Detailed information of TA system TA077406

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relB-parE/ParE-RHH
• Location: 1588235..1588791
• Replicon: chromosome
• Accession: NZ_CP021788
• Organism: Xanthomonas oryzae pv. oryzae strain PXO61

Toxin (Protein)

• Gene name: parE
• Uniprot ID: -
• Locus tag: CDO19_RS08030
• Protein ID: WP_027703932.1
• Coordinates: 1588501..1588791 (+)
• Length: 97 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: A0A854CIX2
• Locus tag: CDO19_RS08025
• Protein ID: WP_011408759.1
• Coordinates: 1588235..1588513 (+)
• Length: 93 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
CDO19_RS07995	1583352..1583972	-	621	Protein_1435	DNA-3-methyladenine glycosylase	-
CDO19_RS08000	1584059..1585024	-	966	WP_109181928.1	IS1595-like element ISXo5 family transposase	-
CDO19_RS08010	1585605..1586789	+	1185	WP_011408760.1	IS256 family transposase	-
CDO19_RS08015	1587550..1587750	+	201	WP_027703931.1	ribbon-helix-helix protein, CopG family	-
CDO19_RS08020	1587722..1588154	+	433	Protein_1439	relaxase	-
CDO19_RS08025	1588235..1588513	+	279	WP_011408759.1	CopG family ribbon-helix-helix protein	Antitoxin
CDO19_RS08030	1588501..1588791	+	291	WP_027703932.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
CDO19_RS24905	1589052..1589249	+	198	WP_004541336.1	hypothetical protein	-
CDO19_RS08040	1589393..1589572	+	180	WP_015463309.1	hypothetical protein	-
CDO19_RS08050	1589907..1590111	+	205	Protein_1444	kfra protein	-
CDO19_RS08060	1590436..1590837	-	402	WP_011259345.1	H-NS histone family protein	-
CDO19_RS08065	1591058..1591234	+	177	Protein_1446	DUF3606 domain-containing protein	-
CDO19_RS24910	1591250..1591456	+	207	Protein_1447	hypothetical protein	-
CDO19_RS08075	1591516..1591853	+	338	Protein_1448	ATP-dependent DNA ligase	-
CDO19_RS08080	1591929..1593020	-	1092	WP_041182166.1	ribonuclease D	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (4-94)

Antitoxin

• Ribbon-helix-helix protein, CopG (5-42)

Sequences

Toxin

Protein

• Length: 97 a.a.
• Molecular weight: 10915.48 Da
• Isoelectric Point: 9.5554

>T77406 WP_027703932.1 NZ_CP021788:1588501-1588791 [Xanthomonas oryzae pv. oryzae]
MPQVIFAPAAIGDMLRLREFLRPKNPDAARRAGEAIRRGVQALGAHPRMGRLIEDLSEQYREWLIDFGDSGYVARYRFDG
DTVTILAVRHQKEAGY

Nucleotide

• Length: 291 bp

>T77406 NZ_CP021788:1588501-1588791 [Xanthomonas oryzae pv. oryzae]
ATGCCACAAGTAATCTTTGCGCCGGCGGCGATCGGGGACATGCTACGGCTGCGTGAATTCCTGAGGCCGAAGAATCCCGA
TGCCGCGAGGCGGGCCGGCGAAGCGATTAGGCGCGGCGTCCAGGCTCTCGGTGCCCACCCTCGAATGGGGCGGCTCATAG
AAGATCTGTCTGAACAGTATCGGGAGTGGCTTATCGATTTTGGGGATAGCGGCTATGTGGCTCGGTACCGCTTCGATGGG
GATACCGTCACGATTTTGGCCGTGCGACACCAGAAGGAAGCGGGGTACTGA

Antitoxin

Protein

• Length: 93 a.a.
• Molecular weight: 10826.11 Da
• Isoelectric Point: 4.9736

>AT77406 WP_011408759.1 NZ_CP021788:1588235-1588513 [Xanthomonas oryzae pv. oryzae]
MVTATSIKLDDELKGRVQHLAESRRRTPHWIMREAIEQYVEREEKREALNRDTLKAWDEFQATGLHVTAEEVDKWLASWG
TDDELPPPECHK

Nucleotide

• Length: 279 bp

>AT77406 NZ_CP021788:1588235-1588513 [Xanthomonas oryzae pv. oryzae]
ATGGTTACGGCAACTTCCATCAAGCTTGATGATGAATTGAAAGGGCGGGTTCAGCACTTGGCAGAGTCGCGCCGGCGTAC
CCCGCATTGGATCATGCGCGAAGCCATTGAGCAGTACGTCGAGCGCGAGGAAAAGCGCGAGGCGCTGAACCGGGACACGC
TCAAGGCATGGGATGAATTTCAGGCGACTGGCCTGCATGTGACCGCTGAGGAAGTGGACAAGTGGCTCGCTAGCTGGGGA
ACTGACGACGAACTGCCTCCGCCAGAATGCCACAAGTAA

Structures

Antitoxin

• AlphaFold DB: A0A854CIX2