925894-2925643 [Xanthomonas oryzae pv. oryzae]
ATGCTACGGCTGCGTGAATTCCTGAGGCCGAAGAATCCCGATGCCGCGAGGCGGGCCGGCGAAGCGATTAGGCGCGGCGT
CCAGGCTCTCGGTGCCCACCCTCGAATGGGGCGGCTCATAGAAGATCTGTCTGAACAGTATCGGGAGTGGCTTATCGATT
TTGGGGATAGCGGCTATGTGGCTCGGTACCGCTTCGATGGGGATACCGTCACGATTTTGGCCGTGCGACACCAGAAGGAA
GCGGGGTACTGA

Antitoxin

Protein

• Length: 93 a.a.
• Molecular weight: 10826.11 Da
• Isoelectric Point: 4.9736

>AT77411 WP_011408759.1 NZ_CP021789:c2926199-2925921 [Xanthomonas oryzae pv. oryzae]
MVTATSIKLDDELKGRVQHLAESRRRTPHWIMREAIEQYVEREEKREALNRDTLKAWDEFQATGLHVTAEEVDKWLASWG
TDDELPPPECHK

Nucleotide

• Length: 279 bp

>AT77411 NZ_CP021789:c2926199-2925921 [Xanthomonas oryzae pv. oryzae]
ATGGTTACGGCAACTTCCATCAAGCTTGATGATGAATTGAAAGGGCGGGTTCAGCACTTGGCAGAGTCGCGCCGGCGTAC
CCCGCATTGGATCATGCGCGAAGCCATTGAGCAGTACGTCGAGCGCGAGGAAAAGCGCGAGGCGCTGAACCGGGACACGC
TCAAGGCATGGGATGAATTTCAGGCGACTGGCCTGCATGTGACCGCTGAGGAAGTGGACAAGTGGCTCGCTAGCTGGGGA
ACTGACGACGAACTGCCTCCGCCAGAATGCCACAAGTAA

Structures

Antitoxin

• AlphaFold DB: A0A854CIX2