77409

Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) EcnAB/-
Location 431455..431805 Replicon chromosome
Accession NZ_CP021789
Organism Xanthomonas oryzae pv. oryzae strain PXO61

Toxin (Protein)


Gene name EcnB Uniprot ID G7TLC7
Locus tag CDO11_RS02165 Protein ID WP_011257368.1
Coordinates 431671..431805 (+) Length 45 a.a.

Antitoxin (Protein)


Gene name EcnA Uniprot ID G7TLC8
Locus tag CDO11_RS02160 Protein ID WP_011407410.1
Coordinates 431455..431607 (+) Length 51 a.a.

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CDO11_RS02130 (CDO11_02105) 427735..428418 - 684 WP_011257363.1 dTMP kinase -
CDO11_RS25110 428898..429440 - 543 Protein_386 GTPase -
CDO11_RS02150 (CDO11_02125) 429437..429892 - 456 Protein_387 hypothetical protein -
CDO11_RS25115 429884..430102 - 219 Protein_388 hypothetical protein -
CDO11_RS02155 (CDO11_02130) 430424..431347 + 924 WP_011407409.1 arginase -
CDO11_RS02160 (CDO11_02135) 431455..431607 + 153 WP_011407410.1 entericidin A/B family lipoprotein Antitoxin
CDO11_RS02165 (CDO11_02140) 431671..431805 + 135 WP_011257368.1 entericidin A/B family lipoprotein Toxin
CDO11_RS02170 (CDO11_02145) 432046..432255 + 210 WP_011407411.1 CsbD family protein -
CDO11_RS02175 (CDO11_02150) 432424..433713 + 1290 WP_069959696.1 tryptophan--tRNA ligase -
CDO11_RS02180 (CDO11_02155) 433844..434788 + 945 WP_027704118.1 MBL fold metallo-hydrolase -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin

(23-42)

Antitoxin

(23-42)


Sequences


Toxin        


Download         Length: 45 a.a.        Molecular weight: 4457.33 Da        Isoelectric Point: 10.2040

>T77409 WP_011257368.1 NZ_CP021789:431671-431805 [Xanthomonas oryzae pv. oryzae]
MKRAIVLLVLSMLSVGLLSGCNTVAGAGKDVKGAGEKVEDAARK

Download         Length: 135 bp

>T77409 NZ_CP021789:431671-431805 [Xanthomonas oryzae pv. oryzae]
ATGAAGCGTGCAATTGTGCTGCTCGTGCTGTCCATGTTGTCGGTCGGTCTGCTGTCGGGCTGCAACACCGTCGCAGGTGC
CGGCAAGGACGTGAAGGGCGCCGGCGAGAAGGTGGAAGACGCAGCGCGTAAGTAA

Antitoxin


Download         Length: 51 a.a.        Molecular weight: 5046.99 Da        Isoelectric Point: 8.7942

>AT77409 WP_011407410.1 NZ_CP021789:431455-431607 [Xanthomonas oryzae pv. oryzae]
MKRLLTLMVLGLFSAGVMTGCNTVAGAGKDLQGAGGKVEKTAEKCSDGKC

Download         Length: 153 bp

>AT77409 NZ_CP021789:431455-431607 [Xanthomonas oryzae pv. oryzae]
ATGAAGCGACTGCTGACACTGATGGTGCTGGGCCTGTTTTCGGCCGGCGTGATGACGGGCTGCAACACCGTGGCTGGCGC
TGGCAAGGACTTGCAGGGCGCGGGTGGGAAGGTCGAGAAAACGGCCGAAAAATGCAGCGATGGTAAGTGCTGA

Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure
AlphaFold DB A0A0C5UG40


Antitoxin

Source ID Structure
AlphaFold DB A0A0C5V759

References