Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 3324529..3324674 Replicon chromosome
Accession NZ_CP021751
Organism Klebsiella pneumoniae strain AR_0113

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 3324536..3324638 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 3324529..3324674 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
AM360_RS16875 3320061..3321494 + 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
AM360_RS16880 3321610..3321849 + 240 WP_002911393.1 YebV family protein -
AM360_RS16885 3321947..3322138 + 192 WP_002911395.1 YebW family protein -
AM360_RS16890 3322135..3322788 - 654 WP_002911396.1 protein-serine/threonine phosphatase -
AM360_RS16895 3322945..3323913 + 969 WP_004151446.1 VirK/YbjX family protein -
AM360_RS30195 3324018..3324161 + 144 WP_002911398.1 Ecr family regulatory small membrane protein -
- 3324529..3324674 + 146 - - Antitoxin
- 3324536..3324638 - 103 - - Toxin
AM360_RS16905 3324797..3325135 - 339 WP_002911404.1 YebY family protein -
AM360_RS16910 3325152..3326021 - 870 WP_004151447.1 copper homeostasis membrane protein CopD -
AM360_RS16915 3326025..3326399 - 375 WP_004151448.1 CopC domain-containing protein YobA -
AM360_RS16920 3326512..3326742 + 231 WP_002911406.1 DNA polymerase III subunit theta -
AM360_RS16925 3326821..3327480 + 660 WP_002911407.1 exodeoxyribonuclease X -
AM360_RS16930 3327484..3329544 - 2061 WP_004151449.1 oligopeptidase B -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T77303 NZ_CP021751:c3324638-3324536 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT77303 NZ_CP021751:3324529-3324674 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References