Detailed information of TA system TA077410

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): pmenTA/darT(toxin)
• Location: 1095666..1096411
• Replicon: chromosome
• Accession: NZ_CP021789
• Organism: Xanthomonas oryzae pv. oryzae strain PXO61

Toxin (Protein)

• Gene name: pmenT
• Uniprot ID: -
• Locus tag: CDO11_RS05620
• Protein ID: WP_199285672.1
• Coordinates: 1096082..1096411 (-)
• Length: 110 a.a.

Antitoxin (Protein)

• Gene name: pmenA
• Uniprot ID: -
• Locus tag: CDO11_RS05615
• Protein ID: WP_011407754.1
• Coordinates: 1095666..1096085 (-)
• Length: 140 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
CDO11_RS05590	1091954..1092280	-	327	Protein_998	hypothetical protein	-
CDO11_RS05595 (CDO11_05490)	1092582..1093817	+	1236	WP_011257570.1	ISL3-like element ISXoo13 family transposase	-
CDO11_RS05600 (CDO11_05495)	1093855..1094511	-	657	WP_075246166.1	phosphate phosphatase	-
CDO11_RS05605 (CDO11_05500)	1094646..1095614	-	969	WP_011407317.1	IS5-like element ISXo1 family transposase	-
CDO11_RS05615 (CDO11_05505)	1095666..1096085	-	420	WP_011407754.1	macro domain-containing protein	Antitoxin
CDO11_RS05620 (CDO11_05510)	1096082..1096411	-	330	WP_199285672.1	DUF4433 domain-containing protein	Toxin
CDO11_RS05625 (CDO11_05515)	1096514..1097833	+	1320	WP_109182095.1	IS701 family transposase	-
CDO11_RS05630 (CDO11_05520)	1097877..1098212	-	336	WP_011407757.1	DarT ssDNA thymidine ADP-ribosyltransferase family protein	-
CDO11_RS05635 (CDO11_05525)	1098544..1099470	-	927	WP_011257932.1	Grx4 family monothiol glutaredoxin	-
CDO11_RS05640 (CDO11_05530)	1099516..1100307	+	792	WP_011407758.1	polysaccharide deacetylase family protein	-
CDO11_RS05650 (CDO11_05540)	1100609..1101280	-	672	WP_011407759.1	class I SAM-dependent methyltransferase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	IScluster/Tn	-	-	1092582..1097833	5251

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• ssDNA thymidine ADP-ribosyltransferase, DarT (3-108)

Antitoxin

• Macro domain (18-130)

Sequences

Toxin

Protein

• Length: 110 a.a.
• Molecular weight: 13145.86 Da
• Isoelectric Point: 7.1160

>T77410 WP_199285672.1 NZ_CP021789:c1096411-1096082 [Xanthomonas oryzae pv. oryzae]
MHHVAERRWPFLFTDSHAYCQLASFYSDLSDLDKIDWPLLQARDFRRDPDDPAKFERYQAEALIHRHLPLDGLRGIVCHT
DGLKQTIERQLQERNLKLPVHTRTDWYFR

Nucleotide

• Length: 330 bp

>T77410 NZ_CP021789:c1096411-1096082 [Xanthomonas oryzae pv. oryzae]
TTGCATCATGTCGCCGAACGCCGATGGCCGTTTCTGTTTACTGACAGCCACGCCTACTGCCAGTTGGCGAGCTTCTATTC
CGATTTATCTGATCTCGACAAGATCGACTGGCCGTTGCTCCAAGCACGCGATTTCCGGCGCGACCCAGACGACCCAGCCA
AGTTCGAGCGCTATCAGGCCGAGGCCCTGATTCACCGACACTTGCCGCTTGATGGCCTGCGCGGCATTGTGTGTCATACG
GATGGTTTGAAACAGACCATCGAGCGGCAACTCCAAGAGCGAAACCTGAAATTGCCGGTTCATACCCGCACCGATTGGTA
TTTCCGATGA

Antitoxin

Protein

• Length: 140 a.a.
• Molecular weight: 15607.02 Da
• Isoelectric Point: 6.4733

>AT77410 WP_011407754.1 NZ_CP021789:c1096085-1095666 [Xanthomonas oryzae pv. oryzae]
MITFTQGNLLESGAEALVNTVNTVGVMGKGIALMFKERFKENFLRYAAACKDNQVRIGKIFVTEVNELDGPRWIINFPTK
QHWRGDSRIEWITEGLQDLHRFLIENKVKSIAIPPLGAGNGGLDWAEVRPLIEEVLGNL

Nucleotide

• Length: 420 bp

>AT77410 NZ_CP021789:c1096085-1095666 [Xanthomonas oryzae pv. oryzae]
ATGATCACGTTTACACAAGGCAATCTACTGGAGTCTGGCGCAGAGGCGCTGGTCAACACCGTCAACACCGTCGGCGTGAT
GGGCAAGGGCATCGCGCTGATGTTCAAGGAGCGCTTCAAGGAGAACTTCCTCCGATATGCCGCCGCCTGCAAAGACAACC
AAGTGCGCATTGGCAAAATTTTCGTCACCGAAGTCAACGAACTGGACGGGCCACGCTGGATCATCAATTTTCCGACCAAA
CAGCACTGGCGTGGCGATTCCCGCATCGAATGGATCACTGAAGGATTGCAGGACTTGCACCGTTTTCTGATCGAGAACAA
AGTCAAATCCATTGCCATCCCGCCACTGGGCGCGGGCAATGGAGGATTGGACTGGGCCGAGGTGCGCCCACTGATCGAAG
AAGTACTAGGGAACCTCTGA