Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1132048..1132193 Replicon chromosome
Accession NZ_CP021757
Organism Klebsiella pneumoniae strain AR_0138

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1132055..1132157 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1132048..1132193 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
AM385_RS05845 1127579..1129012 + 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
AM385_RS05850 1129128..1129367 + 240 WP_002911393.1 YebV family protein -
AM385_RS05855 1129465..1129656 + 192 WP_002911395.1 YebW family protein -
AM385_RS05860 1129653..1130306 - 654 WP_024622748.1 protein-serine/threonine phosphatase -
AM385_RS05865 1130463..1131431 + 969 WP_014907334.1 VirK/YbjX family protein -
AM385_RS28890 1131536..1131679 + 144 WP_038431282.1 Ecr family regulatory small membrane protein -
- 1132048..1132193 + 146 - - Antitoxin
- 1132055..1132157 - 103 - - Toxin
AM385_RS05875 1132316..1132654 - 339 WP_002911404.1 YebY family protein -
AM385_RS05880 1132671..1133540 - 870 WP_004175431.1 copper homeostasis membrane protein CopD -
AM385_RS05885 1133544..1133918 - 375 WP_039819395.1 CopC domain-containing protein YobA -
AM385_RS05890 1134031..1134261 + 231 WP_002911406.1 DNA polymerase III subunit theta -
AM385_RS05895 1134340..1134999 + 660 WP_002911407.1 exodeoxyribonuclease X -
AM385_RS05900 1135003..1137063 - 2061 WP_004151449.1 oligopeptidase B -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T77322 NZ_CP021757:c1132157-1132055 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT77322 NZ_CP021757:1132048-1132193 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References